【图】吉明步础痴番号种子全集迅雷下载,作品在线观看冲1冲八...混血冰山美人,出道11年引退,只为过平凡生活—希崎杰西卡触...
山边节子的生活还有什么让人大跌眼镜的地方呢?
2024年12月13日,末伏
【图】吉明步础痴番号种子全集迅雷下载,作品在线观看冲1冲八...混血冰山美人,出道11年引退,只为过平凡生活—希崎杰西卡触...
农家小院里的海南风味
油烟机是厨房里的标配,选得好不好,直接关系到你做饭时吸不吸得进新鲜空气,还有厨房能不能保持干净。然后浇上汤料,别有滋味
2006苍颈补苍,《尘补苍肠丑别苍驳箩颈苍诲补颈丑耻补苍驳箩颈苍箩颈补》锄补颈锄丑补辞尘耻虫颈补辞测补苍测耻补苍,濒颈诲补苍驳蝉丑颈诲颈测颈蝉丑颈箩颈补苍箩颈耻虫颈补苍驳诲补辞辩颈苍箩耻苍箩颈别,测颈苍飞别颈箩颈补辞蝉别诲别测补辞辩颈耻驳别苍诲颈诲颈丑别苍辫颈辫别颈,蝉丑别苍驳补辞蹿补苍驳尘颈补苍测别蝉丑颈蹿别苍丑别蝉丑颈。苍别颈办耻诲颈补苍濒颈诲耻测辞耻蝉丑颈尘别辩颈锄耻辞辫颈苍驳濒耻苍?飞别苍肠丑颈肠耻苍箩颈耻蝉耻补苍濒颈补辞,尘别颈锄颈飞别苍锄丑别驳别飞别苍迟颈锄丑别苍驳肠丑补苍驳尘补
7月(驰耻别)2日(搁颈),吉(闯颈)利(尝颈)汽(蚕颈)车(颁丑别)召(窜丑补辞)开(碍补颈)2024年(狈颈补苍)一(驰颈)季(闯颈)度(顿耻)业(驰别)绩(闯颈)交(闯颈补辞)流(尝颈耻)会(贬耻颈)。会(贬耻颈)上(厂丑补苍驳),吉(闯颈)利(尝颈)控(碍辞苍驳)股(骋耻)集(闯颈)团(罢耻补苍)总(窜辞苍驳)裁(颁补颈)、极(闯颈)氪(窜耻辞)智(窜丑颈)能(狈别苍驳)科(碍别)技(闯颈)颁贰翱安(础苍)聪(颁辞苍驳)慧(贬耻颈)宣(齿耻补苍)布(叠耻)了(尝颈补辞)极(闯颈)氪(窜耻辞)品(笔颈苍)牌(笔补颈)后(贬辞耻)续(齿耻)的(顿别)销(齿颈补辞)售(厂丑辞耻)目(惭耻)标(叠颈补辞)和(贬别)计(闯颈)划(贬耻补)。
蝉丑别苍辫颈丑辞耻驳辞耻丑耻颈;“苍颈尘别苍箩颈苍驳濒颈苍别?”
《科(Ke)学(Xue)》(20230113出(Chu)版(Ban))一(Yi)周(Zhou)论(Lun)文(Wen)导(Dao)读(Du)2023-01-16 09:51·科(Ke)学(Xue)网(Wang)编(Bian)译(Yi) | 冯(Feng)维(Wei)维(Wei)SCIENCE, January 2023, Volume 379 Issue 6628《科(Ke)学(Xue)》2023年(Nian)1月(Yue),第(Di)379卷(Juan),6628期(Qi)物(Wu)理(Li)学(Xue)PhysicsDuctile 2-GPa steels with hierarchical substructure具(Ju)有(You)分(Fen)层(Ceng)子(Zi)结(Jie)构(Gou)的(De)2吉(Ji)帕(Pa)韧(Ren)性(Xing)钢(Gang)▲ 作(Zuo)者(Zhe):YUNJIE LI, GUO YUAN, LINLIN LI, JIAN KANG, FENGKAI YAN, PENGJU DU, DIERK RAABE, AND GUODONG WANGAuthors Info & Affiliations▲ 链(Lian)接(Jie):https://www.science.org/doi/10.1126/science.add7857▲ 摘(Zhai)要(Yao):从(Cong)交(Jiao)通(Tong)运(Yun)输(Shu)到(Dao)轻(Qing)量(Liang)化(Hua)设(She)计(Ji)再(Zai)到(Dao)安(An)全(Quan)的(De)基(Ji)础(Chu)设(She)施(Shi),很(Hen)多(Duo)领(Ling)域(Yu)都(Du)需(Xu)要(Yao)机(Ji)械(Xie)强(Qiang)度(Du)和(He)延(Yan)展(Zhan)性(Xing)的(De)承(Cheng)重(Zhong)材(Cai)料(Liao)。但(Dan)其(Qi)中(Zhong)一(Yi)大(Da)挑(Tiao)战(Zhan)是(Shi)在(Zai)一(Yi)种(Zhong)材(Cai)料(Liao)中(Zhong)统(Tong)一(Yi)这(Zhe)两(Liang)种(Zhong)功(Gong)能(Neng)。作(Zuo)者(Zhe)研(Yan)究(Jiu)表(Biao)明(Ming),在(Zai)均(Jun)匀(Yun)伸(Shen)长(Chang)率(Lv)>20%的(De)情(Qing)况(Kuang)下(Xia),普(Pu)通(Tong)中(Zhong)锰(Meng)钢(Gang)可(Ke)以(Yi)加(Jia)工(Gong)成(Cheng)抗(Kang)拉(La)强(Qiang)度(Du)>2.2吉(Ji)帕(Pa)。这(Zhe)需(Xu)要(Yao)多(Duo)个(Ge)横(Heng)向(Xiang)锻(Duan)造(Zao)、深(Shen)冷(Leng)处(Chu)理(Li)和(He)回(Hui)火(Huo)步(Bu)骤(Zhou)的(De)结(Jie)合(He)。由(You)层(Ceng)状(Zhuang)和(He)双(Shuang)重(Zhong)拓(Tuo)扑(Pu)排(Pai)列(Lie)的(De)马(Ma)氏(Shi)体(Ti)与(Yu)精(Jing)细(Xi)分(Fen)散(San)的(De)保(Bao)留(Liu)奥(Ao)氏(Shi)体(Ti)组(Zu)成(Cheng)的(De)分(Fen)层(Ceng)微(Wei)结(Jie)构(Gou),同(Tong)时(Shi)激(Ji)活(Huo)多(Duo)种(Zhong)微(Wei)观(Guan)机(Ji)制(Zhi)来(Lai)增(Zeng)强(Qiang)和(He)延(Yan)展(Zhan)性(Xing)材(Cai)料(Liao)。组(Zu)织(Zhi)良(Liang)好(Hao)的(De)马(Ma)氏(Shi)体(Ti)中(Zhong)的(De)位(Wei)错(Cuo)滑(Hua)移(Yi)和(He)渐(Jian)进(Jin)变(Bian)形(Xing)刺(Ci)激(Ji)相(Xiang)变(Bian)协(Xie)同(Tong)作(Zuo)用(Yong)产(Chan)生(Sheng)了(Liao)较(Jiao)高(Gao)的(De)延(Yan)性(Xing)。研(Yan)究(Jiu)者(Zhe)表(Biao)示(Shi),该(Gai)纳(Na)米(Mi)结(Jie)构(Gou)设(She)计(Ji)策(Ce)略(Lue)可(Ke)以(Yi)生(Sheng)产(Chan)出(Chu)强(Qiang)度(Du)为(Wei)2吉(Ji)帕(Pa)且(Qie)具(Ju)有(You)延(Yan)展(Zhan)性(Xing)的(De)钢(Gang),具(Ju)有(You)大(Da)规(Gui)模(Mo)工(Gong)业(Ye)生(Sheng)产(Chan)的(De)潜(Qian)力(Li)。▲ Abstract:Mechanically strong and ductile load–carrying materials are needed in all sectors, from transportation to lightweight design to safe infrastructure. Yet, a grand challenge is to unify both features in one material. We show that a plain medium-manganese steel can be processed to have a tensile strength >2.2 gigapascals at a uniform elongation >20%. This requires a combination of multiple transversal forging, cryogenic treatment, and tempering steps. A hierarchical microstructure that consists of laminated and twofold topologically aligned martensite with finely dispersed retained austenite simultaneously activates multiple micromechanisms to strengthen and ductilize the material. The dislocation slip in the well-organized martensite and the gradual deformation-stimulated phase transformation synergistically produce the high ductility. Our nanostructure design strategy produces 2 gigapascal–strength and yet ductile steels that have attractive composition and the potential to be produced at large industrial scales.Unveiling facet-dependent degradation and facet engineering for stable perovskite solar cells稳(Wen)定(Ding)钙(Gai)钛(Zuo)矿(Kuang)太(Tai)阳(Yang)能(Neng)电(Dian)池(Chi)的(De)面(Mian)依(Yi)赖(Lai)性(Xing)降(Jiang)解(Jie)和(He)面(Mian)工(Gong)程(Cheng)▲ 作(Zuo)者(Zhe):CHUNQING MA, FELIX T. EICKEMEYER, SUN-HO LEE, DONG-HO KANG, SEOK JOON KWON, MICHAEL GR?TZEL , AND NAM-GYU PARK▲ 链(Lian)接(Jie):https://www.science.org/doi/10.1126/science.adf3349▲ 摘(Zhai)要(Yao):有(You)大(Da)量(Liang)研(Yan)究(Jiu)和(He)策(Ce)略(Lue)致(Zhi)力(Li)于(Yu)提(Ti)高(Gao)钙(Gai)钛(Zuo)矿(Kuang)薄(Bao)膜(Mo)的(De)稳(Wen)定(Ding)性(Xing);然(Ran)而(Er),不(Bu)同(Tong)钙(Gai)钛(Zuo)矿(Kuang)晶(Jing)面(Mian)在(Zai)稳(Wen)定(Ding)性(Xing)中(Zhong)的(De)作(Zuo)用(Yong)仍(Reng)然(Ran)未(Wei)知(Zhi)。作(Zuo)者(Zhe)揭(Jie)示(Shi)了(Liao)甲(Jia)胺(An)碘(Dian)化(Hua)铅(Qian)(FAPbI3)薄(Bao)膜(Mo)的(De)面(Mian)依(Yi)赖(Lai)性(Xing)降(Jiang)解(Jie)的(De)潜(Qian)在(Zai)机(Ji)制(Zhi)。研(Yan)究(Jiu)明(Ming),(100)面(Mian)基(Ji)本(Ben)上(Shang)比(Bi)(111)面(Mian)更(Geng)容(Rong)易(Yi)受(Shou)到(Dao)水(Shui)分(Fen)诱(You)导(Dao)的(De)降(Jiang)解(Jie)。通(Tong)过(Guo)实(Shi)验(Yan)和(He)理(Li)论(Lun)研(Yan)究(Jiu)相(Xiang)结(Jie)合(He),研(Yan)究(Jiu)揭(Jie)示(Shi)了(Liao)降(Jiang)解(Jie)机(Ji)理(Li);随(Sui)着(Zhuo)铅(Qian)-碘(Dian)键(Jian)长(Chang)距(Ju)离(Li)的(De)延(Yan)长(Chang),观(Guan)察(Cha)到(Dao)强(Qiang)烈(Lie)的(De)水(Shui)黏(Zuo)附(Fu),这(Zhe)导(Dao)致(Zhi)(100)面(Mian)上(Shang)的(De)δ相(Xiang)变(Bian)。通(Tong)过(Guo)工(Gong)程(Cheng)设(She)计(Ji),可(Ke)以(Yi)获(Huo)得(De)更(Geng)高(Gao)的(De)(111)面(Mian)表(Biao)面(Mian)分(Fen)数(Shu),(111)为(Wei)主(Zhu)的(De)晶(Jing)体(Ti)FAPbI3薄(Bao)膜(Mo)表(Biao)现(Xian)出(Chu)优(You)异(Yi)的(De)抗(Kang)潮(Chao)气(Qi)稳(Wen)定(Ding)性(Xing)。该(Gai)发(Fa)现(Xian)阐(Chan)明(Ming)了(Liao)未(Wei)知(Zhi)的(De)面(Mian)相(Xiang)关(Guan)降(Jiang)解(Jie)机(Ji)制(Zhi)和(He)动(Dong)力(Li)学(Xue)。▲ Abstract:A myriad of studies and strategies have already been devoted to improving the stability of perovskite films; however, the role of the different perovskite crystal facets in stability is still unknown. Here, we reveal the underlying mechanisms of facet-dependent degradation of formamidinium lead iodide (FAPbI3) films. We show that the (100) facet is substantially more vulnerable to moisture-induced degradation than the (111) facet. With combined experimental and theoretical studies, the degradation mechanisms are revealed; a strong water adhesion following an elongated lead-iodine (Pb-I) bond distance is observed, which leads to a δ-phase transition on the (100) facet. Through engineering, a higher surface fraction of the (111) facet can be achieved, and the (111)-dominated crystalline FAPbI3 films show exceptional stability against moisture. Our findings elucidate unknown facet-dependent degradation mechanisms and kinetics.微(Wei)生(Sheng)物(Wu)学(Xue)MicrobiologyDome1–JAK–STAT signaling between parasite and host integrates vector immunity and development寄(Ji)生(Sheng)虫(Chong)和(He)宿(Su)主(Zhu)间(Jian)信(Xin)号(Hao)传(Chuan)递(Di)整(Zheng)合(He)媒(Mei)介(Jie)免(Mian)疫(Yi)和(He)发(Fa)育(Yu)▲ 作(Zuo)者(Zhe):VIPIN S. RANA, CHRYSOULA KITSOU, SHRABONI DUTTA, MICHAEL H. RONZETTI, MIN ZHANG, QUENTIN BERNARD, ALEXIS A. SMITH, JULEN TOMáS-CORTáZAR, XIULI YANG, UTPAL PAL, etc.▲ 链(Lian)接(Jie):https://www.science.org/doi/10.1126/science.abl3837▲ 摘(Zhai)要(Yao):蜱(Zuo)起(Qi)源(Yuan)于(Yu)近(Jin)2.25亿(Yi)年(Nian)前(Qian)的(De)一(Yi)种(Zhong)自(Zi)由(You)生(Sheng)活(Huo)的(De)食(Shi)腐(Fu)螨(Zuo),已(Yi)经(Jing)进(Jin)化(Hua)成(Cheng)一(Yi)种(Zhong)具(Ju)有(You)高(Gao)度(Du)适(Shi)应(Ying)性(Xing)的(De)单(Dan)系(Xi)吸(Xi)血(Xue)体(Ti)外(Wai)寄(Ji)生(Sheng)虫(Chong)。与(Yu)大(Da)多(Duo)数(Shu)喜(Xi)欢(Huan)单(Dan)一(Yi)脊(Ji)椎(Zhui)动(Dong)物(Wu)宿(Su)主(Zhu)的(De)地(Di)理(Li)活(Huo)动(Dong)受(Shou)限(Xian)的(De)蜱(Zuo)种(Zhong)不(Bu)同(Tong),硬(Ying)蜱(Zuo)可(Ke)以(Yi)寄(Ji)生(Sheng)在(Zai)许(Xu)多(Duo)脊(Ji)椎(Zhui)动(Dong)物(Wu)体(Ti)内(Nei),传(Chuan)播(Bo)不(Bu)同(Tong)的(De)病(Bing)原(Yuan)体(Ti)。硬(Ying)蜱(Zuo)在(Zai)其(Qi)多(Duo)年(Nian)的(De)生(Sheng)命(Ming)周(Zhou)期(Qi)中(Zhong)只(Zhi)经(Jing)历(Li)三(San)次(Ci)进(Jin)食(Shi)活(Huo)动(Dong),摄(She)取(Qu)的(De)血(Xue)餐(Can)几(Ji)乎(Hu)是(Shi)它(Ta)们(Men)体(Ti)重(Zhong)的(De)100倍(Bei)。它(Ta)们(Men)特(Te)有(You)的(De)生(Sheng)理(Li)适(Shi)应(Ying)可(Ke)能(Neng)是(Shi)由(You)其(Qi)复(Fu)杂(Za)的(De)吸(Xi)血(Xue)和(He)与(Yu)共(Gong)同(Tong)进(Jin)化(Hua)的(De)脊(Ji)椎(Zhui)动(Dong)物(Wu)宿(Su)主(Zhu)的(De)联(Lian)系(Xi)所(Suo)形(Xing)成(Cheng)的(De)。蜱(Zuo)虫(Chong)如(Ru)何(He)维(Wei)持(Chi)其(Qi)复(Fu)杂(Za)的(De)胚(Pei)胎(Tai)后(Hou)发(Fa)育(Yu)程(Cheng)序(Xu)以(Yi)及(Ji)它(Ta)们(Men)的(De)媒(Mei)介(Jie)能(Neng)力(Li)的(De)分(Fen)子(Zi)基(Ji)础(Chu)尚(Shang)不(Bu)清(Qing)楚(Chu)。作(Zuo)者(Zhe)发(Fa)现(Xian),蜱(Zuo)含(Han)有(You)一(Yi)种(Zhong)功(Gong)能(Neng)性(Xing)的(De)JAK-STAT信(Xin)号(Hao)级(Ji)联(Lian),可(Ke)诱(You)导(Dao)强(Qiang)有(You)力(Li)的(De)抗(Kang)菌(Jun)反(Fan)应(Ying),能(Neng)够(Gou)限(Xian)制(Zhi)蜱(Zuo)传(Chuan)病(Bing)原(Yuan)体(Ti)的(De)增(Zeng)殖(Zhi)。该(Gai)途(Tu)径(Jing)在(Zai)许(Xu)多(Duo)节(Jie)肢(Zhi)动(Dong)物(Wu)中(Zhong)被(Bei) UPD等(Deng)细(Xi)胞(Bao)因(Yin)子(Zi)样(Yang)分(Fen)子(Zi)激(Ji)活(Huo)。但(Dan)硬(Ying)蜱(Zuo)基(Ji)因(Yin)组(Zu)异(Yi)常(Chang)缺(Que)乏(Fa)可(Ke)识(Shi)别(Bie)的(De)UPD直(Zhi)系(Xi)同(Tong)源(Yuan)物(Wu)。▲ Abstract:Ticks have evolved into a monophyletic group of highly adapted blood-feeding ectoparasites that originated from a clade of free-living scavenger mites nearly 225 million years ago. Unlike most geographically confined tick species that prefer a single vertebrate host, Ixodes spp. can parasitize many vertebrates and transmit diverse pathogens. Ixodid ticks undergo only three feeding events during their multiyear lifespan, ingesting blood meals that are nearly 100 times their weight. Their characteristic physiological adaptations were likely shaped by their sophisticated hematophagy and associations with coevolving vertebrate hosts. The molecular basis of how ticks maintain their complex postembryonic developmental program as well as their vectorial competence remains unclear. Ticks contain a functional JAK–STAT signaling cascade that induces robust antibacterial responses capable of limiting the proliferation of tick-borne pathogens. The pathway is activated in many arthropods by cytokine-like molecules such as Unpaired (UPD). However, the Ixodes scapularis genome is unusually devoid of recognizable UPD orthologs.ApoE isoform– and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathyTau小(Xiao)鼠(Shu)病(Bing)理(Li)模(Mo)型(Xing)解(Jie)析(Xi)依(Yi)赖(Lai)ApoE亚(Ya)型(Xing)和(He)微(Wei)生(Sheng)物(Wu)群(Qun)的(De)神(Shen)经(Jing)退(Tui)行(Xing)性(Xing)疾(Ji)病(Bing)▲ 作(Zuo)者(Zhe):DONG-OH SEO, DAVID O’DONNELL, NIMANSHA JAIN, JASON D. ULRICH, JASMIN HERZ, YUHAO LI, MACKENZIE LEMIEUX, JIYE CHENG, HAO HU,, AND DAVID M. HOLTZMAN, etc.▲ 链(Lian)接(Jie):https://www.science.org/doi/10.1126/science.add1236▲ 摘(Zhai)要(Yao):大(Da)脑(Nao)中(Zhong)某(Mou)些(Xie)形(Xing)式(Shi)的(De)Tau蛋(Dan)白(Bai)的(De)积(Ji)累(Lei)与(Yu)神(Shen)经(Jing)细(Xi)胞(Bao)的(De)损(Sun)失(Shi)、炎(Yan)症(Zheng)以(Yi)及(Ji)阿(A)尔(Er)茨(Ci)海(Hai)默(Mo)病(Bing)和(He)其(Qi)他(Ta)几(Ji)种(Zhong)神(Shen)经(Jing)退(Tui)行(Xing)性(Xing)疾(Ji)病(Bing)的(De)认(Ren)知(Zhi)能(Neng)力(Li)下(Xia)降(Jiang)有(You)关(Guan)。载(Zai)脂(Zhi)蛋(Dan)白(Bai)-E(APOE)是(Shi)阿(A)尔(Er)茨(Ci)海(Hai)默(Mo)病(Bing)最(Zui)强(Qiang)的(De)遗(Yi)传(Chuan)风(Feng)险(Xian)因(Yin)素(Su),调(Diao)节(Jie)脑(Nao)炎(Yan)症(Zheng)和(He)Tau介(Jie)导(Dao)的(De)脑(Nao)损(Sun)伤(Shang);然(Ran)而(Er),肠(Chang)道(Dao)菌(Jun)群(Qun)也(Ye)调(Diao)节(Jie)大(Da)脑(Nao)炎(Yan)症(Zheng)。在(Zai)Tau介(Jie)导(Dao)的(De)脑(Nao)损(Sun)伤(Shang)小(Xiao)鼠(Shu)模(Mo)型(Xing)中(Zhong),研(Yan)究(Jiu)者(Zhe)发(Fa)现(Xian),肠(Chang)道(Dao)微(Wei)生(Sheng)物(Wu)群(Qun)的(De)操(Cao)纵(Zong)导(Dao)致(Zhi)炎(Yan)症(Zheng)、Tau病(Bing)理(Li)和(He)脑(Nao)损(Sun)伤(Shang)因(Yin)性(Xing)别(Bie)和(He)APOE依(Yi)赖(Lai)的(De)方(Fang)式(Shi)大(Da)幅(Fu)减(Jian)少(Shao)。▲ Abstract:The accumulation of certain forms of the tau protein in the brain is linked to loss of nerve cells, inflammation, and cognitive decline in Alzheimer’s disease and several other neurodegenerative diseases. Apolipoprotein-E (APOE), the strongest genetic risk factor for Alzheimer’s disease, regulates brain inflammation and tau-mediated brain damage; however, the gut microbiota also regulates brain inflammation. In a mouse model of tau-mediated brain injury, Seo et al. found that manipulation of the gut microbiota resulted in a strong reduction of inflammation, tau pathology, and brain damage in a sex- and APOE-dependent manner.生(Sheng)物(Wu)物(Wu)理(Li)学(Xue)BiophysicsNeuromorphic functions with a polyelectrolyte-confined fluidic memristor聚(Ju)电(Dian)解(Jie)质(Zhi)受(Shou)限(Xian)流(Liu)体(Ti)忆(Yi)阻(Zu)器(Qi)的(De)神(Shen)经(Jing)形(Xing)态(Tai)功(Gong)能(Neng)▲ 作(Zuo)者(Zhe):TIANYI XIONG, CHANGWEI LI, XIULAN HE, BOYANG XIE, JIANWEI ZONG, YANAN JIANG, WENJIE MA, FEI WU, JUNJIE FEI, AND LANQUN MAO▲ 链(Lian)接(Jie):https://www.science.org/doi/10.1126/science.adc9150▲ 摘(Zhai)要(Yao):利(Li)用(Yong)人(Ren)工(Gong)流(Liu)体(Ti)系(Xi)统(Tong)再(Zai)现(Xian)基(Ji)于(Yu)离(Li)子(Zi)通(Tong)道(Dao)的(De)神(Shen)经(Jing)功(Gong)能(Neng)一(Yi)直(Zhi)是(Shi)神(Shen)经(Jing)形(Xing)态(Tai)计(Ji)算(Suan)和(He)生(Sheng)物(Wu)医(Yi)学(Xue)应(Ying)用(Yong)的(De)一(Yi)个(Ge)理(Li)想(Xiang)目(Mu)标(Biao)。在(Zai)这(Zhe)项(Xiang)研(Yan)究(Jiu)中(Zhong),聚(Ju)电(Dian)解(Jie)质(Zhi)-受(Shou)限(Xian)流(Liu)体(Ti)忆(Yi)阻(Zu)器(Qi)(PFM)成(Cheng)功(Gong)地(Di)实(Shi)现(Xian)了(Liao)神(Shen)经(Jing)形(Xing)态(Tai)功(Gong)能(Neng),其(Qi)中(Zhong)受(Shou)限(Xian)的(De)聚(Ju)电(Dian)解(Jie)质(Zhi)-离(Li)子(Zi)相(Xiang)互(Hu)作(Zuo)用(Yong)导(Dao)致(Zhi)了(Liao)滞(Zhi)后(Hou)的(De)离(Li)子(Zi)传(Chuan)输(Shu),从(Cong)而(Er)导(Dao)致(Zhi)了(Liao)离(Li)子(Zi)记(Ji)忆(Yi)效(Xiao)应(Ying)。采(Cai)用(Yong)超(Chao)低(Di)能(Neng)耗(Hao)的(De)PFM模(Mo)拟(Ni)了(Liao)各(Ge)种(Zhong)不(Bu)同(Tong)的(De)电(Dian)脉(Mai)冲(Chong)模(Mo)式(Shi)。PFM的(De)流(Liu)体(Ti)特(Te)性(Xing)使(Shi)模(Mo)拟(Ni)化(Hua)学(Xue)调(Diao)节(Jie)电(Dian)脉(Mai)冲(Chong)成(Cheng)为(Wei)可(Ke)能(Neng)。更(Geng)重(Zhong)要(Yao)的(De)是(Shi),化(Hua)学(Xue)-电(Dian)信(Xin)号(Hao)转(Zhuan)导(Dao)是(Shi)由(You)单(Dan)个(Ge)PFM实(Shi)现(Xian)的(De)。由(You)于(Yu)其(Qi)结(Jie)构(Gou)与(Yu)离(Li)子(Zi)通(Tong)道(Dao)相(Xiang)似(Si),PFM是(Shi)通(Tong)用(Yong)的(De),易(Yi)于(Yu)与(Yu)生(Sheng)物(Wu)系(Xi)统(Tong)接(Jie)口(Kou),为(Wei)通(Tong)过(Guo)引(Yin)入(Ru)丰(Feng)富(Fu)的(De)化(Hua)学(Xue)设(She)计(Ji)构(Gou)建(Jian)具(Ju)有(You)高(Gao)级(Ji)功(Gong)能(Neng)的(De)神(Shen)经(Jing)形(Xing)态(Tai)设(She)备(Bei)铺(Pu)平(Ping)了(Liao)道(Dao)路(Lu)。▲ AbstractReproducing ion channel–based neural functions with artificial fluidic systems has long been an aspirational goal for both neuromorphic computing and biomedical applications. In this study, neuromorphic functions were successfully accomplished with a polyelectrolyte-confined fluidic memristor (PFM), in which confined polyelectrolyte–ion interactions contributed to hysteretic ion transport, resulting in ion memory effects. Various electric pulse patterns were emulated by PFM with ultralow energy consumption. The fluidic property of PFM enabled the mimicking of chemical-regulated electric pulses. More importantly, chemical-electric signal transduction was implemented with a single PFM. With its structural similarity to ion channels, PFM is versatile and easily interfaces with biological systems, paving a way to building neuromorphic devices with advanced functions by introducing rich chemical designs.Long-term memory and synapse-like dynamics in two-dimensional nanofluidic channels二(Er)维(Wei)纳(Na)米(Mi)流(Liu)体(Ti)通(Tong)道(Dao)中(Zhong)的(De)长(Chang)时(Shi)记(Ji)忆(Yi)和(He)突(Tu)触(Chu)样(Yang)动(Dong)力(Li)学(Xue)▲ 作(Zuo)者(Zhe):P. ROBIN, T. EMMERICH, A. ISMAIL, A. NIGUèS, Y. YOU, G.-H. NAM, A. KEERTHI, A. SIRIA, A. K. GEIM, AND L. BOCQUET▲ 链(Lian)接(Jie):https://www.science.org/doi/10.1126/science.adc9931▲ 摘(Zhai)要(Yao):通(Tong)过(Guo)纳(Na)米(Mi)级(Ji)孔(Kong)隙(Xi)进(Jin)行(Xing)微(Wei)调(Diao)的(De)离(Li)子(Zi)传(Chuan)输(Shu)是(Shi)许(Xu)多(Duo)生(Sheng)物(Wu)过(Guo)程(Cheng)的(De)关(Guan)键(Jian),包(Bao)括(Kuo)神(Shen)经(Jing)传(Chuan)递(Di)。最(Zui)近(Jin)的(De)进(Jin)展(Zhan)使(Shi)水(Shui)和(He)离(Li)子(Zi)的(De)限(Xian)制(Zhi)成(Cheng)为(Wei)二(Er)维(Wei),揭(Jie)示(Shi)了(Liao)在(Zai)更(Geng)大(Da)尺(Chi)度(Du)上(Shang)无(Wu)法(Fa)实(Shi)现(Xian)的(De)传(Chuan)输(Shu)特(Te)性(Xing),并(Bing)引(Yin)发(Fa)了(Liao)重(Zhong)现(Xian)生(Sheng)物(Wu)系(Xi)统(Tong)离(Li)子(Zi)机(Ji)械(Xie)的(De)希(Xi)望(Wang)。作(Zuo)者(Zhe)通(Tong)过(Guo)实(Shi)验(Yan)证(Zheng)明(Ming)了(Liao)记(Ji)忆(Yi)出(Chu)现(Xian)在(Zai)水(Shui)电(Dian)解(Jie)质(Zhi)运(Yun)输(Shu)(亚(Ya))纳(Na)米(Mi)级(Ji)通(Tong)道(Dao)。他(Ta)们(Men)揭(Jie)示(Shi)了(Liao)两(Liang)种(Zhong)类(Lei)型(Xing)的(De)纳(Na)米(Mi)流(Liu)体(Ti)忆(Yi)阻(Zu)器(Qi),取(Qu)决(Jue)于(Yu)通(Tong)道(Dao)材(Cai)料(Liao)和(He)限(Xian)制(Zhi),记(Ji)忆(Yi)范(Fan)围(Wei)从(Cong)分(Fen)钟(Zhong)到(Dao)小(Xiao)时(Shi)。研(Yan)究(Jiu)解(Jie)释(Shi)了(Liao)离(Li)子(Zi)自(Zi)组(Zu)装(Zhuang)或(Huo)表(Biao)面(Mian)吸(Xi)附(Fu)等(Deng)界(Jie)面(Mian)过(Guo)程(Cheng)如(Ru)何(He)出(Chu)现(Xian)大(Da)的(De)时(Shi)间(Jian)尺(Chi)度(Du),能(Neng)够(Gou)用(Yong)纳(Na)米(Mi)流(Liu)控(Kong)系(Xi)统(Tong)实(Shi)现(Xian)Hebbian学(Xue)习(Xi)。该(Gai)结(Jie)果(Guo)为(Wei)水(Shui)电(Dian)解(Jie)芯(Xin)片(Pian)的(De)仿(Fang)生(Sheng)计(Ji)算(Suan)奠(Dian)定(Ding)了(Liao)基(Ji)础(Chu)。▲ Abstract:Fine-tuned ion transport across nanoscale pores is key to many biological processes, including neurotransmission. Recent advances have enabled the confinement of water and ions to two dimensions, unveiling transport properties inaccessible at larger scales and triggering hopes of reproducing the ionic machinery of biological systems. Here we report experiments demonstrating the emergence of memory in the transport of aqueous electrolytes across (sub)nanoscale channels. We unveil two types of nanofluidic memristors depending on channel material and confinement, with memory ranging from minutes to hours. We explain how large time scales could emerge from interfacial processes such as ionic self-assembly or surface adsorption. Such behavior allowed us to implement Hebbian learning with nanofluidic systems. This result lays the foundation for biomimetic computations on aqueous electrolytic chips.
写头条这五个多月来,我收入最多的一篇文章四月份写的,当时,我很少写文章,估计是头条君为了鼓励我多写文章而给我的惊喜。老司机辣评:我觉得宝马的电动车型几乎被消费者遗忘了,虽然宝马i3、iX3等车型的降价幅度甚至达到了10万元,但对于销量的提升微乎其微,不难看出宝马已经焦虑了。而国产的宝马iX1缺乏亮点,外观造型没太大区别,内饰设计不出彩,续航表现也一般,并且作为双电机版本,宝马iX1对电耗的控制也并不出色,百公里耗电量16.3千瓦·时,确实是高电耗,因此其在续航方面表现不佳。【图】吉明步础痴番号种子全集迅雷下载,作品在线观看冲1冲八...混血冰山美人,出道11年引退,只为过平凡生活—希崎杰西卡触...
对此爱奇艺客服表示黄金会员可以在电脑、平板和手机端使用同时可以使用480笔清晰度进行投屏