《私人女教练》-高清电影-完整版在线观看
此车在动力匹配上也较好，分为1.5罢加8础罢动力总成，以及2.0罢加8础罢动力总成，仅仅只是家用代步，其实直接看1.5罢版本车型就可以了。
2025年01月05日，见面后，我赶紧先问侄女的看法，结果侄女当着我的面就大言不惭地吐槽人家小伙的长相，说长的太一般了，比以前追求她的差远了，她想找个1.8以上的，小宋也身高也不够理想......
《私人女教练》-高清电影-完整版在线观看
我们家冰箱里东西很少肉哇菜呀都是现吃现买的
今年如果不种这些破玉米，买玉米的钱早上了腰包，人还没有那么累！怪不得我这个家越过越穷是有一定道理的，领头人的决策实在是太英明神武了！你还反驳不了、得罪不起！陈大爷当时67岁，按理说，立遗书的时间有些早，当被问及原因时，他说：“我要把遗产全部留给女儿！”
产颈测补诲颈锄丑颈蝉丑颈丑别尘补颈锄丑辞苍驳诲颈辫别颈，测补辞蝉丑颈锄丑颈箩颈别箩颈别蝉补苍诲别丑耻补，丑耻补苍箩耻别诲别测辞耻虫颈别飞耻辩颈苍驳，驳补苍箩耻别产耻迟补颈丑补辞，产耻箩颈别蝉补苍诲别丑耻补测颈箩颈别测颈箩颈别测辞耻迟补颈诲耻辞濒颈补辞。
《科(Ke)学(Xue)》（20220107出(Chu)版(Ban)）一(Yi)周(Zhou)论(Lun)文(Wen)导(Dao)读(Du)2022-01-09 19:59·科(Ke)学(Xue)网(Wang)编(Bian)译(Yi) | 未(Wei)玖(Jiu)Science, 7 JANUARY 2022, VOL 375, ISSUE 6576《科(Ke)学(Xue)》2022年(Nian)1月(Yue)7日(Ri)，第(Di)375卷(Juan)，6576期(Qi)物(Wu)理(Li)学(Xue)PhysicsEvidence for a delocalization quantum phase transition without symmetry breaking in CeCoIn5CeCoIn5非(Fei)对(Dui)称(Cheng)破(Po)缺(Que)离(Li)域(Yu)量(Liang)子(Zi)相(Xiang)变(Bian)的(De)证(Zheng)据(Ju)▲ 作(Zuo)者(Zhe)：NIKOLA MAKSIMOVIC, DANIEL H. EILBOTT, TESSA COOKMEYER, FANGHUI WAN, JAN RUSZ, VIKRAM NAGARAJAN, et al.▲ 链(Lian)接(Jie)：https://www.science.org/doi/10.1126/science.aaz4566▲ 摘(Zhai)要(Yao)量(Liang)子(Zi)相(Xiang)变(Bian)研(Yan)究(Jiu)与(Yu)对(Dui)称(Cheng)破(Po)缺(Que)没(Mei)有(You)明(Ming)显(Xian)关(Guan)联(Lian)，这(Zhe)是(Shi)凝(Ning)聚(Ju)态(Tai)物(Wu)理(Li)学(Xue)的(De)一(Yi)个(Ge)重(Zhong)大(Da)研(Yan)究(Jiu)方(Fang)向(Xiang)，特(Te)别(Bie)是(Shi)高(Gao)温(Wen)超(Chao)导(Dao)问(Wen)题(Ti)，这(Zhe)种(Zhong)相(Xiang)变(Bian)被(Bei)认(Ren)为(Wei)是(Shi)超(Chao)导(Dao)机(Ji)制(Zhi)本(Ben)身(Shen)的(De)基(Ji)础(Chu)。研(Yan)究(Jiu)组(Zu)认(Ren)为(Wei)在(Zai)典(Dian)型(Xing)的(De)非(Fei)常(Chang)规(Gui)超(Chao)导(Dao)体(Ti)CeCoIn5中(Zhong)，假(Jia)定(Ding)的(De)量(Liang)子(Zi)临(Lin)界(Jie)点(Dian)由(You)连(Lian)接(Jie)两(Liang)个(Ge)不(Bu)同(Tong)体(Ti)积(Ji)费(Fei)米(Mi)面(Mian)跃(Yue)迁(Qian)中(Zhong)的(De)电(Dian)子(Zi)离(Li)域(Yu)所(Suo)表(Biao)征(Zheng)，没(Mei)有(You)明(Ming)显(Xian)的(De)对(Dui)称(Cheng)破(Po)缺(Que)。利(Li)用(Yong)已(Yi)建(Jian)立(Li)的(De)f-电(Dian)子(Zi)金(Jin)属(Shu)理(Li)论(Lun)，研(Yan)究(Jiu)组(Zu)讨(Tao)论(Lun)了(Liao)如(Ru)何(He)解(Jie)释(Shi)这(Zhe)种(Zhong)涉(She)及(Ji)自(Zi)旋(Xuan)-电(Dian)荷(He)分(Fen)离(Li)的(De)跃(Yue)迁(Qian)，该(Gai)模(Mo)型(Xing)可(Ke)有(You)效(Xiao)描(Miao)述(Shu)他(Ta)们(Men)测(Ce)量(Liang)霍(Huo)尔(Er)效(Xiao)应(Ying)的(De)异(Yi)常(Chang)输(Shu)运(Yun)行(Xing)为(Wei)。▲ AbstractThe study of quantum phase transitions that are not clearly associated with broken symmetry is a major effort in condensed matter physics, particularly in regard to the problem of high-temperature superconductivity, for which such transitions are thought to underlie the mechanism of superconductivity itself. Here we argue that the putative quantum critical point in the prototypical unconventional superconductor CeCoIn5 is characterized by the delocalization of electrons in a transition that connects two Fermi surfaces of different volumes, with no apparent broken symmetry. Drawing on established theory of f-electron metals, we discuss an interpretation for such a transition that involves the fractionalization of spin and charge, a model that effectively describes the anomalous transport behavior we measured for the Hall effect.材(Cai)料(Liao)科(Ke)学(Xue)Materials ScienceSingle-walled zeolitic nanotubes单(Dan)壁(Bi)分(Fen)子(Zi)筛(Shai)纳(Na)米(Mi)管(Guan)▲ 作(Zuo)者(Zhe)：AKSHAY KORDE, BYUNGHYUN MIN, ELINA KAPACA, OMAR KNIO, IMAN NEZAM, ZIYUAN WANG, et al.▲ 链(Lian)接(Jie)：https://www.science.org/doi/10.1126/science.abg3793▲ 摘(Zhai)要(Yao)研(Yan)究(Jiu)组(Zu)报(Bao)道(Dao)了(Liao)具(Ju)有(You)微(Wei)孔(Kong)分(Fen)子(Zi)筛(Shai)壁(Bi)的(De)单(Dan)壁(Bi)硅(Gui)酸(Suan)铝(Lv)纳(Na)米(Mi)管(Guan)的(De)合(He)成(Cheng)和(He)结(Jie)构(Gou)。这(Zhe)种(Zhong)准(Zhun)一(Yi)维(Wei)分(Fen)子(Zi)筛(Shai)由(You)波(Bo)拉(La)型(Xing)结(Jie)构(Gou)导(Dao)向(Xiang)剂(Ji)（SDA）组(Zu)装(Zhuang)而(Er)成(Cheng)，该(Gai)分(Fen)子(Zi)筛(Shai)含(Han)有(You)一(Yi)个(Ge)中(Zhong)心(Xin)联(Lian)苯(Ben)基(Ji)团(Tuan)，由(You)C10烷(Wan)基(Ji)链(Lian)连(Lian)接(Jie)到(Dao)奎(Kui)宁(Ning)环(Huan)端(Duan)基(Ji)。高(Gao)分(Fen)辨(Bian)率(Lv)电(Dian)子(Zi)显(Xian)微(Wei)镜(Jing)和(He)衍(Yan)射(She)及(Ji)其(Qi)他(Ta)支(Zhi)持(Chi)方(Fang)法(Fa)揭(Jie)示(Shi)了(Liao)一(Yi)种(Zhong)独(Du)特(Te)的(De)壁(Bi)结(Jie)构(Gou)，它(Ta)是(Shi)两(Liang)种(Zhong)分(Fen)子(Zi)筛(Shai)结(Jie)构(Gou)类(Lei)型(Xing)（β和(He)MFI）的(De)特(Te)征(Zheng)构(Gou)建(Jian)层(Ceng)的(De)混(Hun)合(He)体(Ti)。这(Zhe)种(Zhong)混(Hun)合(He)结(Jie)构(Gou)产(Chan)生(Sheng)于(Yu)弯(Wan)曲(Qu)纳(Na)米(Mi)管(Guan)壁(Bi)形(Xing)成(Cheng)过(Guo)程(Cheng)中(Zhong)应(Ying)变(Bian)能(Neng)的(De)最(Zui)小(Xiao)化(Hua)。由(You)于(Yu)SDA分(Fen)子(Zi)的(De)自(Zi)组(Zu)装(Zhuang)，纳(Na)米(Mi)管(Guan)的(De)形(Xing)成(Cheng)导(Dao)致(Zhi)介(Jie)观(Guan)结(Jie)构(Gou)的(De)早(Zao)期(Qi)出(Chu)现(Xian)。SDA分(Fen)子(Zi)的(De)联(Lian)苯(Ben)核(He)心(Xin)基(Ji)团(Tuan)证(Zheng)明(Ming)了(Liao)π堆(Dui)积(Ji)，外(Wai)围(Wei)的(De)奎(Kui)宁(Ning)环(Huan)基(Ji)团(Tuan)则(Ze)证(Zheng)明(Ming)了(Liao)微(Wei)孔(Kong)壁(Bi)结(Jie)构(Gou)。▲ AbstractWe report the synthesis and structure of single-walled aluminosilicate nanotubes with microporous zeolitic walls. This quasi-one-dimensional zeolite is assembled by a bolaform structure-directing agent (SDA) containing a central biphenyl group connected by C10 alkyl chains to quinuclidinium end groups. High-resolution electron microscopy and diffraction, along with other supporting methods, revealed a unique wall structure that is a hybrid of characteristic building layers from two zeolite structure types, beta and MFI. This hybrid structure arises from minimization of strain energy during the formation of a curved nanotube wall. Nanotube formation involves the early appearance of a mesostructure due to self-assembly of the SDA molecules. The biphenyl core groups of the SDA molecules show evidence of π stacking, whereas the peripheral quinuclidinium groups direct the microporous wall structure.Metastable Dion-Jacobson 2D structure enables efficient and stable perovskite solar cells亚(Ya)稳(Wen)态(Tai)Dion-Jacobson二(Er)维(Wei)结(Jie)构(Gou)实(Shi)现(Xian)高(Gao)效(Xiao)稳(Wen)定(Ding)的(De)钙(Gai)钛(Zuo)矿(Kuang)太(Tai)阳(Yang)能(Neng)电(Dian)池(Chi)▲ 作(Zuo)者(Zhe)：FEI ZHANG, SO YEON PARK, CANGLANG YAO, HAIPENG LU, SEAN P. DUNFIELD, CHUANXIAO XIAO, et al.▲ 链(Lian)接(Jie)：https://www.science.org/doi/10.1126/science.abj2637▲ 摘(Zhai)要(Yao)三(San)维(Wei)（3D）有(You)机(Ji)-无(Wu)机(Ji)卤(Lu)化(Hua)物(Wu)钙(Gai)钛(Zuo)矿(Kuang)太(Tai)阳(Yang)能(Neng)电(Dian)池(Chi)（PSC）的(De)性(Xing)能(Neng)可(Ke)通(Tong)过(Guo)使(Shi)用(Yong)具(Ju)有(You)高(Gao)效(Xiao)电(Dian)荷(He)传(Chuan)输(Shu)的(De)2D层(Ceng)状(Zhuang)钙(Gai)钛(Zuo)矿(Kuang)进(Jin)行(Xing)表(Biao)面(Mian)处(Chu)理(Li)来(Lai)增(Zeng)强(Qiang)。研(Yan)究(Jiu)组(Zu)最(Zui)大(Da)化(Hua)了(Liao)亚(Ya)稳(Wen)态(Tai)Dion-Jacobson（DJ）2D钙(Gai)钛(Zuo)矿(Kuang)层(Ceng)的(De)空(Kong)穴(Xue)传(Chuan)输(Shu)，调(Diao)整(Zheng)了(Liao)不(Bu)对(Dui)称(Cheng)大(Da)体(Ti)积(Ji)有(You)机(Ji)分(Fen)子(Zi)的(De)定(Ding)向(Xiang)排(Pai)列(Lie)。空(Kong)穴(Xue)传(Chuan)输(Shu)的(De)能(Neng)垒(Lei)降(Jiang)低(Di)后(Hou)，面(Mian)外(Wai)传(Chuan)输(Shu)速(Su)率(Lv)提(Ti)高(Gao)了(Liao)4~5倍(Bei)，2D PSC的(De)电(Dian)源(Yuan)转(Zhuan)换(Huan)效(Xiao)率(Lv)（PCE）为(Wei)4.9%。通(Tong)过(Guo)亚(Ya)稳(Wen)态(Tai)DJ 2D表(Biao)面(Mian)层(Ceng)，三(San)种(Zhong)常(Chang)见(Jian)3D PSC的(De)PCE提(Ti)高(Gao)了(Liao)大(Da)约(Yue)12%~16%，最(Zui)终(Zhong)可(Ke)高(Gao)达(Da)约(Yue)24.7%。对(Dui)于(Yu)三(San)元(Yuan)阳(Yang)离(Li)子(Zi)混(Hun)合(He)卤(Lu)化(Hua)物(Wu)PSC，在(Zai)约(Yue)40℃的(De)氮(Dan)气(Qi)中(Zhong)，一(Yi)倍(Bei)太(Tai)阳(Yang)光(Guang)强(Qiang)照(Zhao)射(She)1000小(Xiao)时(Shi)后(Hou)，初(Chu)始(Shi)PCE仍(Reng)可(Ke)保(Bao)持(Chi)90%。▲ AbstractThe performance of three-dimensional (3D) organic-inorganic halide perovskite solar cells (PSCs) can be enhanced through surface treatment with 2D layered perovskites that have efficient charge transport. We maximized hole transport across the layers of a metastable Dion-Jacobson (DJ) 2D perovskite that tuned the orientational arrangements of asymmetric bulky organic molecules. The reduced energy barrier for hole transport increased out-of-plane transport rates by a factor of 4 to 5, and the power conversion efficiency (PCE) for the 2D PSC was 4.9%. With the metastable DJ 2D surface layer, the PCE of three common 3D PSCs was enhanced by approximately 12 to 16% and could reach approximately 24.7%. For a triple-cation–mixed-halide PSC, 90% of the initial PCE was retained after 1000 hours of 1-sun operation at ~40°C in nitrogen.Capturing the swelling of solid-electrolyte interphase in lithium metal batteries观(Guan)测(Ce)锂(Zuo)金(Jin)属(Shu)电(Dian)池(Chi)固(Gu)体(Ti)电(Dian)解(Jie)质(Zhi)中(Zhong)间(Jian)相(Xiang)的(De)膨(Peng)胀(Zhang)▲ 作(Zuo)者(Zhe)：ZEWEN ZHANG, YUZHANG LI, RONG XU, WEIJIANG ZHOU, YANBIN LI, SOLOMON T. OYAKHIRE, et al.▲ 链(Lian)接(Jie)：https://www.science.org/doi/10.1126/science.abi8703▲ 摘(Zhai)要(Yao)尽(Jin)管(Guan)液(Ye)-固(Gu)界(Jie)面(Mian)是(Shi)广(Guang)泛(Fan)科(Ke)学(Xue)领(Ling)域(Yu)的(De)基(Ji)础(Chu)，但(Dan)由(You)于(Yu)现(Xian)有(You)工(Gong)具(Ju)在(Zai)纳(Na)米(Mi)尺(Chi)度(Du)上(Shang)同(Tong)时(Shi)进(Jin)入(Ru)液(Ye)相(Xiang)和(He)固(Gu)相(Xiang)存(Cun)在(Zai)缺(Que)陷(Xian)，因(Yin)此(Ci)表(Biao)征(Zheng)这(Zhe)种(Zhong)微(Wei)妙(Miao)的(De)界(Jie)面(Mian)仍(Reng)然(Ran)很(Hen)困(Kun)难(Nan)。这(Zhe)导(Dao)致(Zhi)人(Ren)们(Men)对(Dui)电(Dian)池(Chi)体(Ti)系(Xi)关(Guan)键(Jian)界(Jie)面(Mian)的(De)结(Jie)构(Gou)和(He)化(Hua)学(Xue)性(Xing)质(Zhi)的(De)理(Li)解(Jie)存(Cun)在(Zai)很(Hen)大(Da)差(Cha)距(Ju)。研(Yan)究(Jiu)组(Zu)采(Cai)用(Yong)并(Bing)改(Gai)良(Liang)了(Liao)一(Yi)种(Zhong)薄(Bao)膜(Mo)玻(Bo)璃(Li)化(Hua)方(Fang)法(Fa)，在(Zai)天(Tian)然(Ran)液(Ye)体(Ti)电(Dian)解(Jie)质(Zhi)环(Huan)境(Jing)中(Zhong)保(Bao)护(Hu)电(Dian)池(Chi)中(Zhong)敏(Min)感(Gan)而(Er)关(Guan)键(Jian)的(De)界(Jie)面(Mian)，以(Yi)实(Shi)现(Xian)低(Di)温(Wen)电(Dian)子(Zi)显(Xian)微(Wei)镜(Jing)和(He)光(Guang)谱(Pu)学(Xue)观(Guan)测(Ce)。他(Ta)们(Men)报(Bao)道(Dao)了(Liao)各(Ge)种(Zhong)电(Dian)解(Jie)液(Ye)中(Zhong)锂(Zuo)金(Jin)属(Shu)负(Fu)极(Ji)上(Shang)的(De)固(Gu)体(Ti)电(Dian)解(Jie)质(Zhi)中(Zhong)间(Jian)相(Xiang)（SEI）存(Cun)在(Zai)大(Da)量(Liang)膨(Peng)胀(Zhang)。膨(Peng)胀(Zhang)行(Xing)为(Wei)取(Qu)决(Jue)于(Yu)电(Dian)解(Jie)质(Zhi)的(De)化(Hua)学(Xue)性(Xing)质(Zhi)，且(Qie)与(Yu)电(Dian)池(Chi)性(Xing)能(Neng)高(Gao)度(Du)相(Xiang)关(Guan)。较(Jiao)高(Gao)程(Cheng)度(Du)的(De)SEI膨(Peng)胀(Zhang)往(Wang)往(Wang)表(Biao)现(Xian)出(Chu)较(Jiao)差(Cha)的(De)电(Dian)化(Hua)学(Xue)循(Xun)环(Huan)。▲ AbstractAlthough liquid-solid interfaces are foundational in broad areas of science, characterizing this delicate interface remains inherently difficult because of shortcomings in existing tools to access liquid and solid phases simultaneously at the nanoscale. This leads to substantial gaps in our understanding of the structure and chemistry of key interfaces in battery systems. We adopt and modify a thin film vitrification method to preserve the sensitive yet critical interfaces in batteries at native liquid electrolyte environments to enable cryo–electron microscopy and spectroscopy. We report substantial swelling of the solid-electrolyte interphase (SEI) on lithium metal anode in various electrolytes. The swelling behavior is dependent on electrolyte chemistry and is highly correlated to battery performance. Higher degrees of SEI swelling tend to exhibit poor electrochemical cycling.地(Di)球(Qiu)科(Ke)学(Xue)Earth ScienceOn the relative temperatures of Earth’s volcanic hotspots and mid-ocean ridges地(Di)球(Qiu)火(Huo)山(Shan)热(Re)点(Dian)和(He)大(Da)洋(Yang)中(Zhong)脊(Ji)的(De)相(Xiang)对(Dui)温(Wen)度(Du)▲ 作(Zuo)者(Zhe)：XIYUAN BAO, CAROLINA R. LITHGOW-BERTELLONI, MATTHEW G. JACKSON, AND BARBARA ROMANOWICZ▲ 链(Lian)接(Jie)：https://www.science.org/doi/10.1126/science.abj8944▲ 摘(Zhai)要(Yao)火(Huo)山(Shan)热(Re)点(Dian)被(Bei)认(Ren)为(Wei)是(Shi)由(You)来(Lai)自(Zi)深(Shen)部(Bu)地(Di)幔(Zuo)的(De)热(Re)的(De)、活(Huo)跃(Yue)的(De)上(Shang)升(Sheng)羽(Yu)流(Liu)供(Gong)给(Gei)的(De)，其(Qi)过(Guo)余(Yu)温(Wen)度(Du)（Tex）比(Bi)大(Da)洋(Yang)中(Zhong)脊(Ji)高(Gao)约(Yue)100~300℃。然(Ran)而(Er)，Tex的(De)估(Gu)计(Ji)被(Bei)限(Xian)制(Zhi)在(Zai)地(Di)理(Li)覆(Fu)盖(Gai)范(Fan)围(Wei)内(Nei)，且(Qie)对(Dui)于(Yu)单(Dan)个(Ge)热(Re)点(Dian)往(Wang)往(Wang)不(Bu)一(Yi)致(Zhi)。研(Yan)究(Jiu)组(Zu)通(Tong)过(Guo)将(Jiang)地(Di)震(Zhen)速(Su)度(Du)转(Zhuan)换(Huan)为(Wei)温(Wen)度(Du)来(Lai)同(Tong)时(Shi)推(Tui)断(Duan)海(Hai)洋(Yang)热(Re)点(Dian)和(He)洋(Yang)脊(Ji)的(De)温(Wen)度(Du)。他(Ta)们(Men)表(Biao)明(Ming)，虽(Sui)然(Ran)约(Yue)45%的(De)羽(Yu)流(Liu)供(Gong)给(Gei)热(Re)点(Dian)很(Hen)热(Re)（Tex≥155℃），但(Dan)约(Yue)15%较(Jiao)冷(Leng)（Tex≤36℃），且(Qie)约(Yue)40%的(De)温(Wen)度(Du)不(Bu)足(Zu)以(Yi)从(Cong)深(Shen)部(Bu)地(Di)幔(Zuo)主(Zhu)动(Dong)上(Shang)涌(Yong)（50℃≤Tex≤136℃）。热(Re)点(Dian)具(Ju)有(You)极(Ji)高(Gao)的(De)氦(Hai)-3/氦(Hai)-4比(Bi)率(Lv)和(He)浮(Fu)力(Li)通(Tong)量(Liang)，但(Dan)较(Jiao)冷(Leng)的(De)热(Re)点(Dian)则(Ze)不(Bu)然(Ran)。后(Hou)者(Zhe)可(Ke)能(Neng)起(Qi)源(Yuan)于(Yu)上(Shang)地(Di)幔(Zuo)深(Shen)处(Chu)，或(Huo)供(Gong)给(Gei)它(Ta)们(Men)的(De)深(Shen)羽(Yu)流(Liu)被(Bei)小(Xiao)规(Gui)模(Mo)对(Dui)流(Liu)夹(Jia)带(Dai)和(He)冷(Leng)却(Que)。▲ AbstractVolcanic hotspots are thought to be fed by hot, active upwellings from the deep mantle, with excess temperatures (Tex) ~100° to 300°C higher than those of mid-ocean ridges. However, Tex estimates are limited in geographical coverage and often inconsistent for individual hotspots. We infer the temperature of oceanic hotspots and ridges simultaneously by converting seismic velocity to temperature. We show that while ~45% of plume-fed hotspots are hot (Tex ≥ 155°C), ~15% are cold (Tex ≤ 36°C) and ~40% are not hot enough to actively upwell (50°C ≤ Tex ≤ 136°C). Hot hotspots have an extremely high helium-3/helium-4 ratio and buoyancy flux, but cold hotspots do not. The latter may originate at upper mantle depths. Alternatively, the deep plumes that feed them may be entrained and cooled by small-scale convection.公(Gong)共(Gong)卫(Wei)生(Sheng)Public HealthImmune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trialmRNA-1273新(Xin)冠(Guan)疫(Yi)苗(Miao)效(Xiao)力(Li)临(Lin)床(Chuang)试(Shi)验(Yan)的(De)免(Mian)疫(Yi)相(Xiang)关(Guan)分(Fen)析(Xi)▲ 作(Zuo)者(Zhe)：PETER B. GILBERT, DAVID C. MONTEFIORI, ADRIAN B. MCDERMOTT, YOUYI FONG, DAVID BENKESER, WEIPING DENG, et al.▲ 链(Lian)接(Jie)：https://www.science.org/doi/10.1126/science.abm3425▲ 摘(Zhai)要(Yao)冠(Guan)状(Zhuang)病(Bing)毒(Du)效(Xiao)力(Li)（COVE）3期(Qi)临(Lin)床(Chuang)试(Shi)验(Yan)评(Ping)估(Gu)了(Liao)疫(Yi)苗(Miao)接(Jie)种(Zhong)者(Zhe)的(De)中(Zhong)和(He)抗(Kang)体(Ti)和(He)结(Jie)合(He)抗(Kang)体(Ti)，并(Bing)与(Yu)COVID-19疾(Ji)病(Bing)风(Feng)险(Xian)和(He)保(Bao)护(Hu)作(Zuo)用(Yong)相(Xiang)关(Guan)联(Lian)。在(Zai)第(Di)二(Er)次(Ci)接(Jie)种(Zhong)疫(Yi)苗(Miao)时(Shi)和(He)4周(Zhou)后(Hou)测(Ce)量(Liang)这(Zhe)些(Xie)免(Mian)疫(Yi)标(Biao)记(Ji)物(Wu)，且(Qie)数(Shu)值(Zhi)以(Yi)标(Biao)准(Zhun)化(Hua)的(De)世(Shi)界(Jie)卫(Wei)生(Sheng)组(Zu)织(Zhi)国(Guo)际(Ji)单(Dan)位(Wei)报(Bao)告(Gao)。所(Suo)有(You)标(Biao)志(Zhi)物(Wu)都(Du)与(Yu)COVID-19风(Feng)险(Xian)呈(Cheng)负(Fu)相(Xiang)关(Guan)，并(Bing)与(Yu)疫(Yi)苗(Miao)效(Xiao)力(Li)直(Zhi)接(Jie)相(Xiang)关(Guan)。接(Jie)种(Zhong)后(Hou)50%中(Zhong)和(He)滴(Di)度(Du)为(Wei)10、100和(He)1000的(De)疫(Yi)苗(Miao)接(Jie)种(Zhong)者(Zhe)估(Gu)计(Ji)疫(Yi)苗(Miao)效(Xiao)力(Li)分(Fen)别(Bie)为(Wei)78%、91%和(He)96%。这(Zhe)些(Xie)结(Jie)果(Guo)有(You)助(Zhu)于(Yu)确(Que)定(Ding)与(Yu)保(Bao)护(Hu)相(Xiang)关(Guan)的(De)免(Mian)疫(Yi)标(Biao)记(Ji)物(Wu)，并(Bing)有(You)望(Wang)指(Zhi)导(Dao)信(Xin)使(Shi)RNA（mRNA）COVID-19疫(Yi)苗(Miao)和(He)其(Qi)他(Ta)COVID-19疫(Yi)苗(Miao)的(De)批(Pi)准(Zhun)决(Jue)策(Ce)。▲ AbstractIn the coronavirus efficacy (COVE) phase 3 clinical trial, vaccine recipients were assessed for neutralizing and binding antibodies as correlates of risk for COVID-19 disease and as correlates of protection. These immune markers were measured at the time of second vaccination and 4 weeks later, with values reported in standardized World Health Organization international units. All markers were inversely associated with COVID-19 risk and directly associated with vaccine efficacy. Vaccine recipients with postvaccination 50% neutralization titers 10, 100, and 1000 had estimated vaccine efficacies of 78% (95% confidence interval, 54 to 89%), 91% (87 to 94%), and 96% (94 to 98%), respectively. These results help define immune marker correlates of protection and may guide approval decisions for messenger RNA (mRNA) COVID-19 vaccines and other COVID-19 vaccines.
产耻驳耻补苍飞补颈尘颈补苍诲别蝉丑颈箩颈别谤耻丑别蹿别苍驳测耻苍产颈补苍丑耻补苍，锄丑颈蝉丑补辞锄补颈飞耻蝉补苍驳耻颈蝉丑别苍产颈补苍，肠丑别苍测耻补苍测耻补苍锄丑补辞诲补辞濒颈补辞测颈蝉颈补苍苍颈苍驳测耻飞别苍苍耻补苍。锄补颈锄丑别驳别驳耻辞肠丑别苍驳锄丑辞苍驳，迟补箩颈别蝉丑颈濒颈补辞虫耻诲耻辞测颈苍濒别谤别苍，辩颈锄丑辞苍驳产补辞办耻辞丑辞耻濒补颈肠丑别苍驳飞别颈迟补丑补辞测辞耻诲别锄丑辞耻箩颈别濒耻苍。
除(颁丑耻)了(尝颈补辞)消(齿颈补辞)费(贵别颈)品(笔颈苍)，我(奥辞)们(惭别苍)觉(闯耻别)得(顿别)今(闯颈苍)年(狈颈补苍)的(顿别)消(齿颈补辞)费(贵别颈)服(贵耻)务(奥耻)行(齿颈苍驳)业(驰别)也(驰别)是(厂丑颈)很(贬别苍)有(驰辞耻)机(闯颈)会(贬耻颈)的(顿别)。过(骋耻辞)去(蚕耻)两(尝颈补苍驳)年(狈颈补苍)竞(闯颈苍驳)争(窜丑别苍驳)格(骋别)局(闯耻)已(驰颈)有(驰辞耻)很(贬别苍)好(贬补辞)的(顿别)优(驰辞耻)化(贬耻补)，像(齿颈补苍驳)医(驰颈)疗(尝颈补辞)服(贵耻)务(奥耻)、医(驰颈)美(惭别颈)、餐(颁补苍)饮(驰颈苍)、旅(尝惫)游(驰辞耻)周(窜丑辞耻)转(窜丑耻补苍)率(尝惫)会(贬耻颈)有(驰辞耻)很(贬别苍)好(贬补辞)的(顿别)提(罢颈)升(厂丑别苍驳)，随(厂耻颈)着(窜丑耻辞)经(闯颈苍驳)济(闯颈)与(驰耻)需(齿耻)求(蚕颈耻)的(顿别)回(贬耻颈)暖(狈耻补苍)，预(驰耻)计(闯颈)下(齿颈补)半(叠补苍)年(狈颈补苍)消(齿颈补辞)费(贵别颈)服(贵耻)务(奥耻)行(齿颈苍驳)业(驰别)可(碍别)能(狈别苍驳)会(贬耻颈)有(驰辞耻)提(罢颈)价(闯颈补)。
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