和平精英可以看到胸吗 - 电玩兔
两人静静地坐着,听着海浪一遍遍拍打在岸边,那种恒久和平静,让之前的波澜渐行渐远。李晓芬感到一种莫名的释然,仿佛放下了一个不属于自己的负担,她意识到,信任与理解才是她们婚姻里最宝贵的珠宝。
2025年01月10日,家里蚊子太多?只需要一瓶啤酒,夏天不用蚊香,从此不再忍受蚊子
和平精英可以看到胸吗 - 电玩兔
浙江新能(600032)4月18日晚间公告为拓展可再生能源发电项目公司控股子公司绿能电力拟与浦江城投共同设立浙江浙能浦江抽水蓄能有限公司其中绿能电力以现金方式认缴出资10.4亿元占股65%
动员全社会全面投入流感大流行的防控工作,并对全市卫生应急资源实施统一管理和调配。全市各级各部门按照市应急指挥部的部署落实各项疫情防控措施。最后,郑某某又向法院申请强制执行,可打定主意不还钱的黄老赖,根本就不管,依然死不要脸到底。哪怕被法院司法拘留,他也依然不还钱。
箩颈补苍锄补辞测耻蹿耻测颈:2004苍颈补苍8测耻别1谤颈蝉丑补苍驳丑补颈丑耻诲辞苍驳锄补辞肠丑耻补苍肠丑补苍驳虫颈补蝉丑耻颈,2005苍颈补苍9测耻别谤耻濒颈别丑补颈箩耻苍,濒颈蝉丑耻产别颈丑补颈箩颈补苍诲耻颈。别谤虫颈谤别苍苍别,肠辞苍驳虫颈补辞锄补颈箩颈补蹿耻箩颈苍测颈测耻蝉丑颈,蝉丑颈尘别驳补辞箩颈诲辞苍驳虫颈尘别颈箩颈补苍驳耻辞,测补驳别苍产耻诲补苍驳丑耻颈蝉丑颈。
2024-07-15 17:59·中(Zhong)国(Guo)质(Zhi)量(Liang)新(Xin)闻(Wen)
zonglichengshu:1331gonglilinbaliu | WHOdi5banlinbazuzhizhongliufenlei(zhongyingduizhaozuiquanzuishiyong)yuanchuang2023-07-05 20:58·zhongliuzhuankeyisheng2022nianshijieweishengzuzhi(WHO)fabudi5banzaoxueyulinbazuzhizhongliufenlei(WHO-HAEM5)The 5th edition of the WHO Calssification of Haematolymphoid Tumorsyi、suixizengzhihezhongliubaokuokelongxingzaoxue、gusuizengzhixingzhongliu(manxingsuixibaobaixuebing、manxingzhongxinglixibaobaixuebingdeng)、gusuizengshengyichangzhongliu(MDS)、jixingsuixibaixuebing(AML)dengdeng,tongchangguishuxueyeneike。er、shutuxibao/zuzhixibaozhongliushutuxibao/zuzhixibaozhongliuzaixinbanfenleitixizhongdingweiyusuixizhongliuzhihou,tongchangrenweitamenqiyuanxiangjin,qiyuanyuchangjiandesuixizuxibao(chanshengdanhexibao/zuzhixibao/shutuxibaopuxi),disibanfenleizhong“zuzhixibao/shutuxibaozhongliu”xiade“lvpaoshutuxibaorouliu”、“xianweimuxibaowangzhuangxibaozhongliu”shiyoulinbajizhixibaochanshengdezhongliu,diwubanfenleijiangqifenchulaiguidao“linbazuzhijianzhiyuanxingzhongliu”xia。san、Bxibaolinbazengzhixingjibinghezhongliusi、TheNKxibaolinbazengzhixingjibinghezhongliuwu、linbazuzhijianzhiyuanxingzhongliu(xinyinrufenlei)shuyulinxizhongliu(linbazuzhizhongliu),benwenzhuyaoshejizhesanbufenneirong。liu、yichuanzhongliuzonghezheng(xinyinruzhangjie)yichuanzhongliuzonghezhengbaokuoyihuansuixizhongliuhelinxizhongliuxiangguandezonghezheng。yichuanxingzhongliuzonghezheng(yichuanyiganzonghezheng)xixinyinrudefenlei,baokuofankenipinxue(Fanconipinxue)、bulumuzonghezheng(Bloomzonghezheng,mianbuhongbanzuoruzonghezheng)、gongjishidiaomaoxixueguankuozhangzonghezheng(AT)、RASbing(RASzonghezheng)、Nijmegen-Breakagezonghezheng(Nijmegenduanliezonghezheng,Nijmegen breakage syndrome,NBS)deng。yihuansuixizhongliudeyichuanxingzhongliuzonghezheng:Fanconipinxue、RASbingdeng,ATheNBSzeyulinxizhongliuyouweixiangguan,fenbieyuATMheNBNpeixitubianxiangguan。guanyudi5banfenleidejidianzhongyaoshuoming:1、jibingfencengmuluhejiegouzunzhaoguigejibiedizengdeshunxu,yimuliaoran:leibiecategory(biru:chengshuBxibaolinbaliu)、jiazu/zhongleifamily/class(biru:daBxibaolinbaliu)、shiti/leixingentity/type(biru:mimanxingdaBxibaolinbaliu、feitezhixing)heyaxingsubtype(biru:mimanxingda B xibaolinbaliu,feitezhixing,shengfazhongxinBxibaoyang)。2、jibingfenleizunzhaoxibaopuxideshunxu(puxideguishuyijuliushixibaoshuhe/huomianyizuhuademianyibiaoxingfenxi),xianshiqiantixibaozhongliu,ranhoushichengshuexingzhongliu。zaiyigejiazu/zhonglei(family/class)zhong,shiti/leixing(entity/type)tongchangancongduoxingdaoqinxixingshunxupailie。3、linbaliuyangjibing(yejiushiyulinbaliulinchuangtezhengxiangsidejibing)yijixuyaojianbiedefeizhongliujibingshoucinarufenleizhong,youzhuyufangzhilinbaliuguoduzhenduanbingtigaoduilinchuangbinglixuebutongjibingleixingdeshibie。4、yinrupeixizhongliuyiganzonghezhengzuoweizhuanmendedanjie,yitixianqiriyizengjiadelinchuangzhongyaoxing,zhexiezonghezhengtongchangyusuixihuolinxizhongliuxiangguan。5、duixiantianxing(yuanfaxing)mianyiquexianhehuodexing(jifaxing)mianyijibingxiangguandelinbazengzhiyeyouxindefaxian,duizhexiegengxindeneirongyebaohanzaidiwubanxinfenleizhong。2022 niandiwuban WHO linbazuzhizhongliufenlei:zaoxueyulinbazuzhizhongliufenlei (WHO-HAEM5)linxizhongliubufen:The 5th edition of the WHO Calssification of Haematolymphoid Tumors-Lymphoid Neoplasmaslinbazuzhizhongliu(heji125geshiti/leixing)yi、Bxibaolinbazengzhixingjibinghezhongliu(3leibie,79geshiti/leixing)1、Bxibaoweizhudezhongliuyangbingbian(5ge)2、qiantiBxibaozhongliu(13ge)3、chengshuBxibaozhongliu(49ge)4、jiangxibaozhongliujiqitajuyoufudanbaidejibing(12ge)er、TheNKxibaolinbazengzhixingjibinghezhongliu(3leibie,39geshiti/leixing)1、Txibaoweizhudezhongliuyangbingbian(3ge)2、qiantiTxibaozhongliu(2ge)3、chengshuTheNKxibaozhongliu(34ge)san、linbazuzhijianzhiyuanxingzhongliu(7geshiti/leixing)xiabiaozhongzuocebian2022niandiwubanWHO-HAEM5fenlei(linxi),youcewei2017niandisibanxiudingWHO-HAEM4Rfenlei(linxi)。zhu:lymphoproliferative disorder(LPD),linba(zuzhi)zengshengxingjibing,linba(zuzhi)zengzhixingjibing。BxibaolinbazengzhixingjibinghezhongliuB-cell lymphoid proliferations and lymphomas(79geshiti/leixing)Bxibaoweizhuzhongliuyangbingbian(5geshiti/leixing)Tumor-like lesions with B-cell predominancediwubanfenleidisiban(xiuding)fenleiyulinbaliuxiangsi(linbaliuyang)fanyingxingfuhanBxibaodelinbaxibaozengzhijibing(fuhanBxibaodefanyingxinglinbayangzengsheng,kemonilinbaliu)?Reactive B-cell rich lymphoid proliferations that can mimic lymphomawu(disibanweilieru,bubaokuozainei,xiatong)IgG4xiangguanjibing?IgG4-related diseasewudanzhongxinCastlemanbing?Unicentric Castleman disease(UCD)wutefaxingduozhongxinCastlemanbing(tefaxingMCD)?Idiopathic multicentric Castleman diseasewuKSHV/HHV8 xiangguandeduozhongxinCastlemanbing(KSHV/HHV8xiangguandeMCD)?KSHV/HHV8-associated multicenrtric Castleman diseaseduozhongxinCastlemanbing(MCD)【zhu】Bxibaoweizhuzhongliuyangbingbianxidiwubanxinyinrudefenlei,baokuo5gebutongdejibingshiti/leixing:(1)yiBxibaoweizhudefeizhongliuxinglinbaxibaozengsheng(shejilinbajiehe/huojiewaibuwei),yulinbaliuxiangsi(linbaliuyang),yechengweifuhanBxibaodefanyingxinglinbayangzengsheng,kemonilinbaliu?。gaileijibingbaokuo:shengfazhongxindejinxingxingzhuanhua、chuandan(chuanranxingdanhexibaozengduozheng)、nvxingshengzhidaodecaihuayangfanyingxinglinbazuzhizengsheng/linbaliuyangbingbian、xitongxinghongbanlangchuang。(2)IgG4xiangguanjibing?:IgG4xiangguanlinbajiezhongdajuyouyuCastlemanbingxiangzhongdiedetezheng。(3)Castlemanbingbaokuosanzhongleixing:danzhongxinCastlemanbing?、tefaxingduozhongxinCastlemanbing?、KSHV/HHV8 xiangguandeduozhongxinCastlemanbing?,tamendelinchuanghebinglixuetezhengbutong。qiantiBxibaozhongliu(13geshiti/leixing)Precursor B-cell neoplasmsji:yuanshiBlinbaxibaobaixuebing/linbaliu(Blinbaxibaobaixuebing/linbaliu,Blinbamuxibaobaixuebing/linbaliu,B-cell lymphoblastic leukaemias/lymphomas,B-ALL/LBL):(1)Blinbamuxibaobaixuebing/linbaliu,feitezhixing(B-ALL/LBL,NOS)(2)bandingyiyichuanxueyichangdeBlinbaxibaobaixuebing/linbamuxibaolinbaliu(12ge)diwubanfenleidisiban(xiuding)fenleiBlinbaxibaobaixuebing/linbaliu,feitezhixing(B-ALL/LBL,NOS)?B-cell lymphoblastic leukaemia/lymphoma,NOSxiangtongbandingyiyichuanxueyichangdeBlinbaxibaobaixuebing/linbamuxibaolinbaliu(12zhong)Blinbaxibaobaixuebing/linbaliu(B-ALL/LBL),bangaochaoerbeiti?B-ALL/LBL with high hyperdiploidyBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),banchaoerbeitiBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),banyaerbeiti(dierbeiti)?B-ALL/LBL with hypodiploidyxiangtongBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),baniAMP21?B-ALL/LBL with iAMP21xiangtongBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban BCR::ABL1 ronghe?B-ALL/LBL with BCR::ABL1 fusionBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL)bant(9;22)(q34;q11.2); BCR-ABL1rongheBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban BCR::ABL1 yangtezheng?B-ALL/LBL with BCR::ABL1-like featuresBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL), banBCR-ABL1 yangBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban KMT2A zhongpai?B-ALL/LBL with KMT2A rearrangementBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban t(v;11q23.3); KMT2AzhongpaiBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban ETV6::RUNX1 ronghe?B-ALL/LBL with ETV6::RUNX1 fusionBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban t(12;21)(p13.2;q22.1); ETV6-RUNX1rongheBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban ETV6::RUNX1yangtezheng?B-ALL/LBL with ETV6::RUNX1-like featureswuBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban TCF3::PBX1 ronghe?B-ALL/LBL with TCF3::PBX1 fusionBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban t(1;19)(q23;p13.3); TCF3-PBX1rongheBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban IGH::IL3 ronghe?B-ALL/LBL with IGH::IL3 fusionBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban t(5;14)(q31.1;q32.1); IGH/IL3rongheBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban TCF3::HLF ronghe?B-ALL/LBL with TCF3::HLF fusionwuBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),banqitatedingyichuanxueyichang?B-ALL/LBL with other defined genetic abnormalitiesxiangtong【zhu】B-ALL/LBLfabingjizhizaidaduoshuqingkuangxiacunzaiyizhidequdongyinsu,baokuoiAMP21、BCR::ABL1 ronghe、 KMT2A zhongpai、ETV6::RUNX1 ronghe、TCF3::PBX1 ronghe、 IGH::IL3 ronghe、TCF3::HLF ronghedeng。genjuransetishumubianhua(chaoerbeiti、yaerbeitideng)、ransetizhongpaihuocunzaiqitayichuanqudongyinsuerguiweibutongdeyaxing?-?。genjurenleijiyinzuzuzhijiyinmingmingweiyuanhuijianyi,caiyongshuangmaohao(::)biaojironghejiyinxinmingcheng。chucizhiwaijibianjingguoquanmianjianceyerengranwufafenleideyileijibingzeguiweiBlinbaxibaobaixuebing/linbamuxibaolinbaliu,feitezhixing(B-ALL/LBL,NOS)?chengshuBxibaozhongliu(12gejiazu/zhonglei,49geshiti/leixing)Mature B-cell neoplasms(1)zhongliuqianqihezhongliuxingxiaolinbaxibaozengzhi(2ge)(2)piBxibaolinbaliuhebaixuebing(4ge)(3)linbajiangxibaolinbaliu(1ge)(4)bianyuanqulinbaliu(4ge)(5)lvpaoxinglinbaliu(4ge)(6)pifulvpaozhongxinlinbaliu(1ge)(7)taoxibaolinbaliu(3ge)(8)duoxingBxibaolinbaliudezhuanhua(1ge)(9)daBxibaolinbaliu(18ge)(10)bojitelinbaliu(1ge)(11)KSHV/HHV8xiangguanBxibaolinbazengzhixingjibinghelinbaliu(3ge)(12)yumianyiquexianheshidiaoxiangguandelinbazengzhihelinbaliu(5ge)(13)huoqijinlinbaliu(2ge)diwubanfenleidisiban(xiuding)fenleizhongliuqianqihezhongliuxingxiaolinbaxibaozengzhiPre-neoplastic and neoplastic small lymphocytic proliferationsdankelong B linbaxibaozengduozheng(MBL)?Monoclonal B-cell lymphocytosisxiangtongmanxinglinbaxibaobaixuebing/xiaolinbaxibaolinbaliu(CLL/SLL)?Chronic lymphocytic leukaemia/small lymphocytic lymphomaxiangtongB-PLLbingmingbeishanchu(buzaishiweiyigejibingleixing)Bxibaoyoulinbaxibaobaixuebing(B-PLL)B-prolymphocytic leukemiapiBxibaolinbaliuhebaixuebingSplenic B-cell lymphomas and leukaemiasmaoxibaobaixuebing(HCL)?Hairy cell leukaemiaxiangtongpibianyuanqulinbaliu(SMZL)?Splenic marginal zone lymphomaxiangtongpimimanxinghongsuixiaoBxibaolinbaliu(SDRPL)?Splenic diffuse red pulp small B-cell lymphomaxiangtongpiBxibaolinbaliu/baixuebing,banxianzhuheren(SBLPN)?Splenic B-cell lymphoma/leukaemia with prominent nucleoliweibaokuozainei,wucibingming(disibanbingmingshuyuwei:maoxibaobaixuebingbianyixingheCD5yinxingBxibaoyoulinbaxibaobaixuebing)linbajiangxibaolinbaliuLymphoplasmacytic lymphomalinbajiangxibaolinbaliu(LPL)?Lymphoplasmacytic lymphomaxiangtong【zhu】baokuoliangzhongyaxing:IgM-LPL/WM(zuichangjian,yuezhan95%):IgM-LPL/Waldenstromjuqiudanbaixuebing(WM,huashijuqiudanbaixuezheng);feiWMxingLPL(yuezhan5%)。bianyuanqulinbaliuMarginal zone lymphomazhanmoxiangguanlinbazuzhijiewaibianyuanqulinbaliu)(MALT)?Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissuexiangtongyuanfaxingpifubianyuanqulinbaliu(PCMZL)?Primary cutaneous marginal zone lymphomaweidanduliechu(guiruzhanmoxiangguanlinbazuzhijiewaibianyuanqulinbaliu)linbajiebianyuanqulinbaliu(NMZL)?Nodal marginal zone lymphomaxiangtongertong(linbajie)bianyuanqulinbaliu(pNMZL)?Paediatric (nodal) marginal zone lymphomaxiangtong【zhu】jiepobuweibutong,xibaoyichuanxuehejiyintubianpubutong。(1)linbajiebianyuanqulinbaliu(NMZL)hejiewaibianyuanqulinbaliu(EMZL)jiyintubianpubutong。(2)jiewaiMZL(EMZL)changjiandebaokuowei、fei、yanfushuqi、tuoyexian、jiazhuangxian、pifudengbuweideMZL,butongdejiewaiMZLzhijiancunzaixianzhudeyichuanxuechayi。(3)pifuMZLjuyoudutedelinchuangbinglitezheng,qubieyuqitajiewaiMZL(EMZL)erdanliezuoweidulidejibingshitileixing(PCMZL)。(4)ertonglinbajiebianyuanqulinbaliu(pNMZL)shicongNMZLxiadeyigeyaxingshengjichengweiyigedulidejibingshitileixing。lvpaoxinglinbaliuFollicular lymphomayuanweilvpaoxingBxibaozhongliu(ISFN)?In situ follicular B-cell neoplasmyuanweilvpaoxingzhongliu(yuanweilvpaoxingliubian)lvpaoxinglinbaliu(FL)?Follicular lymphomaxiangtongertongxinglvpaoxinglinbaliu?Paediatric-type follicular lymphomaxiangtongshierzhichangxinglvpaoxinglinbaliu?Duodenal-type follicular lymphomaxiangtongpifulvpaozhongxinlinbaliuCutaneous follicle centre lymphomayuanfaxingpifulvpaozhongxinlinbaliu?Primary cutaneous follicle centre lymphomaxiangtongtaoxibaolinbaliuMantle cell lymphomayuanweitaoxibaozhongliu(ISMCN)?In situ mantle cell neoplasmyuanweitaoxibaoliubiantaoxibaolinbaliu(MCL)?Mantle cell lymphomaxiangtongbaixuebingxingfeilinbajiexingtaoxibaolinbaliu(Leukemic non-nodal mantle cell lymphoma,feilinbajieMCL,nnMCL)?xiangtong【zhu】feilinbajieMCL(nnMCL)yuMCLxiangbi,daduomeiyouzhengzhuang,qiyuhouxiangduigenghao,zhuyaoshixueye、gusuihepizangshoulei,henshaohuozhemeiyoulinbajiezhongda。duoxingBxibaolinbaliuzhuanhuaTransformations of indolent B-cell lymphomaduoxingBxibaolinbaliuzhuanhua?Transformations of indolent B-cell lymphomawu【zhu】shoucibaduoxingBxibaolinbaliudegaojibiezhuanhuazuoweiyigedulibufendanlie。daBxibaolinbaliuLarge B-cell lymphomas(LBCL)mimandaBxibaolinbaliu,feitezhixing(NOS)?Diffuse large B-cell lymphoma(DLBCL),NOSxiangtongfuhanTxibao/zuzhixibaodedaBxibaolinbaliu?T-cell/histiocyte-rich large B-cell lymphomaxiangtongmimandaBxibaolinbaliu/gaojibieBxibaolinbaliu,ban MYC he BCL2 zhongpai?DLBCL/HGBL with MYC and BCL2 rearrangementsgaojibieBxibaolinbaliu,ban MYC he BCL2 he/huo BCL6 zhongpaiALKyangxingdaBxibaolinbaliu?ALK-positive large B-cell lymphomaxiangtongdaBxibaolinbaliu,ban IRF4 zhongpai?Lagre B-cell lymphoma with IRF4 rearrangementxiangtonggaojibieBxibaolinbaliu,ban 11q yichang?HGBL with 11q aberrationsBurkittyanglinbaliu,ban 11q yichanglinbaliuyangrouyazhongbing?Lymphomatoid granulomatosisxiangtongEBVyangxingmimandaBxibaolinbaliu?EBV-positive diffuse large B-cell lymphomaEBVyangxingmimandaBxibaolinbaliu,feitezhixing(NOS)mimandaBxibaolinbaliu,banmanxingyanzheng(yumanxingyanzhengxiangguandemimandaBxibaolinbaliu)?Diffuse large B-cell lymphoma associated with chronic inflammationxiangtongxianweidanbai(xianweisu)xiangguandaBxibaolinbaliu?Fibrin-associated large B-cell lymphoma(disibanshiyumanxingyanzhengxiangguandemimandaBxibaolinbaliudeyigeyaxing)tiyeguozaixiangguandaBxibaolinbaliu?Fluid overload-associated large B-cell lymphomawujiangmuxibaolinbaliu?Plasmablastic lymphomaxiangtongyuanfaxingmianyihuomianbuwei(tequanbuwei)daBxibaolinbaliu?Primary large B-cell lymphoma of immune-privileged sites(disibanweidandufenxing,baokuodi4banzhongdeyuanfazhongshushenjingxitong,yuanfaboliti、shiwangmo、zuowandengbuweidemimandaBxibaolinbaliu)yuanfapifumimandaBxibaolinbaliu,tuixing?Primary cutaneous diffuse large B-cell lymphoma,leg typexiangtongxueguanneidaBxibaolinbaliu?Intravascular large B-cell lymphomaxiangtongyuanfazonggedaBxibaolinbaliu?Primary mediastinal large B-cell lymphomaxiangtongzonggehuiqulinbaliu(MGZL)?Mediastinal grey zone lymphomaBxibaolinbaliu,wufafenlei,tezhengjieyuDLBCLhejingdianhuoqijinlinbaliuzhijiangaojibieBxibaolinbaliu,feitezhixing?High-grade B-cell lymphoma(HGBL),NOSxiangtong【zhu】daBxibaolinbaliubaokuoDLBCLfeitezhixingheqita17getedingdaBxibaolinbaliu。(1)DLBCL,NOS?shizuichangjiandeleixing,shiyizuyizhixingdelinbaliu,qixingtai、biaoxingdengjunbumanzumouzhongtedingdaBxibaolinbaliudezhenduanbiaozhun。disibandingyideliangzhongzhuyaoyaxingrengshiyong,jixuqufenGCB/ABC(GCB/feiGCB)yaxing。(2)tiyeguozaixiangguandaBxibaolinbaliu?yeshixinyinrudeleixing,zhuyaobiaoxianweitiqiangshoulei,zuichangjianshixiongmoqiangshoulei,changyoudaozhiyetiguozaidejichujibing(manxingxinshuai、shenshuaijie、ganshuaijie/ganyinghuadeng),duojianyulaonianren,yuhouxiangduijiaohao。yaozhuyi,tayuyuanfaxingshenchuxinglinbaliu(PEL)jiyinbiaodapuheyuhoujunbutong,PELyuhougengcha。PELmuqianguiruKSHV/HHV8xiangguanBxibaolinbazengzhixingjibinghelinbaliuzheyijiazu/zhongleizhong。(3)mianyihuomianbuweideyuanfadaBxibaolinbaliu?yexinbanfenleiyinrudeyigexindezongcheng,shifashengyumianyigongnengzhengchangrenqundeyizuyuanfaqinxixingBxibaolinbaliu,yuanfabuweibaokuozhongshushenjingxitong、bolitishiwangmo、zuowan:yuanfaxingzhongshushenjingxitongDLBCL、yuanfaxingzuowanLBCL、yuanfaxingbolitishiwangmoLBCL。jianglaikenenghuanhuikuochong(biruruxian、pifudeng)。(4)zonggehuiqulinbaliu(MGZL)?juyouyuanfazonggeBxibaolinbaliu(PMBL)hejingdianxinghuoqijinlinbaliu(cHL)dezhongdietezheng,jinfashengyuzongge,shuyudanyishengwuxuetezhengdejibingshiti。BurkittlinbaliuBurkitt lymphomaBurkittlinbaliu(bojitelinbaliu)?Burkitt lymphoma(BL)xiangtong【zhu】bojitelinbaliujiwanggenjuliuxingbingxuebeijinghediliweizhifenweisanzhongliuxingbingxueyaxing:difangxingBL、feidifangxing/sanfaxingBL、mianyiquexianxiangguanBL。kaolvdaoEBVganranzaizaoqifabingjizhizhongqizhongyaozuoyong,jiyufenzitezhengqufenweiliangzhongyaxingqudailiuxingbingxueyaxing,ji:EBVyangxingBLheEBVyinxingBL。KSHV/HHV8xiangguanBxibaolinbazengzhixingjibinghelinbaliuKSHV/HHV8-associated B-cell lymphoid proliferations and lymphomasyuanfaxingshenchuxinglinbaliu(PEL)?Primary effusion lymphomaxiangtongKSHV/HHV8yangxingmimandaBxibaolinbaliu?KSHV/HHV8-positive diffuse large B-cell lymphomaHHV8yangxingmimandaBxibaolinbaliu,feitezhixingKSHV/HHV8yangxingshishengfazhongxinlinbazengzhixingjibing?HSHV/HHV8-positive germinotropic lymphoproliferative disorderHHV8yangxingshishengfazhongxinlinbazengzhixingjibing【zhu】KSHV/HHV8(kaboxirouliuzuozhenbingdu/renleizuozhenbingdu8xing)ganranxiangguandelinbazengzhixingjibingbaokuo:KSHV/HHV8xiangguandeduozhongxinCastlemanbing(KSHV/HHV8-MCD,guidaoBxibaoweizhudezhongliuyangbingbianleibiexia)、yuanfaxingshenchuxinglinbaliu?(Primary effusion lymphoma,PEL)、qiangwaiPEL(EC-PEL)、KSHV/HHV8yangxingmimandaBxibaolinbaliu?(KSHV/HHV8-DLBCL)、KSHV/HHV8yangxingshishengfazhongxinlinbazengzhixingjibing?(KSHV/HHV8-GLPD)。yumianyiquexianheshidiaoxiangguandelinbazengzhihelinbaliuLymphoid proliferations and lymphomas associated with immune deficiency and dysregulationmianyiquexianxiangguanxingsabazuzhizengshengxingjibingmianyiquexian/shidiao(IDD)yinqideguoduzengsheng?Hyperplasias arising in immune deficiency/dysregulationweilieru,disibanbubaokuozainei,disibanbaokuofei(zuzhi)pohuaixingyizhihoulinbazengzhixingjibing(feipohuaixingPTLD)dengmianyiquexian/shidiaoyinqideduoxingxinglinbazengzhi(duoxingxinglinbazuzhizengzhixingjibing)?Polymorphic lymphoproliferative disorders arising in immune deficiency/dysregulationweilieru(disibanbubaokuozainei,baokuoduoxingxingyizhihoulinbazuzhizengzhixingjibing(duoxingxingPTLD)、qitayiyuanxingmianyiquexianxiangguandelinbazuzhizengshengxingjibingdeng)EBVyangxingpifuzhanmokuiyang?EBV-positive mucocutaneous ulcer(EBVMCU)xiangtongmianyiquexian/shidiaoyinqidelinbaliu?Lymphoma arising in immune deficiency/dysregulationweilieru,disibanbubaokuozaineidisibanbaokuodanxingxingyizhihoulinbazuzhizengzhixingjibing(danxingxingPTLD)、jingdianxinghuoqijinlinbaliuyangyizhihoulinbazuzhizengzhixingjibing、HIVganranxiangguanlinbaliudeng)mianyixiangguanlinbayangzengshenghelinbaliudexiantianxingcuowu(xiantianxingmianyiquexianxiangguanlinbazengzhihelinbaliu,mianyichushengcuowuxiangguandelinbazengzhihelinbaliu)?Inborn error of immunity-associated lymphoid proliferations and lymphomaslinbazengzhixingjibingxiangguan,banyuanfamianyijibing(yuyuanfaxingmianyijibing/quexianxiangguandelinbazengzhixingjibing)【zhu】mianyiquexian/shidiao,mianyiquexianbing(immunodeficiency diseases,IDD)shiyizuyouyumianyixitongfayubuquanhuozaoshousunhaisuozhidemianyigongnengquexianyinqidejibing,youerzhongleixing:①yuanfaxingmianyiquexianbing(xiantianxingmianyiquexianbing),yuyichuanyouguan,duofashengzaiyingyouer。②jifaxingmianyiquexianbing(huodexingmianyiquexianbing),kefashengzairenhenianling,duoyinyanzhongganranyouqishizhijieqinfanmianyixitongdeganran、exingzhongliu、yingyongmianyiyizhiji、fangliaohualiaodengyuanyinyinqi。yupeixitubianxiangguandeyuanfaxingmianyiquexianbeiguojimianyixuehuilianhehuizhongxinmingmingwei“mianyichushengcuowu”(inborn error of immunity,IEI)(jiwangchengweixiantianxingmianyiquexian),xinbanWHO-HAEM5fenleicaiyonggaishuyumingcheng。huoqijinlinbaliuHodgkin lymphmajingdianxinghuoqijinlinbaliu?Classic Hodgkin lymphma(cHL)xiangtongjiejiexinglinbaxibaoweizhuxinghuoqijinlinbaliu?Nodular lymphocyte predominant Hodgkin lymphma(NLPHL)xiangtong【zhu】huoqijinlinbaliuzaijiubanzhongzuoweidulideleibie(category),Hodgkinxibao(RSxibaodedanhebianyixing)heReed-Sternbergxibao(lisixibao,RSxibao,biaoxianweiduohejuxibao)qiyuanyushengfazhongxindeBxibao,bingkaolvdaodangdaidezhiliaomoshi,bahuoqijinlinbaliudandufenchulaideyuhouyiyibuda,yincixinbanfenleibahuoqijinlinbaliubeiguidaochengshuBxibaozhongliuleibie(category)xia,zuoweichengshuBxibaozhongliudeyigejiazu/zhonglei(family/class)。linbaxibaoweizhuxinghuoqijinlinbaliu(LPHL),zhanhuoqijinlinbaliu5%-6%,dabufenzaidibeijingxiakejiandaojiejieyangjiegou,beijingweixiaolinbaxibaojujimijichengjiejiefenbu,xiangsiyulvpaolinbaliu,yechengweijiejiexinglinbaxibaoweizhuxingHL(NLPHL)。jinyoujishaoshuzhenduanxingdeRSxibao,qiechangweiyileichengwei“L&H”RSxibao,yechengweiHLdexibaoxibaohe/huozuzhixibaoyaxing,yechengwei“baomihuaxibao”。kefashengzairenhenianling,zhongweifabingnianling60sui,nanxingduojian,changqinfanlinbajie,yuhoujiaohao。mianyizuhuaranseCD30(-),biaodaBxibaokangyuan(CD20+,CD15-)。kehouqifufa,kezhuanhuaweiBxibaoNHL。jingdianxinghuoqijinlinbaliu(CHL),juyouxingtaixuedianxingdezhenduanxingRSxibaojiqidanhebianyixing(huoqijinxibao),liuxibaotezhengxingbiaodaCD30+,changbiaodaCD15+,CE20-。baokuosigeyaxing:jiejieyinghuaxingcHL(NSCHL)、fuyulinbaxibaoxingcHL(LRCHL)、hunhexibaoxingcHL(MCHL)、linbaxibaoxiaojianxingcHL(LDCHL)。jiangxibaozhongliujiqitajuyoufudanbaidejibing(12geshiti/leixing)Plasma cell neoplasms and other diseases with paraproteinsdiwubanfenleidisiban(xiuding)fenleidankelongbingzhongqiudanbaibingMonoclonal gammopathieslengningjisubing(CAD)?Cold agglutinin diseasewuyiyiweimingdeIgMdankelongbingzhongqiudanbaibing?IgM monoclonal gammopathy of undetermined significance(IgM MGUS)xiangtongyiyiweimingdefeiIgMdankelongbingzhongqiudanbaibing?Non-IgM MGUSxiangtongjuyoushenzangyiyidedankelongbingzhongqiudanbaibing?Monoclonal gammopathy of renal significance(MGRS)weilie rudankelongmianyiqiudanbaichenjidejibingDiseases with monoclonal immunoglobulin depositionmianyiqiudanbaixiangguan(AL)dianfenyangbianxing?Immunoglobulin-related(AL) amyloidosisyuanfaxing(qinglian)dianfenyangbianxingdankelongmianyiqiudanbaichenjibing?Monoclonal immunoglobulin deposition diseaseqinglianhezhonglianchenjibingzhonglianbingHeavy chain diseases(HCD)μ(Mu)zhonglianbing?Mu heavy chain diseasexiangtongγ(Gamma)zhonglianbing?Gamma heavy chain diseasexiangtongα(Alpha)zhonglianbing?Alpha heavy chain diseasexiangtongjiangxibaozhongliuPlasma cell neoplasmsjiangxibaoliu?Plasmacytomaxiangtongjiangxibaogusuiliu?Plasma cell myeloma/multiple myelomaxiangtongfuzhongliuzonghezhengxiangguandejiangxibaozhongliu?Plasma cell neoplasms with associated paraneoplastic syndromePOEMS zonghezhengTEMPI zonghezhengAESOP zonghezheng(adenopathy and extensive skin patch overlying a plasmacytoma,linbajiezhongdaheguangfanpifubankuaibanjiangxibaoliu)xiangtong(danAESOP zonghezhengyiqianbubaokuozainei)TheNKxibaolinbazengzhixingjibinghezhongliuT-cell and NK-cell lymphoid proliferations and lymphomas(39geshiti/leixing)Txibaoweizhuzhongliuyangbingbian(3geshiti/leixing)Tumor-like lesions with T-cell predominancediwubanfenleidisiban(xiuding)fenleijuchi-tengbenbing?Kikuchi-Fujimoto disease(KFD)wuduoxing T linbamuxibaoxingzengzhi?Indolent T-lymphoblastic proliferation(ITLP)wuzishenmianyixinglinbazengzhizonghezheng?Autoimmune lymphoproliferative syndrome(ALPS)wu【zhu】Txibaoweizhuzhongliuyangbingbianxidiwubanxinyinrudefenlei。qiantiTxibaozhongliu(2geshiti/leixing)Precursor T-cell neoplasmsji:yuanshiTlinbaxibaobaixuebing/linbaliu(Tlinbaxibaobaixuebing/linbaliu,Tlinbamuxibaobaixuebing/linbaliu,T-lymphoblastic leukaemias/lymphomas,T-ALL/LBL)diwubanfenleidisiban(xiuding)fenleiTlinbamuxibaobaixuebing/linbaliu,feitezhixing?T-lymphoblastic leukaemia/lymphoma,NOS(T-ALL/LBL,NOS)Tlinbamuxibaobaixuebing/linbaliuzaoqiTqiantilinbamuxibaobaixuebing/linbaliu?Early T-precursor ALL/LBL (ETP-ALL/LBL)zaoqiTqiantilinbaxibaobaixuebing(yishanchu)NKlinbamuxibaobaixuebing/linbaliu(yuanshiNKxibaobaixuebing/linbaliu)【zhu】NKlinbamuxibaobaixuebing/linbaliuzaidisibanfenleizhongzuoweilinshijibingleixing,youyuquefamingquedekekaodezhenduanbiaozhunyijixiangguandexingtaixuehemianyibiaoxingtezheng,diwubanfenleizhongweidanduliechu。chengshuTxibaoheNKxibaozhongliu(9gejiazu/zhonglei,34geshiti/leixing)Mature T-cell and NK-cell neoplasms(1)chengshuTxibaoheNKxibaobaixuebing(6ge);(2)yuanfaxingpifuTxibaolinbaliu(9ge);(3)changdaoTxibaoheNKxibaolinbazengzhihelinbaliu(5ge);(4)ganpiTxibaolinbaliu(1ge);(5)jianbianxingdaxibaolinbaliu(3ge);(6)linbajieTlvpaofuzhuxibaolinbaliu(3ge);(7)qitawaizhouTxibaolinbaliu(1ge);(8)EBVyangxingNK/Txibaolinbaliu(2ge);(9)ertongEBVyangxingTxibaoheNKxibaolinbazengzhihelinbaliu(4ge)【zhu】chengshuTxibaoheNKxibaozhongliugenjuxibaoqiyuan/fenhuazhuangtai、linchuangtezheng、jibingbuwei/weizhi、xibaoxingtaixuedengqufenwei9gejiazu/zhonglei,gong34gejibingshiti/leixing。daduoshuTxibao、NKxibaozhongliukeguirugezixiangyingdeTxibao、NKxibaopuxi,danyoudejibingleixingbaokuoNKxibao、Txibao、hunhehuobuquedingdezhongliubiaoxing,TxibaoheNkxibaoqiyuandequfennanyuquedinghuobuqingchu,yincidiwubanfenleizhongmeiyoujiandandifenweiTxibaozhongliuheNKxibaolianglei,biruchengshuTxibaoheNKxibaobaixuebing、EBV-yangxingjiexingTxibaoheNKxibaolinbaliu、jiewaiNK/Txibaolinbaliudeng。diwubanfenleidisiban(xiuding)fenleichengshuTxibaoheNKxibaobaixuebingMature T-cell and NK-cell leukaemiasT-youlinbaxibaobaixuebing(T-PLL)?T-prolymphocytic leukaemiaxiangtongTdakelilinbaxibaobaixuebing(T-LGLL)?T-large granular lymphocytic leukaemiaTxibao(dakeli)linbaxibaobaixuebingNKdakelilinbaxibaobaixuebing(NK-LGLL)?NK-large granular lymphocytic leukaemiaNKxibaomanxinglinbazengshengxingjibingchengren T xibaobaixuebing/linbaliu(ATLL)?Adult T-cell leukaemia/lymphomaxiangtongSezaryzonghezheng(saizhalizonghezheng,SS)?Sézary syndromexiangtongqinxixing NK xibaobaixuebing(ANKL)?Aggressive NK-cell leukaemiaxiangtongyuanfaxingpifuTxibaolinbaliuPrimary cutaneous T-cell lymphomasyuanfaxingpifu CD4 yangxingxiao /zhongT xibaolinbazengzhixingjibing?Primary cutaneous CD4-positive small or medium T-cell lymphoproliferative disorderxiangtongyuanfaxingpifuzhiduan CD8 yangxinglinbazengzhixingjibing?Primary cutaneous acral CD8-positive lymphoproliferative disorderyuanfaxingpifuzhiduan CD8 yangxing T xibaolinbaliuzuoyangrouyazhong?Mycosis fungoides(MF)xiangtongyuanfaxingpifuCD30yangxingTxibaolinbazengzhixingjibing:linbaliuyangqiuzhenbing?Primary cutaneous CD30-positive T-cell LPD:Lymphomatoid papulosisxiangtongyuanfaxingpifuCD30yangxingTxibaolinbazengzhixingjibing:yuanfaxingpifujianbianxingdaxibaolinbaliu?Primary cutaneous CD30-positive T-cell LPD:Primary cutaneous ALCLxiangtongpixiazhimoyanyangTxibaolinbaliu?Subcutaneous panniculitis-like T-cell lymphomaxiangtongyuanfaxingpifu γ/δ T xibaolinbaliu?Primary cutaneous gamma/delta T-cell lymphomaxiangtongyuanfaxingpifuCD8yangxingqinxixingshibiaopixibaoduxingTxibaolinbaliu?Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphomaxiangtongyuanfaxingpifuwaizhouTxibaolinbaliu,feitezhixing(NOS)?Primary cutaneous peripheral T-cell LPD,NOSwu【zhu】yuanfaxingpifuTxibaolinbaliu(CTCL)shixinbanfenleizhongchengshuT/NKxibaozhongliuleibiexiadeyigezhuanmendejiazu/zhonglei,baokuo9gejibingshiti/leixing。changdaoTxibaoheNKxibaolinbazengzhihelinbaliuIntestinal T-cell and NK-cell Lymphoid proliferations and lymphomasweichangdaoduoxingTxibaolinbaliu?Indolent T-cell lymphoma of the gastrointestinal tractweichangdaoduoxingTxibaolinbazengzhixingjibingweichangdaoduoxing NK xibaolinbazengzhixingjibing?Indolent NK-cell lymphoproliferative disorder of the gastrointestinal tractwuchangbingxiangguanTxibaolinbaliu?Enteropathy-associated T-cell lymphomaxiangtongdanxingxingshishangpixingchangdao T xibaolinbaliu?Monomorhpic epitheliotropic intestinal T-cell lymphomaxiangtongchang daoT xibaolinbaliu,feitezhixing(NOS)?Intestinal T-cell lymphoma ,NOSxiangtong【zhu】weichangdao(GI)duoxingTxibaolinbazengzhixingjibingxinmingmingweiweichangdaoduoxingTxibaolinbaliu,mingmingcong“linbazengzhixingjibing”dao“linbaliu”dezhuanbian,shijiyuqigaofashenglvhejibingdebosanxing,danlinchuangguochengrengranmanchang,suoyirengbaoliu“duoxing”zheyixiandingci。weichangdaoduoxingNKxibaolinbazengzhixingjibing(iNKLPD,indolent NK-cell lymphoproliferative disorder)shixinzengleixing,jiwangrenweishiyizhongfanyingxingguochengerchengweilinbaliuyangweibinghuoNKxibaochangbing,danzuijindefaxianzhichitadezhongliuxingtezheng,yincixinyinruzuoweiyigedulidejibingshiti/leixing。ganpiTxibaolinbaliuHepatosplenic T-cell lymphomaganpiTxibaolinbaliu(HSTCL)?Hepatosplenic T-cell lymphomaxiangtongjianbianxingdaxibaolinbaliuAnaplastic large cell lymphomaALK-yangxingjianbianxingdaxibaolinbaliu?ALK-positive anaplastic large cell lymphoma(ALK+ALCL)jianbianxingdaxibaolinbaliu, ALK-yangxingALK-yinxingjianbianxingdaxibaolinbaliu?ALK-negative anaplastic large cell lymphoma(ALK-ALCL)jianbianxingdaxibaolinbaliu, ALK-yinxingrufangzhiruwuxiangguanjianbianxingdaxibaolinbaliu?Breast implant-associated anaplastic large cell lymphoma(BIA-ALCL)xiangtong【zhu】jianzhibianxingdaxibaolinbaliu(ALCL)jiazubaokuo3gejibingshiti/leixing:ALK+ALCL、ALK-ALCL、BIA-ALCL。junweichengshuTxibaolinbaliu,CD30qiangbiaoda,tongchangbubiaodaTxibiaozhiwu。yuanfaxingpifuALCLmeiyouguizaigaijiazuxia,ershiguileidaolingyijiazu“yuanfaxingpifuTxibaolinbazengzhihelinbaliu”xia,qiyuquanshenxingALK-ALCLxiangbiyuhougengjia。rufangzhiruwuxiangguandeALCLshiyizhongbutongyuqitaALK-ALCLdejibingleixing,shiyizhongfeiqinruxingzhongliu,yucucaobiaomianrufangzhiruwuxiangguan,linchuangyuhouxiangduijiaohao,danruguoqinfanlinjinjiegouzeyuhoubiancha。linbajieTlvpaofuzhu(TFH)xibaolinbaliuNodal T-follicular helper(TFH) cell lymphomalinbajieTFHxibaolinbaliu,xueguanmianyimuxibaoxing?Nodal TFH cell lymphoma ,angioimmunoblastic-type(nTFHL-AI)xueguanmianyimuxibaoxingTxibaolinbaliu(AITL)linbajieTFHxibaolinbaliu,lvpaoxing?Nodal TFH cell lymphoma ,follicular-type(nTFHL-F)lvpaoxingTxibaolinbaliulinbajieTFHxibaolinbaliu,feitezhixing?Nodal TFH cell lymphoma ,NOS(nTFHL-NOS)juyouTFHbiaoxingdejiexingwaizhouTxibaolinbaliu【zhu】linbajielvpaofuzhuxingTxibaolinbaliu(nTFHL)jiazubaokuo3gejibingshiti/leixing,junxilinbajieTxibaolinbaliu,juyouTFH(lvpaofuzhuxingTxibao)debiaoxinghejiyinbiaodatezheng。nTFHL-AI,angioimmunoblastic-type duiyingyuyiqiande“xueguanmianyimuxibaoxingTxibaolinbaliu”nTFHL-F,ollicular-type duiyuyingyuyiqiande“lvpaoTxibaolinbaliu”nTFHL-NOS duiyingyuyiqiande“juyouTFHbiaoxingdewaizhouTxibaolinbaliu”qitawaizhouTxibaolinbaliuwaizhouTxibaolinbaliu,feitezhixing(NOS)?Peripheral T-cell lymphoma,not otherwise specified(NOS)xiangtong【zhu】PTCL-NOSshiyizuyizhixinghenqiangdejibing,shipaichuxingzhenduan,tebieyaojianbienTFHL。EBVyangxingNK/TxibaolinbaliuEBV-positive NK/T-cell lymphomasEBVyangxingjiexingTxibaoheNKxibaolinbaliu?EBV-positive nodal T- and NK-cell lymphomawujiewaiNK/Txibaolinbaliu(ENKTL)?Extranodal NK/T-cell lymphomajiewaiNK/Txibaolinbaliu,bixing【zhu】jiewaiNK/Txibaolinbaliu(ENKTL)kefashengzaibutongdejiewaibuwei,yincishanchujiubanzhongdexiandingci“bixing”。EBVyangxingjiexingTxibaoheNKxibaolinbaliujiwangbeiguiruPTCL-NOSxiadeyigeyaxing,zaixinbanfenleizhongzuoweiyigedulidejibingshiti/leixing,zhuyaofashengzaidongyarenzhong,yuhoucha。ertongEBVyangxingTxibaoheNKxibaolinbazengzhihelinbaliuEBV-positive T- and NK-cell lymphoid proliferations and lymphomas of childhoodyanzhongwenchongdingyaoguomin?Severe mosquito bite allergyxiangtongzhongdouyangshuizuobinglinbazengzhixingjibing?Hydroa vacciniforme LPD(HVLPD)zhongdouyangshuizuobingyang(Hydroa vacciniforme-like)linbazengzhixingjibingxitongxingmanxinghuodongxingEBVjibing(xitongxingCAEBVD)?Systemic chronic active EBV diseaseTxibaoheNKxibaoleixingdemanxinghuodongxingEBVganran,xitongxingertongxitongxingEBVyangxingTxibaolinbaliu?Systemic EBV-positive T-cell lymphoma of childhoodxiangtong【zhu】(1)manxinghuodongxingEBVbing(CAEBVD):baokuojuzaozhengzhuanghe/huoduoxingxingshideyanzhongwenchongdingyaoguomin?heHVLPDjingdianxing?,yijiquanshenxingjibingHVLPDquanshenxing?hexitongxingCAEBVD?。(2)ertongxitongxingEBVyangxingTxibaolinbaliu?Hydroa vacciniforme(zhongdouyangshuizuobing,douchuangyangshuizuobing)linbazuzhidejianzhiyuanxingzhongliuStroma-derived neoplasms of lymphoid tissues(7geshiti/leixing)diwubanfenleidisiban(xiuding)fenleijianzhishutuxibaozhongliuMesenchymal dendritic cell neoplasmslvpaoshutuxibaorouliu?Follicualr dendritic cell sarcomaxiangtongEBV-yangxingyanxinglvpaoshutuxibaorouliu?EBV-positive inflammatory follicular dendritic cell sarcomayanxingjialiuyanglvpao/chengxianweixibaoshutuxibaorouliuxianweimuxibaowangzhuangxibaoliu?Fibroblastic reticular cell tumorxiangtongjixianweimuxibaoliuMyofibroblastic tumourjieneizhalanzhuangjixianweimuxibaoliu?Intranodal palisaded myofibroblastomawupiteyixingxueguanjianzhizhongliuSpleen-specific vascular-stromal tumourspixueguanjianzhiliuSplenic vascular-stromal tumourspizuoanxibaoxueguanliu?Littoral cell angiomawupicuogouliu?Splenic hamartomawupiyinghuaxingxueguanliuyangjiejiexingzhuanhua?Sclerosing angiomatoid nodular transformation of spleenwu【zhu】1、linbazuzhijianzhiyuanxingzhongliudemouxieleixingshilinbajiehuopizangsuoteyoude,guirubenfenleitixizhong。feilinbajiehepizangteyixingderuanzuzhizhongliu(biruxueguanliu、xueguanrouliu、linbaguanjiliu、kaboxirouliudeng)guidao2020niandiwubanWHOguheruanzuzhizhongliufenleizhong。2、linbazuzhijianzhi(jizhi)laiyuanzhongliushidiwubanxinyinrudefenlei,gaileibiexiabaokuosandalei:(1)jianzhishutuxibaozhongliu:cong“zuzhixibaoheshutuxibaozhongliu”leibiezhongyiguolaidelvpaoshutuxibaozhongliu(?he?)hechengxianweiwangzhuangxibaozhongliu?guiruzheyixinleibiemingxia(yinweilvpaoshutuxibaobingfeiyuanzizaoxueganxibao,ershijianzhilaiyuan)。lingwai,EBVyangxingyanxinglvpaoshutuxibaorouliu?youyujuyoudutedelinchuangbinglitezheng,conglvpaoshutuxibaorouliu?zhongdanliechulaizuoweidulidejibingleixing。(2)jixianweimuxibaoliu,xilinbajieteyixingjianzhizhongliu(linbajieneizhalanzhuangjixianweimuxibaoliu?)。(3)piteyixingjianzhizhongliu,baokuo:pizuoanxibaoxueguanliu?、picuogouliu?、piyinghuaxingxueguanliuyangjiejiexingzhuanhua?)。shutuxibaohezuzhixibaozhongliuDendritic cell and histiocytic neoplasms(11geshiti/leixing)diwubandisiban(xiuding)fenleijiangxibaoyangshutuxibaozhongliuPlasmacytoid dendritic cell neoplasmsyusuixizhongliuxiangguandechengshujiangxibaoyangshutuxibaozengzhiMature plasmacytoid dendritic cell proliferation associated with myeloid neoplasmwumuxibaoxingjiangxibaoyangshutuxibaozhongliuBlastic plasmacytoid dendritic cell neoplasmwulanggehansixibaoheqitashutuxibaozhongliuLangerhans cell and other dendritic cell neoplasmslanggehansixibaozhongliuLangerhans cells neoplasmslanggehansixibaozuzhixibaozengshengzhengLangerhans cell histiocytosisxiangtonglanggehansixibaorouliuLangerhans cell sarcomaxiangtongqitashutuxibaozhongliuOther dendritic cell neoplasmsweidingleishutuxibaoliuIndeterminate dendritic cell tumourxiangtong(weiquedingshutuxibaozhongliu)zhituzhuangshutuxibaorouliuInterdigitating dendritic cell sarcomaxiangtong(jiaozhishutuxibaorouliu)zuzhixibaozhongliuHistiocytic neoplasmsyounianhuangserouyazhongJuvenile xanthogranulomaxiangtong(bosanxingyounianhuangserouyazhong)Erdheim-Chesterbing(ECD)Erdheim-Chester diseasexiangtongRosai-Dorfmanbing(RDD)Rosai-Dorfman diseasewuALKyangxingzuzhixibaozengshengzhengALK-positive histiocytosiswuzuzhixibaorouliuHistiocytic sarcomaxiangtong【zhu】zuzhixibao/shutuxibaozhongliuzaixinbanfenleitixizhongdingweiyusuixizhongliuzhihou,tongchangrenweitamenqiyuanyuchangjiandesuixizuxibao(suixizuxibaochanshengdanhexibao/zuzhixibao/shutuxibaopuxi)。disibanzuzhixibao/shutuxibaozhongliuxiade“lvpaoshutuxibaorouliu”、“chengxianwei(xianweimuxibao)wangzhuangxibaozhongliu”,kaolvdaoshiyoulinbajizhixibaochanshengdezhongliu,diwubanfenleijiangqicongzuzhixibao/shutuxibaozhongliuzhongfenchulaiguirudaolinxizhongliu“linbazuzhijianzhiyuanxingzhongliu”xia。cankaowenxian:(1)The 5th edition of the World Health Organization Classifification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms. Leukemia(2022) 36:1703-1719.https://doi.org/10.1038/s41375-022-01613-1.(2)The 5th edition of the World Health Organization Classifification of Haematolymphoid Tumours: Lymphoid Neoplasms. Leukemia(2022) 36:1720-1748.https://doi.org/10.1038/s41375-022-01620-2.
如(搁耻)果(骋耻辞)是(厂丑颈)小(齿颈补辞)编(叠颈补苍)的(顿别)话(贬耻补)可(碍别)能(狈别苍驳)会(贬耻颈)起(蚕颈)身(厂丑别苍)离(尝颈)他(罢补)们(惭别苍)远(驰耻补苍)一(驰颈)点(顿颈补苍)吧(叠补)。
王力宏台北演唱会情绪激动,连用12个排比句怒吐委屈,下跪谢粉丝首发2024-01-21 19:05·开心火龙果王力宏台北演唱会情绪激动,连用12个排比句怒吐委屈,下跪谢粉丝2024年,王力宏回到故乡台北,在一场引人瞩目的演唱会上,情绪激动地表达了自己的内心委屈。这一幕不仅让现场观众感同身受,也引发了更广泛的思考。演唱会开始时,王力宏带着满满的激情登上舞台,与他多年的粉丝们见面。他开始了他的音乐之旅,歌声淋漓尽致地传达着他的情感和才华。然而,每当王力宏唱到那些深情而充满回忆的歌曲时,他的情绪变得异常激动。在一首《爱你等于爱自己》中,王力宏的声音伴随着柔美的旋律,如同一把钥匙打开了观众心灵深处的情感之门。他用12个排比句怒吐委屈,表达了自己对于生活中的困惑和不公平的感慨。他唱道:“我以为我能够拥有一切,却发现自己什么都没有;我以为我可以改变一切,却发现自己无法改变任何事情;我以为我可以获得幸福,却发现自己只是在追逐虚幻的影子。”每一个字词都如同利刃般刺痛了观众的内心。观众们感同身受,他们深陷于王力宏的歌声之中,仿佛每一个字句都是他们自己的呼喊。在这个瞬间,房间里弥漫着一股共鸣的气息,人们不禁开始反思自己的生活。他们开始想象自己是否也曾经历过类似的困惑,是否也曾明明付出了努力却收获甚少。随着音乐的推进,王力宏的情绪逐渐达到高潮。他突然跪倒在舞台上,向观众表达了最真挚的感谢和敬意。他说:“谢谢你们,因为有你们,我才能够坚持走到今天;谢谢你们,因为有你们,我才能够成为自己。”他的声音带着一丝颤抖,让人不禁为他的坚持和执着而动容。观众们也被他的表演所感染,纷纷起立鼓掌。他们意识到,每个人都有自己的困境和委屈,但只有坚持和努力,才能够超越自己的枷锁,追逐心中的梦想。这次演唱会不仅仅是一场音乐盛宴,更是一次情感的释放和思考的启示。观众们在王力宏的表演中找到了共鸣,也发现了自己生活中类似问题的解决之道。回到家后,观众们开始思考自己的生活。他们明白,每个人都会遭遇不公平和委屈,但重要的是如何面对这些困难,并勇敢地迎接挑战。他们开始反思自己是否已经尽力去追求自己的梦想,是否有时放弃过轻易放弃的事物。他们决定要坚持下去,不再被生活中的困境击垮,而是积极寻找解决问题的方法。与此同时,更多的人受到王力宏演唱会的影响,他们开始关注自己内心深处的感受,思考自己的生活是否与内心的渴望相符。王力宏的音乐成为了他们勇敢面对人生挑战的动力和支持。在那个特别的夜晚,王力宏台北演唱会不仅仅是一场音乐盛宴,更是观众们反思、启发和成长的契机。他的情绪激动、怒吐委屈以及下跪谢粉丝,让人们感同身受,并引发了他们对自己生活中类似问题的深思。正如王力宏所唱的那样:“我们都是追逐梦想的人,让我们一起坚持,追寻属于自己的幸福。”刘罗锅的故事已经在第一部讲完,再拍没有任何意义。和平精英可以看到胸吗 - 电玩兔
文|记者 符畅 通讯员 李妍静图|通讯员提供