91ÊÓƵרÇø

danshiruguojiaocaixiejiaotanajiufeichangheshiliao¡£2024-06-04 14:19¡¤chezuoju

½ü(´³¾±²Ô)ÈÕ(¸é¾±)£¬ÖÐ(´Ü³ó´Ç²Ô²µ)¹ú(³Ò³Ü´Ç)ס(´Ü³ó³Ü)·¿(¹ó²¹²Ô²µ)ºÍ(±á±ð)³Ç(°ä³ó±ð²Ô²µ)Ïç(³Ý¾±²¹²Ô²µ)½¨(´³¾±²¹²Ô)Éè(³§³ó±ð)²¿(µþ³Ü)¡¢²Æ(°ä²¹¾±)Õþ(´Ü³ó±ð²Ô²µ)²¿(µþ³Ü)¡¢ÖÐ(´Ü³ó´Ç²Ô²µ)¹ú(³Ò³Ü´Ç)ÈË(¸é±ð²Ô)Ãñ(²Ñ¾±²Ô)Òø(³Û¾±²Ô)ÐÐ(³Ý¾±²Ô²µ)Áª(³¢¾±²¹²Ô)ºÏ(±á±ð)·¢(¹ó²¹)²¼(µþ³Ü)¡¶±¨(µþ²¹´Ç)¸æ(³Ò²¹´Ç)¡·£¬È«(²Ï³Ü²¹²Ô)Ãæ(²Ñ¾±²¹²Ô)Åû(±Ê¾±)¶(³¢³Ü)ÁË(³¢¾±²¹´Ç)2022Äê(±·¾±²¹²Ô)È«(²Ï³Ü²¹²Ô)¹ú(³Ò³Ü´Ç)ס(´Ü³ó³Ü)·¿(¹ó²¹²Ô²µ)¹«(³Ò´Ç²Ô²µ)»ý(´³¾±)½ð(´³¾±²Ô)ÔË(³Û³Ü²Ô)ÐÐ(³Ý¾±²Ô²µ)Çé(²Ï¾±²Ô²µ)¿ö(°­³Ü²¹²Ô²µ)¡£

dushengnvdewo£¬geiqushidefuqindongtuqianfen£¬meixiangdaorelailiaozhenzhenfeiyihezhiyilinbaliu | WHOdi5banlinbazuzhizhongliufenlei(zhongyingduizhaozuiquanzuishiyong)yuanchuang2023-07-05 20:58¡¤zhongliuzhuankeyisheng2022nianshijieweishengzuzhi£¨WHO£©fabudi5banzaoxueyulinbazuzhizhongliufenlei£¨WHO-HAEM5£©The 5th edition of the WHO Calssification of Haematolymphoid Tumorsyi¡¢suixizengzhihezhongliubaokuokelongxingzaoxue¡¢gusuizengzhixingzhongliu£¨manxingsuixibaobaixuebing¡¢manxingzhongxinglixibaobaixuebingdeng£©¡¢gusuizengshengyichangzhongliu£¨MDS£©¡¢jixingsuixibaixuebing£¨AML£©dengdeng£¬tongchangguishuxueyeneike¡£er¡¢shutuxibao/zuzhixibaozhongliushutuxibao/zuzhixibaozhongliuzaixinbanfenleitixizhongdingweiyusuixizhongliuzhihou£¬tongchangrenweitamenqiyuanxiangjin£¬qiyuanyuchangjiandesuixizuxibao£¨chanshengdanhexibao/zuzhixibao/shutuxibaopuxi£©£¬disibanfenleizhong¡°zuzhixibao/shutuxibaozhongliu¡±xiade¡°lvpaoshutuxibaorouliu¡±¡¢¡°xianweimuxibaowangzhuangxibaozhongliu¡±shiyoulinbajizhixibaochanshengdezhongliu£¬diwubanfenleijiangqifenchulaiguidao¡°linbazuzhijianzhiyuanxingzhongliu¡±xia¡£san¡¢Bxibaolinbazengzhixingjibinghezhongliusi¡¢TheNKxibaolinbazengzhixingjibinghezhongliuwu¡¢linbazuzhijianzhiyuanxingzhongliu£¨xinyinrufenlei£©shuyulinxizhongliu£¨linbazuzhizhongliu£©£¬benwenzhuyaoshejizhesanbufenneirong¡£liu¡¢yichuanzhongliuzonghezheng£¨xinyinruzhangjie£©yichuanzhongliuzonghezhengbaokuoyihuansuixizhongliuhelinxizhongliuxiangguandezonghezheng¡£yichuanxingzhongliuzonghezheng£¨yichuanyiganzonghezheng£©xixinyinrudefenlei£¬baokuofankenipinxue£¨Fanconipinxue£©¡¢bulumuzonghezheng£¨Bloomzonghezheng£¬mianbuhongbanzuoruzonghezheng£©¡¢gongjishidiaomaoxixueguankuozhangzonghezheng£¨AT£©¡¢RASbing£¨RASzonghezheng£©¡¢Nijmegen-Breakagezonghezheng£¨Nijmegenduanliezonghezheng£¬Nijmegen breakage syndrome£¬NBS£©deng¡£yihuansuixizhongliudeyichuanxingzhongliuzonghezheng£ºFanconipinxue¡¢RASbingdeng£¬ATheNBSzeyulinxizhongliuyouweixiangguan£¬fenbieyuATMheNBNpeixitubianxiangguan¡£guanyudi5banfenleidejidianzhongyaoshuoming£º1¡¢jibingfencengmuluhejiegouzunzhaoguigejibiedizengdeshunxu£¬yimuliaoran£ºleibiecategory£¨biru£ºchengshuBxibaolinbaliu£©¡¢jiazu/zhongleifamily/class£¨biru£ºdaBxibaolinbaliu£©¡¢shiti/leixingentity/type£¨biru£ºmimanxingdaBxibaolinbaliu¡¢feitezhixing£©heyaxingsubtype£¨biru£ºmimanxingda B xibaolinbaliu£¬feitezhixing£¬shengfazhongxinBxibaoyang£©¡£2¡¢jibingfenleizunzhaoxibaopuxideshunxu£¨puxideguishuyijuliushixibaoshuhe/huomianyizuhuademianyibiaoxingfenxi£©£¬xianshiqiantixibaozhongliu£¬ranhoushichengshuexingzhongliu¡£zaiyigejiazu/zhonglei£¨family/class£©zhong£¬shiti/leixing£¨entity/type£©tongchangancongduoxingdaoqinxixingshunxupailie¡£3¡¢linbaliuyangjibing£¨yejiushiyulinbaliulinchuangtezhengxiangsidejibing£©yijixuyaojianbiedefeizhongliujibingshoucinarufenleizhong£¬youzhuyufangzhilinbaliuguoduzhenduanbingtigaoduilinchuangbinglixuebutongjibingleixingdeshibie¡£4¡¢yinrupeixizhongliuyiganzonghezhengzuoweizhuanmendedanjie£¬yitixianqiriyizengjiadelinchuangzhongyaoxing£¬zhexiezonghezhengtongchangyusuixihuolinxizhongliuxiangguan¡£5¡¢duixiantianxing£¨yuanfaxing£©mianyiquexianhehuodexing£¨jifaxing£©mianyijibingxiangguandelinbazengzhiyeyouxindefaxian£¬duizhexiegengxindeneirongyebaohanzaidiwubanxinfenleizhong¡£2022 niandiwuban WHO linbazuzhizhongliufenlei£ºzaoxueyulinbazuzhizhongliufenlei £¨WHO-HAEM5£©linxizhongliubufen£ºThe 5th edition of the WHO Calssification of Haematolymphoid Tumors-Lymphoid Neoplasmaslinbazuzhizhongliu£¨heji125geshiti/leixing£©yi¡¢Bxibaolinbazengzhixingjibinghezhongliu£¨3leibie£¬79geshiti/leixing£©1¡¢Bxibaoweizhudezhongliuyangbingbian£¨5ge£©2¡¢qiantiBxibaozhongliu£¨13ge£©3¡¢chengshuBxibaozhongliu£¨49ge£©4¡¢jiangxibaozhongliujiqitajuyoufudanbaidejibing£¨12ge£©er¡¢TheNKxibaolinbazengzhixingjibinghezhongliu£¨3leibie£¬39geshiti/leixing£©1¡¢Txibaoweizhudezhongliuyangbingbian£¨3ge£©2¡¢qiantiTxibaozhongliu£¨2ge£©3¡¢chengshuTheNKxibaozhongliu£¨34ge£©san¡¢linbazuzhijianzhiyuanxingzhongliu£¨7geshiti/leixing£©xiabiaozhongzuocebian2022niandiwubanWHO-HAEM5fenlei£¨linxi£©£¬youcewei2017niandisibanxiudingWHO-HAEM4Rfenlei£¨linxi£©¡£zhu£ºlymphoproliferative disorder£¨LPD£©£¬linba£¨zuzhi£©zengshengxingjibing£¬linba£¨zuzhi£©zengzhixingjibing¡£BxibaolinbazengzhixingjibinghezhongliuB-cell lymphoid proliferations and lymphomas£¨79geshiti/leixing£©Bxibaoweizhuzhongliuyangbingbian£¨5geshiti/leixing£©Tumor-like lesions with B-cell predominancediwubanfenleidisiban£¨xiuding£©fenleiyulinbaliuxiangsi£¨linbaliuyang£©fanyingxingfuhanBxibaodelinbaxibaozengzhijibing£¨fuhanBxibaodefanyingxinglinbayangzengsheng£¬kemonilinbaliu£©?Reactive B-cell rich lymphoid proliferations that can mimic lymphomawu£¨disibanweilieru£¬bubaokuozainei£¬xiatong£©IgG4xiangguanjibing?IgG4-related diseasewudanzhongxinCastlemanbing?Unicentric Castleman disease£¨UCD£©wutefaxingduozhongxinCastlemanbing£¨tefaxingMCD£©?Idiopathic multicentric Castleman diseasewuKSHV/HHV8 xiangguandeduozhongxinCastlemanbing£¨KSHV/HHV8xiangguandeMCD£©?KSHV/HHV8-associated multicenrtric Castleman diseaseduozhongxinCastlemanbing£¨MCD£©¡¾zhu¡¿Bxibaoweizhuzhongliuyangbingbianxidiwubanxinyinrudefenlei£¬baokuo5gebutongdejibingshiti/leixing£º£¨1£©yiBxibaoweizhudefeizhongliuxinglinbaxibaozengsheng£¨shejilinbajiehe/huojiewaibuwei£©£¬yulinbaliuxiangsi£¨linbaliuyang£©£¬yechengweifuhanBxibaodefanyingxinglinbayangzengsheng£¬kemonilinbaliu?¡£gaileijibingbaokuo£ºshengfazhongxindejinxingxingzhuanhua¡¢chuandan£¨chuanranxingdanhexibaozengduozheng£©¡¢nvxingshengzhidaodecaihuayangfanyingxinglinbazuzhizengsheng/linbaliuyangbingbian¡¢xitongxinghongbanlangchuang¡££¨2£©IgG4xiangguanjibing?£ºIgG4xiangguanlinbajiezhongdajuyouyuCastlemanbingxiangzhongdiedetezheng¡££¨3£©Castlemanbingbaokuosanzhongleixing£ºdanzhongxinCastlemanbing?¡¢tefaxingduozhongxinCastlemanbing?¡¢KSHV/HHV8 xiangguandeduozhongxinCastlemanbing?£¬tamendelinchuanghebinglixuetezhengbutong¡£qiantiBxibaozhongliu£¨13geshiti/leixing£©Precursor B-cell neoplasmsji£ºyuanshiBlinbaxibaobaixuebing/linbaliu£¨Blinbaxibaobaixuebing/linbaliu£¬Blinbamuxibaobaixuebing/linbaliu£¬B-cell lymphoblastic leukaemias/lymphomas£¬B-ALL/LBL£©£º£¨1£©Blinbamuxibaobaixuebing/linbaliu£¬feitezhixing£¨B-ALL/LBL£¬NOS£©£¨2£©bandingyiyichuanxueyichangdeBlinbaxibaobaixuebing/linbamuxibaolinbaliu£¨12ge£©diwubanfenleidisiban£¨xiuding£©fenleiBlinbaxibaobaixuebing/linbaliu£¬feitezhixing£¨B-ALL/LBL£¬NOS£©?B-cell lymphoblastic leukaemia/lymphoma£¬NOSxiangtongbandingyiyichuanxueyichangdeBlinbaxibaobaixuebing/linbamuxibaolinbaliu£¨12zhong£©Blinbaxibaobaixuebing/linbaliu£¨B-ALL/LBL£©£¬bangaochaoerbeiti?B-ALL/LBL with high hyperdiploidyBlinbaxibaobaixuebing/linbaliu£¨B-ALL/LBL£©£¬banchaoerbeitiBlinbaxibaobaixuebing/linbaliu£¨B-ALL/LBL£©£¬banyaerbeiti£¨dierbeiti£©?B-ALL/LBL with hypodiploidyxiangtongBlinbaxibaobaixuebing/linbaliu£¨B-ALL/LBL£©£¬baniAMP21?B-ALL/LBL with iAMP21xiangtongBlinbaxibaobaixuebing/linbaliu£¨B-ALL/LBL£©£¬ban BCR::ABL1 ronghe?B-ALL/LBL with BCR::ABL1 fusionBlinbaxibaobaixuebing/linbaliu£¨B-ALL/LBL£©bant(9;22)(q34;q11.2); BCR-ABL1rongheBlinbaxibaobaixuebing/linbaliu£¨B-ALL/LBL£©£¬ban BCR::ABL1 yangtezheng?B-ALL/LBL with BCR::ABL1-like featuresBlinbaxibaobaixuebing/linbaliu£¨B-ALL/LBL£©, banBCR-ABL1 yangBlinbaxibaobaixuebing/linbaliu£¨B-ALL/LBL£©£¬ban KMT2A zhongpai?B-ALL/LBL with KMT2A rearrangementBlinbaxibaobaixuebing/linbaliu£¨B-ALL/LBL£©£¬ban t(v;11q23.3); KMT2AzhongpaiBlinbaxibaobaixuebing/linbaliu£¨B-ALL/LBL£©£¬ban ETV6::RUNX1 ronghe?B-ALL/LBL with ETV6::RUNX1 fusionBlinbaxibaobaixuebing/linbaliu£¨B-ALL/LBL£©£¬ban t(12;21)(p13.2;q22.1); ETV6-RUNX1rongheBlinbaxibaobaixuebing/linbaliu£¨B-ALL/LBL£©£¬ban ETV6::RUNX1yangtezheng?B-ALL/LBL with ETV6::RUNX1-like featureswuBlinbaxibaobaixuebing/linbaliu£¨B-ALL/LBL£©£¬ban TCF3::PBX1 ronghe?B-ALL/LBL with TCF3::PBX1 fusionBlinbaxibaobaixuebing/linbaliu£¨B-ALL/LBL£©£¬ban t(1;19)(q23;p13.3); TCF3-PBX1rongheBlinbaxibaobaixuebing/linbaliu£¨B-ALL/LBL£©£¬ban IGH::IL3 ronghe?B-ALL/LBL with IGH::IL3 fusionBlinbaxibaobaixuebing/linbaliu£¨B-ALL/LBL£©£¬ban t(5;14)(q31.1;q32.1); IGH/IL3rongheBlinbaxibaobaixuebing/linbaliu£¨B-ALL/LBL£©£¬ban TCF3::HLF ronghe?B-ALL/LBL with TCF3::HLF fusionwuBlinbaxibaobaixuebing/linbaliu£¨B-ALL/LBL£©£¬banqitatedingyichuanxueyichang?B-ALL/LBL with other defined genetic abnormalitiesxiangtong¡¾zhu¡¿B-ALL/LBLfabingjizhizaidaduoshuqingkuangxiacunzaiyizhidequdongyinsu£¬baokuoiAMP21¡¢BCR::ABL1 ronghe¡¢ KMT2A zhongpai¡¢ETV6::RUNX1 ronghe¡¢TCF3::PBX1 ronghe¡¢ IGH::IL3 ronghe¡¢TCF3::HLF ronghedeng¡£genjuransetishumubianhua£¨chaoerbeiti¡¢yaerbeitideng£©¡¢ransetizhongpaihuocunzaiqitayichuanqudongyinsuerguiweibutongdeyaxing?-?¡£genjurenleijiyinzuzuzhijiyinmingmingweiyuanhuijianyi£¬caiyongshuangmaohao£¨::£©biaojironghejiyinxinmingcheng¡£chucizhiwaijibianjingguoquanmianjianceyerengranwufafenleideyileijibingzeguiweiBlinbaxibaobaixuebing/linbamuxibaolinbaliu£¬feitezhixing£¨B-ALL/LBL£¬NOS£©?chengshuBxibaozhongliu£¨12gejiazu/zhonglei£¬49geshiti/leixing£©Mature B-cell neoplasms£¨1£©zhongliuqianqihezhongliuxingxiaolinbaxibaozengzhi£¨2ge£©£¨2£©piBxibaolinbaliuhebaixuebing£¨4ge£©£¨3£©linbajiangxibaolinbaliu£¨1ge£©£¨4£©bianyuanqulinbaliu£¨4ge£©£¨5£©lvpaoxinglinbaliu£¨4ge£©£¨6£©pifulvpaozhongxinlinbaliu£¨1ge£©£¨7£©taoxibaolinbaliu£¨3ge£©£¨8£©duoxingBxibaolinbaliudezhuanhua£¨1ge£©£¨9£©daBxibaolinbaliu£¨18ge£©£¨10£©bojitelinbaliu£¨1ge£©£¨11£©KSHV/HHV8xiangguanBxibaolinbazengzhixingjibinghelinbaliu£¨3ge£©£¨12£©yumianyiquexianheshidiaoxiangguandelinbazengzhihelinbaliu£¨5ge£©£¨13£©huoqijinlinbaliu£¨2ge£©diwubanfenleidisiban£¨xiuding£©fenleizhongliuqianqihezhongliuxingxiaolinbaxibaozengzhiPre-neoplastic and neoplastic small lymphocytic proliferationsdankelong B linbaxibaozengduozheng£¨MBL£©?Monoclonal B-cell lymphocytosisxiangtongmanxinglinbaxibaobaixuebing/xiaolinbaxibaolinbaliu£¨CLL/SLL£©?Chronic lymphocytic leukaemia/small lymphocytic lymphomaxiangtongB-PLLbingmingbeishanchu£¨buzaishiweiyigejibingleixing£©Bxibaoyoulinbaxibaobaixuebing£¨B-PLL£©B-prolymphocytic leukemiapiBxibaolinbaliuhebaixuebingSplenic B-cell lymphomas and leukaemiasmaoxibaobaixuebing£¨HCL£©?Hairy cell leukaemiaxiangtongpibianyuanqulinbaliu£¨SMZL£©?Splenic marginal zone lymphomaxiangtongpimimanxinghongsuixiaoBxibaolinbaliu£¨SDRPL£©?Splenic diffuse red pulp small B-cell lymphomaxiangtongpiBxibaolinbaliu/baixuebing£¬banxianzhuheren£¨SBLPN£©?Splenic B-cell lymphoma/leukaemia with prominent nucleoliweibaokuozainei£¬wucibingming£¨disibanbingmingshuyuwei£ºmaoxibaobaixuebingbianyixingheCD5yinxingBxibaoyoulinbaxibaobaixuebing£©linbajiangxibaolinbaliuLymphoplasmacytic lymphomalinbajiangxibaolinbaliu£¨LPL£©?Lymphoplasmacytic lymphomaxiangtong¡¾zhu¡¿baokuoliangzhongyaxing£ºIgM-LPL/WM£¨zuichangjian£¬yuezhan95%£©£ºIgM-LPL/Waldenstromjuqiudanbaixuebing£¨WM£¬huashijuqiudanbaixuezheng£©£»feiWMxingLPL£¨yuezhan5%£©¡£bianyuanqulinbaliuMarginal zone lymphomazhanmoxiangguanlinbazuzhijiewaibianyuanqulinbaliu£©£¨MALT£©?Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissuexiangtongyuanfaxingpifubianyuanqulinbaliu£¨PCMZL£©?Primary cutaneous marginal zone lymphomaweidanduliechu£¨guiruzhanmoxiangguanlinbazuzhijiewaibianyuanqulinbaliu£©linbajiebianyuanqulinbaliu£¨NMZL£©?Nodal marginal zone lymphomaxiangtongertong(linbajie)bianyuanqulinbaliu£¨pNMZL£©?Paediatric (nodal) marginal zone lymphomaxiangtong¡¾zhu¡¿jiepobuweibutong£¬xibaoyichuanxuehejiyintubianpubutong¡££¨1£©linbajiebianyuanqulinbaliu£¨NMZL£©hejiewaibianyuanqulinbaliu£¨EMZL£©jiyintubianpubutong¡££¨2£©jiewaiMZL£¨EMZL£©changjiandebaokuowei¡¢fei¡¢yanfushuqi¡¢tuoyexian¡¢jiazhuangxian¡¢pifudengbuweideMZL£¬butongdejiewaiMZLzhijiancunzaixianzhudeyichuanxuechayi¡££¨3£©pifuMZLjuyoudutedelinchuangbinglitezheng£¬qubieyuqitajiewaiMZL£¨EMZL£©erdanliezuoweidulidejibingshitileixing£¨PCMZL£©¡££¨4£©ertonglinbajiebianyuanqulinbaliu£¨pNMZL£©shicongNMZLxiadeyigeyaxingshengjichengweiyigedulidejibingshitileixing¡£lvpaoxinglinbaliuFollicular lymphomayuanweilvpaoxingBxibaozhongliu£¨ISFN£©?In situ follicular B-cell neoplasmyuanweilvpaoxingzhongliu£¨yuanweilvpaoxingliubian£©lvpaoxinglinbaliu£¨FL£©?Follicular lymphomaxiangtongertongxinglvpaoxinglinbaliu?Paediatric-type follicular lymphomaxiangtongshierzhichangxinglvpaoxinglinbaliu?Duodenal-type follicular lymphomaxiangtongpifulvpaozhongxinlinbaliuCutaneous follicle centre lymphomayuanfaxingpifulvpaozhongxinlinbaliu?Primary cutaneous follicle centre lymphomaxiangtongtaoxibaolinbaliuMantle cell lymphomayuanweitaoxibaozhongliu£¨ISMCN£©?In situ mantle cell neoplasmyuanweitaoxibaoliubiantaoxibaolinbaliu£¨MCL£©?Mantle cell lymphomaxiangtongbaixuebingxingfeilinbajiexingtaoxibaolinbaliu£¨Leukemic non-nodal mantle cell lymphoma£¬feilinbajieMCL£¬nnMCL£©?xiangtong¡¾zhu¡¿feilinbajieMCL£¨nnMCL£©yuMCLxiangbi£¬daduomeiyouzhengzhuang£¬qiyuhouxiangduigenghao£¬zhuyaoshixueye¡¢gusuihepizangshoulei£¬henshaohuozhemeiyoulinbajiezhongda¡£duoxingBxibaolinbaliuzhuanhuaTransformations of indolent B-cell lymphomaduoxingBxibaolinbaliuzhuanhua?Transformations of indolent B-cell lymphomawu¡¾zhu¡¿shoucibaduoxingBxibaolinbaliudegaojibiezhuanhuazuoweiyigedulibufendanlie¡£daBxibaolinbaliuLarge B-cell lymphomas(LBCL)mimandaBxibaolinbaliu£¬feitezhixing£¨NOS£©?Diffuse large B-cell lymphoma(DLBCL),NOSxiangtongfuhanTxibao/zuzhixibaodedaBxibaolinbaliu?T-cell/histiocyte-rich large B-cell lymphomaxiangtongmimandaBxibaolinbaliu/gaojibieBxibaolinbaliu£¬ban MYC he BCL2 zhongpai?DLBCL/HGBL with MYC and BCL2 rearrangementsgaojibieBxibaolinbaliu£¬ban MYC he BCL2 he/huo BCL6 zhongpaiALKyangxingdaBxibaolinbaliu?ALK-positive large B-cell lymphomaxiangtongdaBxibaolinbaliu£¬ban IRF4 zhongpai?Lagre B-cell lymphoma with IRF4 rearrangementxiangtonggaojibieBxibaolinbaliu£¬ban 11q yichang?HGBL with 11q aberrationsBurkittyanglinbaliu£¬ban 11q yichanglinbaliuyangrouyazhongbing?Lymphomatoid granulomatosisxiangtongEBVyangxingmimandaBxibaolinbaliu?EBV-positive diffuse large B-cell lymphomaEBVyangxingmimandaBxibaolinbaliu£¬feitezhixing£¨NOS£©mimandaBxibaolinbaliu£¬banmanxingyanzheng£¨yumanxingyanzhengxiangguandemimandaBxibaolinbaliu£©?Diffuse large B-cell lymphoma associated with chronic inflammationxiangtongxianweidanbai£¨xianweisu£©xiangguandaBxibaolinbaliu?Fibrin-associated large B-cell lymphoma£¨disibanshiyumanxingyanzhengxiangguandemimandaBxibaolinbaliudeyigeyaxing£©tiyeguozaixiangguandaBxibaolinbaliu?Fluid overload-associated large B-cell lymphomawujiangmuxibaolinbaliu?Plasmablastic lymphomaxiangtongyuanfaxingmianyihuomianbuwei£¨tequanbuwei£©daBxibaolinbaliu?Primary large B-cell lymphoma of immune-privileged sites£¨disibanweidandufenxing£¬baokuodi4banzhongdeyuanfazhongshushenjingxitong£¬yuanfaboliti¡¢shiwangmo¡¢zuowandengbuweidemimandaBxibaolinbaliu£©yuanfapifumimandaBxibaolinbaliu£¬tuixing?Primary cutaneous diffuse large B-cell lymphoma,leg typexiangtongxueguanneidaBxibaolinbaliu?Intravascular large B-cell lymphomaxiangtongyuanfazonggedaBxibaolinbaliu?Primary mediastinal large B-cell lymphomaxiangtongzonggehuiqulinbaliu£¨MGZL£©?Mediastinal grey zone lymphomaBxibaolinbaliu£¬wufafenlei£¬tezhengjieyuDLBCLhejingdianhuoqijinlinbaliuzhijiangaojibieBxibaolinbaliu£¬feitezhixing?High-grade B-cell lymphoma(HGBL),NOSxiangtong¡¾zhu¡¿daBxibaolinbaliubaokuoDLBCLfeitezhixingheqita17getedingdaBxibaolinbaliu¡££¨1£©DLBCL£¬NOS?shizuichangjiandeleixing£¬shiyizuyizhixingdelinbaliu£¬qixingtai¡¢biaoxingdengjunbumanzumouzhongtedingdaBxibaolinbaliudezhenduanbiaozhun¡£disibandingyideliangzhongzhuyaoyaxingrengshiyong£¬jixuqufenGCB/ABC£¨GCB/feiGCB£©yaxing¡££¨2£©tiyeguozaixiangguandaBxibaolinbaliu?yeshixinyinrudeleixing£¬zhuyaobiaoxianweitiqiangshoulei£¬zuichangjianshixiongmoqiangshoulei£¬changyoudaozhiyetiguozaidejichujibing£¨manxingxinshuai¡¢shenshuaijie¡¢ganshuaijie/ganyinghuadeng£©£¬duojianyulaonianren£¬yuhouxiangduijiaohao¡£yaozhuyi£¬tayuyuanfaxingshenchuxinglinbaliu£¨PEL£©jiyinbiaodapuheyuhoujunbutong£¬PELyuhougengcha¡£PELmuqianguiruKSHV/HHV8xiangguanBxibaolinbazengzhixingjibinghelinbaliuzheyijiazu/zhongleizhong¡££¨3£©mianyihuomianbuweideyuanfadaBxibaolinbaliu?yexinbanfenleiyinrudeyigexindezongcheng£¬shifashengyumianyigongnengzhengchangrenqundeyizuyuanfaqinxixingBxibaolinbaliu£¬yuanfabuweibaokuozhongshushenjingxitong¡¢bolitishiwangmo¡¢zuowan£ºyuanfaxingzhongshushenjingxitongDLBCL¡¢yuanfaxingzuowanLBCL¡¢yuanfaxingbolitishiwangmoLBCL¡£jianglaikenenghuanhuikuochong£¨biruruxian¡¢pifudeng£©¡££¨4£©zonggehuiqulinbaliu£¨MGZL£©?juyouyuanfazonggeBxibaolinbaliu£¨PMBL£©hejingdianxinghuoqijinlinbaliu£¨cHL£©dezhongdietezheng£¬jinfashengyuzongge£¬shuyudanyishengwuxuetezhengdejibingshiti¡£BurkittlinbaliuBurkitt lymphomaBurkittlinbaliu£¨bojitelinbaliu£©?Burkitt lymphoma(BL)xiangtong¡¾zhu¡¿bojitelinbaliujiwanggenjuliuxingbingxuebeijinghediliweizhifenweisanzhongliuxingbingxueyaxing£ºdifangxingBL¡¢feidifangxing/sanfaxingBL¡¢mianyiquexianxiangguanBL¡£kaolvdaoEBVganranzaizaoqifabingjizhizhongqizhongyaozuoyong£¬jiyufenzitezhengqufenweiliangzhongyaxingqudailiuxingbingxueyaxing£¬ji£ºEBVyangxingBLheEBVyinxingBL¡£KSHV/HHV8xiangguanBxibaolinbazengzhixingjibinghelinbaliuKSHV/HHV8-associated B-cell lymphoid proliferations and lymphomasyuanfaxingshenchuxinglinbaliu£¨PEL£©?Primary effusion lymphomaxiangtongKSHV/HHV8yangxingmimandaBxibaolinbaliu?KSHV/HHV8-positive diffuse large B-cell lymphomaHHV8yangxingmimandaBxibaolinbaliu£¬feitezhixingKSHV/HHV8yangxingshishengfazhongxinlinbazengzhixingjibing?HSHV/HHV8-positive germinotropic lymphoproliferative disorderHHV8yangxingshishengfazhongxinlinbazengzhixingjibing¡¾zhu¡¿KSHV/HHV8£¨kaboxirouliuzuozhenbingdu/renleizuozhenbingdu8xing£©ganranxiangguandelinbazengzhixingjibingbaokuo£ºKSHV/HHV8xiangguandeduozhongxinCastlemanbing£¨KSHV/HHV8-MCD£¬guidaoBxibaoweizhudezhongliuyangbingbianleibiexia£©¡¢yuanfaxingshenchuxinglinbaliu?£¨Primary effusion lymphoma£¬PEL£©¡¢qiangwaiPEL£¨EC-PEL£©¡¢KSHV/HHV8yangxingmimandaBxibaolinbaliu?£¨KSHV/HHV8-DLBCL£©¡¢KSHV/HHV8yangxingshishengfazhongxinlinbazengzhixingjibing?£¨KSHV/HHV8-GLPD£©¡£yumianyiquexianheshidiaoxiangguandelinbazengzhihelinbaliuLymphoid proliferations and lymphomas associated with immune deficiency and dysregulationmianyiquexianxiangguanxingsabazuzhizengshengxingjibingmianyiquexian/shidiao£¨IDD£©yinqideguoduzengsheng?Hyperplasias arising in immune deficiency/dysregulationweilieru£¬disibanbubaokuozainei£¬disibanbaokuofei£¨zuzhi£©pohuaixingyizhihoulinbazengzhixingjibing£¨feipohuaixingPTLD£©dengmianyiquexian/shidiaoyinqideduoxingxinglinbazengzhi£¨duoxingxinglinbazuzhizengzhixingjibing£©?Polymorphic lymphoproliferative disorders arising in immune deficiency/dysregulationweilieru£¨disibanbubaokuozainei£¬baokuoduoxingxingyizhihoulinbazuzhizengzhixingjibing£¨duoxingxingPTLD£©¡¢qitayiyuanxingmianyiquexianxiangguandelinbazuzhizengshengxingjibingdeng£©EBVyangxingpifuzhanmokuiyang?EBV-positive mucocutaneous ulcer(EBVMCU)xiangtongmianyiquexian/shidiaoyinqidelinbaliu?Lymphoma arising in immune deficiency/dysregulationweilieru£¬disibanbubaokuozaineidisibanbaokuodanxingxingyizhihoulinbazuzhizengzhixingjibing£¨danxingxingPTLD£©¡¢jingdianxinghuoqijinlinbaliuyangyizhihoulinbazuzhizengzhixingjibing¡¢HIVganranxiangguanlinbaliudeng£©mianyixiangguanlinbayangzengshenghelinbaliudexiantianxingcuowu£¨xiantianxingmianyiquexianxiangguanlinbazengzhihelinbaliu£¬mianyichushengcuowuxiangguandelinbazengzhihelinbaliu£©?Inborn error of immunity-associated lymphoid proliferations and lymphomaslinbazengzhixingjibingxiangguan£¬banyuanfamianyijibing£¨yuyuanfaxingmianyijibing/quexianxiangguandelinbazengzhixingjibing£©¡¾zhu¡¿mianyiquexian/shidiao£¬mianyiquexianbing£¨immunodeficiency diseases£¬IDD£©shiyizuyouyumianyixitongfayubuquanhuozaoshousunhaisuozhidemianyigongnengquexianyinqidejibing£¬youerzhongleixing£º¢Ùyuanfaxingmianyiquexianbing£¨xiantianxingmianyiquexianbing£©£¬yuyichuanyouguan£¬duofashengzaiyingyouer¡£¢Újifaxingmianyiquexianbing£¨huodexingmianyiquexianbing£©£¬kefashengzairenhenianling£¬duoyinyanzhongganranyouqishizhijieqinfanmianyixitongdeganran¡¢exingzhongliu¡¢yingyongmianyiyizhiji¡¢fangliaohualiaodengyuanyinyinqi¡£yupeixitubianxiangguandeyuanfaxingmianyiquexianbeiguojimianyixuehuilianhehuizhongxinmingmingwei¡°mianyichushengcuowu¡±£¨inborn error of immunity,IEI£©£¨jiwangchengweixiantianxingmianyiquexian£©£¬xinbanWHO-HAEM5fenleicaiyonggaishuyumingcheng¡£huoqijinlinbaliuHodgkin lymphmajingdianxinghuoqijinlinbaliu?Classic Hodgkin lymphma£¨cHL£©xiangtongjiejiexinglinbaxibaoweizhuxinghuoqijinlinbaliu?Nodular lymphocyte predominant Hodgkin lymphma£¨NLPHL£©xiangtong¡¾zhu¡¿huoqijinlinbaliuzaijiubanzhongzuoweidulideleibie£¨category£©£¬Hodgkinxibao£¨RSxibaodedanhebianyixing£©heReed-Sternbergxibao£¨lisixibao£¬RSxibao£¬biaoxianweiduohejuxibao£©qiyuanyushengfazhongxindeBxibao£¬bingkaolvdaodangdaidezhiliaomoshi£¬bahuoqijinlinbaliudandufenchulaideyuhouyiyibuda£¬yincixinbanfenleibahuoqijinlinbaliubeiguidaochengshuBxibaozhongliuleibie£¨category£©xia£¬zuoweichengshuBxibaozhongliudeyigejiazu/zhonglei£¨family/class£©¡£linbaxibaoweizhuxinghuoqijinlinbaliu£¨LPHL£©£¬zhanhuoqijinlinbaliu5%-6%£¬dabufenzaidibeijingxiakejiandaojiejieyangjiegou£¬beijingweixiaolinbaxibaojujimijichengjiejiefenbu£¬xiangsiyulvpaolinbaliu£¬yechengweijiejiexinglinbaxibaoweizhuxingHL£¨NLPHL£©¡£jinyoujishaoshuzhenduanxingdeRSxibao£¬qiechangweiyileichengwei¡°L£¦H¡±RSxibao£¬yechengweiHLdexibaoxibaohe/huozuzhixibaoyaxing£¬yechengwei¡°baomihuaxibao¡±¡£kefashengzairenhenianling£¬zhongweifabingnianling60sui£¬nanxingduojian£¬changqinfanlinbajie£¬yuhoujiaohao¡£mianyizuhuaranseCD30£¨-£©£¬biaodaBxibaokangyuan£¨CD20+£¬CD15-£©¡£kehouqifufa£¬kezhuanhuaweiBxibaoNHL¡£jingdianxinghuoqijinlinbaliu£¨CHL£©£¬juyouxingtaixuedianxingdezhenduanxingRSxibaojiqidanhebianyixing£¨huoqijinxibao£©£¬liuxibaotezhengxingbiaodaCD30+£¬changbiaodaCD15+£¬CE20-¡£baokuosigeyaxing£ºjiejieyinghuaxingcHL£¨NSCHL£©¡¢fuyulinbaxibaoxingcHL£¨LRCHL£©¡¢hunhexibaoxingcHL£¨MCHL£©¡¢linbaxibaoxiaojianxingcHL£¨LDCHL£©¡£jiangxibaozhongliujiqitajuyoufudanbaidejibing£¨12geshiti/leixing£©Plasma cell neoplasms and other diseases with paraproteinsdiwubanfenleidisiban£¨xiuding£©fenleidankelongbingzhongqiudanbaibingMonoclonal gammopathieslengningjisubing£¨CAD£©?Cold agglutinin diseasewuyiyiweimingdeIgMdankelongbingzhongqiudanbaibing?IgM monoclonal gammopathy of undetermined significance£¨IgM MGUS£©xiangtongyiyiweimingdefeiIgMdankelongbingzhongqiudanbaibing?Non-IgM MGUSxiangtongjuyoushenzangyiyidedankelongbingzhongqiudanbaibing?Monoclonal gammopathy of renal significance(MGRS)weilie rudankelongmianyiqiudanbaichenjidejibingDiseases with monoclonal immunoglobulin depositionmianyiqiudanbaixiangguan£¨AL£©dianfenyangbianxing?Immunoglobulin-related(AL) amyloidosisyuanfaxing£¨qinglian£©dianfenyangbianxingdankelongmianyiqiudanbaichenjibing?Monoclonal immunoglobulin deposition diseaseqinglianhezhonglianchenjibingzhonglianbingHeavy chain diseases£¨HCD£©¦Ì£¨Mu£©zhonglianbing?Mu heavy chain diseasexiangtong¦Ã£¨Gamma£©zhonglianbing?Gamma heavy chain diseasexiangtong¦Á£¨Alpha£©zhonglianbing?Alpha heavy chain diseasexiangtongjiangxibaozhongliuPlasma cell neoplasmsjiangxibaoliu?Plasmacytomaxiangtongjiangxibaogusuiliu?Plasma cell myeloma/multiple myelomaxiangtongfuzhongliuzonghezhengxiangguandejiangxibaozhongliu?Plasma cell neoplasms with associated paraneoplastic syndromePOEMS zonghezhengTEMPI zonghezhengAESOP zonghezheng£¨adenopathy and extensive skin patch overlying a plasmacytoma£¬linbajiezhongdaheguangfanpifubankuaibanjiangxibaoliu£©xiangtong£¨danAESOP zonghezhengyiqianbubaokuozainei£©TheNKxibaolinbazengzhixingjibinghezhongliuT-cell and NK-cell lymphoid proliferations and lymphomas£¨39geshiti/leixing£©Txibaoweizhuzhongliuyangbingbian£¨3geshiti/leixing£©Tumor-like lesions with T-cell predominancediwubanfenleidisiban£¨xiuding£©fenleijuchi-tengbenbing?Kikuchi-Fujimoto disease(KFD)wuduoxing T linbamuxibaoxingzengzhi?Indolent T-lymphoblastic proliferation(ITLP)wuzishenmianyixinglinbazengzhizonghezheng?Autoimmune lymphoproliferative syndrome(ALPS)wu¡¾zhu¡¿Txibaoweizhuzhongliuyangbingbianxidiwubanxinyinrudefenlei¡£qiantiTxibaozhongliu£¨2geshiti/leixing£©Precursor T-cell neoplasmsji£ºyuanshiTlinbaxibaobaixuebing/linbaliu£¨Tlinbaxibaobaixuebing/linbaliu£¬Tlinbamuxibaobaixuebing/linbaliu£¬T-lymphoblastic leukaemias/lymphomas£¬T-ALL/LBL£©diwubanfenleidisiban£¨xiuding£©fenleiTlinbamuxibaobaixuebing/linbaliu£¬feitezhixing?T-lymphoblastic leukaemia/lymphoma,NOS£¨T-ALL/LBL£¬NOS£©Tlinbamuxibaobaixuebing/linbaliuzaoqiTqiantilinbamuxibaobaixuebing/linbaliu?Early T-precursor ALL/LBL (ETP-ALL/LBL)zaoqiTqiantilinbaxibaobaixuebing£¨yishanchu£©NKlinbamuxibaobaixuebing/linbaliu£¨yuanshiNKxibaobaixuebing/linbaliu£©¡¾zhu¡¿NKlinbamuxibaobaixuebing/linbaliuzaidisibanfenleizhongzuoweilinshijibingleixing£¬youyuquefamingquedekekaodezhenduanbiaozhunyijixiangguandexingtaixuehemianyibiaoxingtezheng£¬diwubanfenleizhongweidanduliechu¡£chengshuTxibaoheNKxibaozhongliu£¨9gejiazu/zhonglei£¬34geshiti/leixing£©Mature T-cell and NK-cell neoplasms£¨1£©chengshuTxibaoheNKxibaobaixuebing£¨6ge£©£»£¨2£©yuanfaxingpifuTxibaolinbaliu£¨9ge£©£»£¨3£©changdaoTxibaoheNKxibaolinbazengzhihelinbaliu£¨5ge£©£»£¨4£©ganpiTxibaolinbaliu£¨1ge£©£»£¨5£©jianbianxingdaxibaolinbaliu£¨3ge£©£»£¨6£©linbajieTlvpaofuzhuxibaolinbaliu£¨3ge£©£»£¨7£©qitawaizhouTxibaolinbaliu£¨1ge£©£»£¨8£©EBVyangxingNK/Txibaolinbaliu£¨2ge£©£»£¨9£©ertongEBVyangxingTxibaoheNKxibaolinbazengzhihelinbaliu£¨4ge£©¡¾zhu¡¿chengshuTxibaoheNKxibaozhongliugenjuxibaoqiyuan/fenhuazhuangtai¡¢linchuangtezheng¡¢jibingbuwei/weizhi¡¢xibaoxingtaixuedengqufenwei9gejiazu/zhonglei£¬gong34gejibingshiti/leixing¡£daduoshuTxibao¡¢NKxibaozhongliukeguirugezixiangyingdeTxibao¡¢NKxibaopuxi£¬danyoudejibingleixingbaokuoNKxibao¡¢Txibao¡¢hunhehuobuquedingdezhongliubiaoxing£¬TxibaoheNkxibaoqiyuandequfennanyuquedinghuobuqingchu£¬yincidiwubanfenleizhongmeiyoujiandandifenweiTxibaozhongliuheNKxibaolianglei£¬biruchengshuTxibaoheNKxibaobaixuebing¡¢EBV-yangxingjiexingTxibaoheNKxibaolinbaliu¡¢jiewaiNK/Txibaolinbaliudeng¡£diwubanfenleidisiban£¨xiuding£©fenleichengshuTxibaoheNKxibaobaixuebingMature T-cell and NK-cell leukaemiasT-youlinbaxibaobaixuebing£¨T-PLL£©?T-prolymphocytic leukaemiaxiangtongTdakelilinbaxibaobaixuebing£¨T-LGLL£©?T-large granular lymphocytic leukaemiaTxibao£¨dakeli£©linbaxibaobaixuebingNKdakelilinbaxibaobaixuebing£¨NK-LGLL£©?NK-large granular lymphocytic leukaemiaNKxibaomanxinglinbazengshengxingjibingchengren T xibaobaixuebing/linbaliu£¨ATLL£©?Adult T-cell leukaemia/lymphomaxiangtongSezaryzonghezheng£¨saizhalizonghezheng£¬SS£©?S¨¦zary syndromexiangtongqinxixing NK xibaobaixuebing£¨ANKL£©?Aggressive NK-cell leukaemiaxiangtongyuanfaxingpifuTxibaolinbaliuPrimary cutaneous T-cell lymphomasyuanfaxingpifu CD4 yangxingxiao /zhongT xibaolinbazengzhixingjibing?Primary cutaneous CD4-positive small or medium T-cell lymphoproliferative disorderxiangtongyuanfaxingpifuzhiduan CD8 yangxinglinbazengzhixingjibing?Primary cutaneous acral CD8-positive lymphoproliferative disorderyuanfaxingpifuzhiduan CD8 yangxing T xibaolinbaliuzuoyangrouyazhong?Mycosis fungoides(MF)xiangtongyuanfaxingpifuCD30yangxingTxibaolinbazengzhixingjibing£ºlinbaliuyangqiuzhenbing?Primary cutaneous CD30-positive T-cell LPD:Lymphomatoid papulosisxiangtongyuanfaxingpifuCD30yangxingTxibaolinbazengzhixingjibing£ºyuanfaxingpifujianbianxingdaxibaolinbaliu?Primary cutaneous CD30-positive T-cell LPD:Primary cutaneous ALCLxiangtongpixiazhimoyanyangTxibaolinbaliu?Subcutaneous panniculitis-like T-cell lymphomaxiangtongyuanfaxingpifu ¦Ã/¦Ä T xibaolinbaliu?Primary cutaneous gamma/delta T-cell lymphomaxiangtongyuanfaxingpifuCD8yangxingqinxixingshibiaopixibaoduxingTxibaolinbaliu?Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphomaxiangtongyuanfaxingpifuwaizhouTxibaolinbaliu£¬feitezhixing£¨NOS£©?Primary cutaneous peripheral T-cell LPD,NOSwu¡¾zhu¡¿yuanfaxingpifuTxibaolinbaliu£¨CTCL£©shixinbanfenleizhongchengshuT/NKxibaozhongliuleibiexiadeyigezhuanmendejiazu/zhonglei£¬baokuo9gejibingshiti/leixing¡£changdaoTxibaoheNKxibaolinbazengzhihelinbaliuIntestinal T-cell and NK-cell Lymphoid proliferations and lymphomasweichangdaoduoxingTxibaolinbaliu?Indolent T-cell lymphoma of the gastrointestinal tractweichangdaoduoxingTxibaolinbazengzhixingjibingweichangdaoduoxing NK xibaolinbazengzhixingjibing?Indolent NK-cell lymphoproliferative disorder of the gastrointestinal tractwuchangbingxiangguanTxibaolinbaliu?Enteropathy-associated T-cell lymphomaxiangtongdanxingxingshishangpixingchangdao T xibaolinbaliu?Monomorhpic epitheliotropic intestinal T-cell lymphomaxiangtongchang daoT xibaolinbaliu£¬feitezhixing£¨NOS£©?Intestinal T-cell lymphoma ,NOSxiangtong¡¾zhu¡¿weichangdao£¨GI£©duoxingTxibaolinbazengzhixingjibingxinmingmingweiweichangdaoduoxingTxibaolinbaliu£¬mingmingcong¡°linbazengzhixingjibing¡±dao¡°linbaliu¡±dezhuanbian£¬shijiyuqigaofashenglvhejibingdebosanxing£¬danlinchuangguochengrengranmanchang£¬suoyirengbaoliu¡°duoxing¡±zheyixiandingci¡£weichangdaoduoxingNKxibaolinbazengzhixingjibing£¨iNKLPD,indolent NK-cell lymphoproliferative disorder£©shixinzengleixing£¬jiwangrenweishiyizhongfanyingxingguochengerchengweilinbaliuyangweibinghuoNKxibaochangbing£¬danzuijindefaxianzhichitadezhongliuxingtezheng£¬yincixinyinruzuoweiyigedulidejibingshiti/leixing¡£ganpiTxibaolinbaliuHepatosplenic T-cell lymphomaganpiTxibaolinbaliu£¨HSTCL£©?Hepatosplenic T-cell lymphomaxiangtongjianbianxingdaxibaolinbaliuAnaplastic large cell lymphomaALK-yangxingjianbianxingdaxibaolinbaliu?ALK-positive anaplastic large cell lymphoma£¨ALK+ALCL£©jianbianxingdaxibaolinbaliu, ALK-yangxingALK-yinxingjianbianxingdaxibaolinbaliu?ALK-negative anaplastic large cell lymphoma£¨ALK-ALCL£©jianbianxingdaxibaolinbaliu, ALK-yinxingrufangzhiruwuxiangguanjianbianxingdaxibaolinbaliu?Breast implant-associated anaplastic large cell lymphoma£¨BIA-ALCL£©xiangtong¡¾zhu¡¿jianzhibianxingdaxibaolinbaliu£¨ALCL£©jiazubaokuo3gejibingshiti/leixing£ºALK+ALCL¡¢ALK-ALCL¡¢BIA-ALCL¡£junweichengshuTxibaolinbaliu£¬CD30qiangbiaoda£¬tongchangbubiaodaTxibiaozhiwu¡£yuanfaxingpifuALCLmeiyouguizaigaijiazuxia£¬ershiguileidaolingyijiazu¡°yuanfaxingpifuTxibaolinbazengzhihelinbaliu¡±xia£¬qiyuquanshenxingALK-ALCLxiangbiyuhougengjia¡£rufangzhiruwuxiangguandeALCLshiyizhongbutongyuqitaALK-ALCLdejibingleixing£¬shiyizhongfeiqinruxingzhongliu£¬yucucaobiaomianrufangzhiruwuxiangguan£¬linchuangyuhouxiangduijiaohao£¬danruguoqinfanlinjinjiegouzeyuhoubiancha¡£linbajieTlvpaofuzhu(TFH)xibaolinbaliuNodal T-follicular helper(TFH) cell lymphomalinbajieTFHxibaolinbaliu£¬xueguanmianyimuxibaoxing?Nodal TFH cell lymphoma ,angioimmunoblastic-type£¨nTFHL-AI£©xueguanmianyimuxibaoxingTxibaolinbaliu£¨AITL£©linbajieTFHxibaolinbaliu£¬lvpaoxing?Nodal TFH cell lymphoma ,follicular-type£¨nTFHL-F£©lvpaoxingTxibaolinbaliulinbajieTFHxibaolinbaliu£¬feitezhixing?Nodal TFH cell lymphoma ,NOS£¨nTFHL-NOS£©juyouTFHbiaoxingdejiexingwaizhouTxibaolinbaliu¡¾zhu¡¿linbajielvpaofuzhuxingTxibaolinbaliu£¨nTFHL£©jiazubaokuo3gejibingshiti/leixing£¬junxilinbajieTxibaolinbaliu£¬juyouTFH£¨lvpaofuzhuxingTxibao£©debiaoxinghejiyinbiaodatezheng¡£nTFHL-AI£¬angioimmunoblastic-type duiyingyuyiqiande¡°xueguanmianyimuxibaoxingTxibaolinbaliu¡±nTFHL-F£¬ollicular-type duiyuyingyuyiqiande¡°lvpaoTxibaolinbaliu¡±nTFHL-NOS duiyingyuyiqiande¡°juyouTFHbiaoxingdewaizhouTxibaolinbaliu¡±qitawaizhouTxibaolinbaliuwaizhouTxibaolinbaliu£¬feitezhixing£¨NOS£©?Peripheral T-cell lymphoma,not otherwise specified(NOS)xiangtong¡¾zhu¡¿PTCL-NOSshiyizuyizhixinghenqiangdejibing£¬shipaichuxingzhenduan£¬tebieyaojianbienTFHL¡£EBVyangxingNK/TxibaolinbaliuEBV-positive NK/T-cell lymphomasEBVyangxingjiexingTxibaoheNKxibaolinbaliu?EBV-positive nodal T- and NK-cell lymphomawujiewaiNK/Txibaolinbaliu£¨ENKTL£©?Extranodal NK/T-cell lymphomajiewaiNK/Txibaolinbaliu£¬bixing¡¾zhu¡¿jiewaiNK/Txibaolinbaliu£¨ENKTL£©kefashengzaibutongdejiewaibuwei£¬yincishanchujiubanzhongdexiandingci¡°bixing¡±¡£EBVyangxingjiexingTxibaoheNKxibaolinbaliujiwangbeiguiruPTCL-NOSxiadeyigeyaxing£¬zaixinbanfenleizhongzuoweiyigedulidejibingshiti/leixing£¬zhuyaofashengzaidongyarenzhong£¬yuhoucha¡£ertongEBVyangxingTxibaoheNKxibaolinbazengzhihelinbaliuEBV-positive T- and NK-cell lymphoid proliferations and lymphomas of childhoodyanzhongwenchongdingyaoguomin?Severe mosquito bite allergyxiangtongzhongdouyangshuizuobinglinbazengzhixingjibing?Hydroa vacciniforme LPD(HVLPD)zhongdouyangshuizuobingyang£¨Hydroa vacciniforme-like£©linbazengzhixingjibingxitongxingmanxinghuodongxingEBVjibing£¨xitongxingCAEBVD£©?Systemic chronic active EBV diseaseTxibaoheNKxibaoleixingdemanxinghuodongxingEBVganran£¬xitongxingertongxitongxingEBVyangxingTxibaolinbaliu?Systemic EBV-positive T-cell lymphoma of childhoodxiangtong¡¾zhu¡¿£¨1£©manxinghuodongxingEBVbing£¨CAEBVD£©£ºbaokuojuzaozhengzhuanghe/huoduoxingxingshideyanzhongwenchongdingyaoguomin?heHVLPDjingdianxing?£¬yijiquanshenxingjibingHVLPDquanshenxing?hexitongxingCAEBVD?¡££¨2£©ertongxitongxingEBVyangxingTxibaolinbaliu?Hydroa vacciniforme£¨zhongdouyangshuizuobing£¬douchuangyangshuizuobing£©linbazuzhidejianzhiyuanxingzhongliuStroma-derived neoplasms of lymphoid tissues£¨7geshiti/leixing£©diwubanfenleidisiban£¨xiuding£©fenleijianzhishutuxibaozhongliuMesenchymal dendritic cell neoplasmslvpaoshutuxibaorouliu?Follicualr dendritic cell sarcomaxiangtongEBV-yangxingyanxinglvpaoshutuxibaorouliu?EBV-positive inflammatory follicular dendritic cell sarcomayanxingjialiuyanglvpao/chengxianweixibaoshutuxibaorouliuxianweimuxibaowangzhuangxibaoliu?Fibroblastic reticular cell tumorxiangtongjixianweimuxibaoliuMyofibroblastic tumourjieneizhalanzhuangjixianweimuxibaoliu?Intranodal palisaded myofibroblastomawupiteyixingxueguanjianzhizhongliuSpleen-specific vascular-stromal tumourspixueguanjianzhiliuSplenic vascular-stromal tumourspizuoanxibaoxueguanliu?Littoral cell angiomawupicuogouliu?Splenic hamartomawupiyinghuaxingxueguanliuyangjiejiexingzhuanhua?Sclerosing angiomatoid nodular transformation of spleenwu¡¾zhu¡¿1¡¢linbazuzhijianzhiyuanxingzhongliudemouxieleixingshilinbajiehuopizangsuoteyoude£¬guirubenfenleitixizhong¡£feilinbajiehepizangteyixingderuanzuzhizhongliu£¨biruxueguanliu¡¢xueguanrouliu¡¢linbaguanjiliu¡¢kaboxirouliudeng£©guidao2020niandiwubanWHOguheruanzuzhizhongliufenleizhong¡£2¡¢linbazuzhijianzhi£¨jizhi£©laiyuanzhongliushidiwubanxinyinrudefenlei£¬gaileibiexiabaokuosandalei£º£¨1£©jianzhishutuxibaozhongliu£ºcong¡°zuzhixibaoheshutuxibaozhongliu¡±leibiezhongyiguolaidelvpaoshutuxibaozhongliu£¨?he?£©hechengxianweiwangzhuangxibaozhongliu?guiruzheyixinleibiemingxia£¨yinweilvpaoshutuxibaobingfeiyuanzizaoxueganxibao£¬ershijianzhilaiyuan£©¡£lingwai£¬EBVyangxingyanxinglvpaoshutuxibaorouliu?youyujuyoudutedelinchuangbinglitezheng£¬conglvpaoshutuxibaorouliu?zhongdanliechulaizuoweidulidejibingleixing¡££¨2£©jixianweimuxibaoliu£¬xilinbajieteyixingjianzhizhongliu£¨linbajieneizhalanzhuangjixianweimuxibaoliu?£©¡££¨3£©piteyixingjianzhizhongliu£¬baokuo£ºpizuoanxibaoxueguanliu?¡¢picuogouliu?¡¢piyinghuaxingxueguanliuyangjiejiexingzhuanhua?£©¡£shutuxibaohezuzhixibaozhongliuDendritic cell and histiocytic neoplasms£¨11geshiti/leixing£©diwubandisiban£¨xiuding£©fenleijiangxibaoyangshutuxibaozhongliuPlasmacytoid dendritic cell neoplasmsyusuixizhongliuxiangguandechengshujiangxibaoyangshutuxibaozengzhiMature plasmacytoid dendritic cell proliferation associated with myeloid neoplasmwumuxibaoxingjiangxibaoyangshutuxibaozhongliuBlastic plasmacytoid dendritic cell neoplasmwulanggehansixibaoheqitashutuxibaozhongliuLangerhans cell and other dendritic cell neoplasmslanggehansixibaozhongliuLangerhans cells neoplasmslanggehansixibaozuzhixibaozengshengzhengLangerhans cell histiocytosisxiangtonglanggehansixibaorouliuLangerhans cell sarcomaxiangtongqitashutuxibaozhongliuOther dendritic cell neoplasmsweidingleishutuxibaoliuIndeterminate dendritic cell tumourxiangtong£¨weiquedingshutuxibaozhongliu£©zhituzhuangshutuxibaorouliuInterdigitating dendritic cell sarcomaxiangtong£¨jiaozhishutuxibaorouliu£©zuzhixibaozhongliuHistiocytic neoplasmsyounianhuangserouyazhongJuvenile xanthogranulomaxiangtong£¨bosanxingyounianhuangserouyazhong£©Erdheim-Chesterbing£¨ECD£©Erdheim-Chester diseasexiangtongRosai-Dorfmanbing£¨RDD£©Rosai-Dorfman diseasewuALKyangxingzuzhixibaozengshengzhengALK-positive histiocytosiswuzuzhixibaorouliuHistiocytic sarcomaxiangtong¡¾zhu¡¿zuzhixibao/shutuxibaozhongliuzaixinbanfenleitixizhongdingweiyusuixizhongliuzhihou£¬tongchangrenweitamenqiyuanyuchangjiandesuixizuxibao£¨suixizuxibaochanshengdanhexibao/zuzhixibao/shutuxibaopuxi£©¡£disibanzuzhixibao/shutuxibaozhongliuxiade¡°lvpaoshutuxibaorouliu¡±¡¢¡°chengxianwei£¨xianweimuxibao£©wangzhuangxibaozhongliu¡±£¬kaolvdaoshiyoulinbajizhixibaochanshengdezhongliu£¬diwubanfenleijiangqicongzuzhixibao/shutuxibaozhongliuzhongfenchulaiguirudaolinxizhongliu¡°linbazuzhijianzhiyuanxingzhongliu¡±xia¡£cankaowenxian£º£¨1£©The 5th edition of the World Health Organization Classifification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms. Leukemia(2022) 36:1703-1719.https://doi.org/10.1038/s41375-022-01613-1.£¨2£©The 5th edition of the World Health Organization Classifification of Haematolymphoid Tumours: Lymphoid Neoplasms. Leukemia(2022) 36:1720-1748.https://doi.org/10.1038/s41375-022-01620-2.

´Ó(°ä´Ç²Ô²µ)¡°¾ø(´³³Ü±ð)Íû(°Â²¹²Ô²µ)ÎÄ(°Â±ð²Ô)ä(²Ñ²¹²Ô²µ)¡±µ½(¶Ù²¹´Ç)°Â(´¡´Ç)ÔË(³Û³Ü²Ô)ÊÜ(³§³ó´Ç³Ü)Ñû(³Û²¹´Ç)Õß(´Ü³ó±ð)£ºÍõ(°Â²¹²Ô²µ)Ò»(³Û¾±)²©(µþ´Ç)µÄ(¶Ù±ð)Äæ(±·¾±)Ï®(³Ý¾±)Ö®(´Ü³ó¾±)·(³¢³Ü)

¾ÝÁ˽⣬ÎÒÊ¡È«ÃæÂäʵȫ¹úͳһµÄÆû³µ±¨·Ï¸üв¹ÌùÕþ²ß£¬²¢¸ù¾Ý¡¶º£ÄÏÊ¡Íƶ¯Ïû·ÑÆ·ÒԾɻ»ÐÂÐж¯ÊµÊ©·½°¸¡·£¬Öƶ¨³ǫ̈¡¶Ï¸Ôò¡·£¬ÔÚȫʡͬʱʵʩÆû³µÖû»¸üв¹ÌùÕþ²ß¡£¸ù¾Ý¡¶Ï¸Ôò¡·£¬×Ô¸ÃϸÔòÓ¡·¢Ö®ÈÕ£¨2024Äê5ÔÂ15ÈÕ£©ÖÁ2024Äê9ÔÂ30ÈÕ£¬¸öÈËÏû·ÑÕßתÈ㨲»º¬±ä¸üµÇ¼ÇºÍ±¨·Ï£©2024Äê5ÔÂ15ÈÕÇ°µÇ¼ÇÔÚ±¾ÈËÃûϵÄÎÒÊ¡³ËÓ󵣬²¢ÔÚº£ÄÏʡע²áµÇ¼ÇµÄ¹«Ë¾¹ºÂòÐÂÄÜÔ´³ËÓóµÐ³µ£¬°´ÕÕ¡°Ã¿×ªÈÃÒ»Á¾¾É³µ²¢¹ºÂòÒ»Á¾Ð³µ¿ÉÏíÊÜÒ»´Î²¹Ìù¡±Ô­Ôò£¬¸ù¾Ý¹ºÂòгµ½ð¶î£¨»ú¶¯³µÏúÊÛͳһ·¢Æ±º¬Ë°¼Û£©¸øÓè¸öÈËÏû·ÑÕßÏàÓ¦µÄÒ»´ÎÐÔ¹º³µ²¹Ìù£º¶Ô¼Û¸ñÔÚ10ÍòÔª£¨²»º¬£©ÒÔϵģ¬²¹Ìù3000Ôª£»10ÍòÔª£¨º¬£©ÖÁ20ÍòÔª£¨²»º¬£©µÄ£¬²¹Ìù4000Ôª£»20ÍòÔª£¨º¬£©ÖÁ30ÍòÔª£¨²»º¬£©µÄ£¬²¹Ìù5000Ôª£»30ÍòÔª£¨º¬£©ÒÔÉϵģ¬²¹Ìù6000Ôª¡£²»ÔÜ·ÏÆ·ºó£¬¼Ò±äÊæÊÊÁË£¬ÐÄÇéÒ²Ê泩ÁË¡£ÀúÊ·¾ç¡¶Ð¡Èª²Ê¥¹¥Ú¥·¥ã¥ëÍêÈ«ÓÀ¾Ã±£´æ°æ¡·ÊÖ»ú¸ßÇå...

ÉúÈÕÅɶԽáÊøºó²»¾ÃÀÁÀÁÓÖ×ö³öÁËÒ»¸öÁîÈ˾ªÑȵľٶ¯£ºËý·ÉÍùÁËÈÕ±¾¶øËýµÄÄ¿µÄµØÕýÊÇÍõ˼´ÏËùÔڵijÇÊÐ

ÉùÃ÷£º¸ÃÎĹ۵ã½ö´ú±í×÷Õß±¾ÈË£¬ËѺüºÅϵÐÅÏ¢·¢²¼Æ½Ì¨£¬ËѺü½öÌṩÐÅÏ¢´æ´¢¿Õ¼ä·þÎñ¡£