91视频专区

朱智勋冲朱智勋介绍冲图片冲作品-猫眼电影韩国美女主播朴妮唛视频全集种子分享

为啥娶俄国媳妇?中俄混血娃质问妈妈:你俩幸福,孩子里外不是人

2024年12月17日,风险提示:本基金管理人承诺以诚实信用、勤勉尽责的原则管理和运用基金财产,但不保证基金一定盈利,也不保证最低收益。因基金分红导致基金份额净值变化,不会改变基金的风险收益特征,不会降低基金投资风险或提高基金投资收益。基金的过往业绩不代表未来表现,基金管理人所管理的其他基金的业绩并不构成对本基金业绩表现的保证。投资有风险,敬请投资者认真阅 读基金的、、等相关法律文件,了解基金的风险收益特征,并根据自身的风险承受能力选择适合自己的基金产物。

朱智勋冲朱智勋介绍冲图片冲作品-猫眼电影韩国美女主播朴妮唛视频全集种子分享

据报道这个秘密地堡位于乌克兰西部利沃夫附近地下80米-120米深处是北约用来控制防空系统的战略指挥所地堡里驻扎了共300多人有40人为高级外国专家其中包括多名退休的北约军官和顾问他们大多是英国人和波兰人但其中也有美国人和支持通信、数据传输的私营公司代表

宽坐圈人生该怎么走原创2022-02-11 08:30·热情的高山A人一出生就面临各种人生考验。经过这个过程,悲伤和眼泪、喜怒哀乐、悲欢离合很多。但是他们更累了。随着社会生活节奏的加快,人们忙着如何赚更多的钱,却忘记了他们来到这个世界是为了什么。(约翰f肯尼迪,金钱)很多人在讨论这个问题,很多人在深思。他们说的是一系列的东西,其实没有什么变化。这说明了问题。人只是体现价值,追求体面、舒适、尊严的生活就足够了。当一个人只对事业没有爱时,他会多么孤独。他的人生道路黯然失色。爱情是婚姻。一辈子在一起。但是婚姻在一定程度上约束着两个人。就像戴着爱的手铐遵守合同一样。如果你结婚,你会体验到这种感觉。如果你在寻找意志和爱。戴手铐的你,请发挥好自己的作用。不要强词夺理,做个好妻子,做个好丈夫。不管穷还是富,都要互相依靠。只有经历了人生的坎坷,才能对自己负责。(威廉莎士比亚,哈姆雷特,家人)爱情之路能否走得更远,取决于我们改变了多少。遇到问题,请放松心情,以便所有的不快都能轻松解决。(伯纳德肖,)如果你太在意,你会失去很多东西。不如静下心来多晒太阳。因为阳光总是温暖的。来到这个世界,不要太客气。你想吃什么就吃什么,但不能吃。如果你存1美元,损失10美元,当你找到平衡点的时候,你会感觉舒服很多。如果找不到疏浚的理由,就好好睡一觉,做个好梦。人终必死亡。想想你活着的时候该做什么。幸福的生活离不开珍惜的爱。

feijiroujinrunxingrutouzhuangniaolushangpizhongliudeduocanshufenlei:jiehexingtaixue、biaoxinghefenzitezhengyigaijinfengxianfenceng2023-03-14 01:51·yixuejingjieSander P, Harland N, Serna-Higuita LM, Bonzheim I, B?smüller H, Stenzl A, Fend F. Multiparametric Classification of Non-Muscle Invasive Papillary Urothelial Neoplasms: Combining Morphological, Phenotypical, and Molecular Features for Improved Risk Stratification. Int J Mol Sci. 2022 Jul 23;23(15):8133. doi: 10.3390/ijms23158133. PMID: 35897708; PMCID: PMC9330009.yi、jianjiebangzuoaishishijieshangzuichangjiandeaizhengzhiyi,meinianyueyou 550,000 li [ 1 ]。jiezhizhenduanshi,dayue 75% debangzuoaishidijibie、feijicengjinrunxingrutouzhuangzhongliu,beichengweifeijicengjinrunxingbangzuoai (NMIBC) [2 ]。NMIBC baokuoqinfanguyoucenghejiedizuzhiderutouzhuangzhongliu,anzhao TNM fenleifenwei T1、Ta he Tis。genjuqixingtaitezheng,zhexiezhongliukejinyibufenweidijibiehegaojizhongliu。dijibiezhongliu Ta he T1 zai 5 niansuifangzhongjingchangfufa (31–78%) danhenshaojinzhanweijinrun (shaoyu 1% he 45%),yinciyuhoulianghao [3 , 4 , 5 ]。lingyifangmian,gaojibierutouzhuangzhongliukenengfazhanweijicengjinrunxingbangzuoai (MIBC),houzhetongchanghuifazhanweizhuanyi [ 6]]. yinci,zainiaolushangpiaidezhiliaozhong,binglifenjidequedingzhizaijiangzhongliufenweibutongdeyuhouzu,yipingguzhiliaojieguobingyouhuahuanzheguanli。zhenduibangzuofeiqinruxingrutouzhuangbingbiandebinglifenjitichuliaojizhongfenjixitong [ 7 ]。1973 niande WHO fenleijiangbangzuoniaolushangpiaifenwei G1、G2 he G3 ji;raner,youyuzhezaidingyi G2 zhongliufangmiancunzaiyixiejuxianxing,yincitabei 2004/2016 WHO fenleixitongsuoqudai [ 8]. gaixitongrujinguangfanyongyuduibutongzuzhixueyazuzhongdefeijiroujinrunxingniaolushangpiliuxingchengjinxingqiangyoulidefenlei,baokuodiduexingqiannengderutouzhuangniaolushangpiliu,chengwei PUN-LMP、dijibierutouzhuangfeijinrunxingniaolushangpiai (LG-PUC) hegaojibierutouzhuangfeijinrunxingai (HG-PUC)。raner,gaifanganyegeijieshidailailiaoyixiekunnan,daozhiguanchazhejiandebianyixingxiangduijiaogao,zai PUN-LMP binglizhongwei 12-39%,zai LG-PUC zhongwei 21-63%,zai HG-PUC zhongwei 18-56% .jinnianlaisuizhuoxinyidaicexujishudechuxian,bangzuoaidezhenduanbujinguanzhuxingtaixue,huanguanzhufenzitezheng。zai UROMOL yanjiuzhong,NMIBC zhongliugenjuqizhuanlutezhengfenweisanlei,xianshichuxibaozhouqijiyinhefenhuabiaozhiwubiaodadechayi [9 ]。ciwai,longdedaxuexiaozugenjukejihuodebaxianghezhuanluyinziquedingliaowugebutongdeshiti,baokuo Uro A、jiyinzubuwending、jinrunxing SCC yanghe Uro B yaxing [10],tamendazhiduiyingyujidiheguanqiangbeikaluolainadaxuefenleizhongmiaoshudeyazu [ 11]. zhexiefenziyaqunyibiandefeichangzhongyao,yinweitamenyulinchuangyuhouzhijiexiangguan,danshangweijinrulinchuangshijian 。NMBIC huanzhedechangguizhiliaoshijingniaodaobangzuozhongliuqiechushu (TURBT),lianhehuobulianhekajiemiao (BCG) bangzuoneizhiliaoyijiangdijinzhanfengxian。raner,jinguan BCG zhiliaoyouxiao,60% dehuanzhekenengzai 12 geyuehoufufa,20% dehuanzhekenengjinzhanwei MIBC。buchenggongde BCG zhiliaohuanzhexuyaogenzhixingbangzuoqiechushuhuohuaxueliaofahefangsheliaofa,zheliangzheduyuxiangdangdadefabinglvxiangguan。yinci,xuyaoqitaliaofa,rumianyijianchadianyizhijihejiyuqifenzipudeliaofalaigaishanbangzuoaidefabinglv 。zaizhexiangyanjiuzhong,womencongzuzhibinglixue、mianyibiaoxinghetubianzhuangtaidengsangebutongcengmianyanjiuliaofeiqinruxing PUC detezheng,zhizaijinxingzhunquehewenjiandefenlei。gaifenleibaokuoshiyongxingtaixuetezheng、baokuo CK20、p16、p21、p53、MIB-1、yousifenliebiaojiwu p-HH3 he FGFR3(chengxianweixibaoshengchangyinzishouti)demianyizuzhihuaxuezu,yijiyufufahefufaxiangguanjiyindebaxiangtubianfenxi。yuhou,baokuoFGFR3、TP53、PTEN、PIK3CA、ERCC2heSTAG2。2. jieguo2.1. duiliemiaoshubenyanjiugongnaru 45 lifeijinrunxingniaolushangpirutouzhuangliubianhuanzhe,zuichufenleiwei pTa,zuzhizhilianglianghao,shihejinyibufenxi。linchuangxinxizongjieyubiaoge1. nannvbiliwei 2.75:1,zhongweinianlingwei 75 sui(fanwei 50-95 sui)。genju TNM fenlei,39/45 (86.6%) huanzhebeiguileiweichun pTa,er 6/45 (13.3%) huanzhezailingyigebuweiyou pT1 bingbian。19 li (42.2%) zaibangzuodelianggehuogengduoquyuxianshiduogezhongliudingwei,er 26 lixianshidangebingbian。budaoyibandehuanzhefufa (48.4%),zhiyou 52.6% dehuanzhezailiangniandesuifangzhongmeiyoufufa。genju 44 minghuanzhedexianyoulinchuangshuju,zhiyou 25/44 (56.8%) huanzhejieshouliaolijizhiliao,13/44 (29.5%) huanzhejieshouliaoliji MMC dizhu。suoyouzuzhixue HC-PUC zhenduandehuanzhe (12/44, 27.3%) junjieshouliaozai TUR-BT zhiliao,19 ming (19/44, 43.2%) huanzhejinjieshouyixueguanchadanweigeiyuzhiliao。biaoge1).biaoge1feijinrunxingniaolushangpirutouzhuangliubianbinglidelinchuangtezheng。n = 45 (%)zhongweinianling(fanwei) 75 sui (50–95)xingbie n (%)nanxing 33 (73.3)nvxing 12 (26.6)M:Fbilv 2.75:1zhongliufenqi,TNM n (%)pTa 39 (86.6)pTa he pT1 6 (13.3)zhongliudingwei2 gehuogengduoweizhi 19 (42.2)cebi 10 (22.2)houbi 6 (13.3)sanlengshu 3 (6.6)jingbu/dingdian 3 (6.6)bangzuoyuanding 2 (4.4)qianbi 2 (4.4)zuzhixuehuandengpianzhongdebiniaoji 30 (66.7)zhenduanhoulijizhiliao * ( n = 44) n (%)wuzhiliao 19 (43.2)lijibangzuoneidizhuMMC 12 (27.3)zhongxinTUR-BT 13 (29.5)liangniansuifangzhongdefufalv % * 48.4%linchuangguochengzhongdejinyibuzhiliaowuxujinyibuzhiliao 12 (27.3)jinyibude BCG huo MMC dizhu 10 (22.7)TUR-B 31 (70.5)bangzuoqiechushuhe TUR-B: 2 (4.5)bangzuoqiechushu、TUR-B he BCG zhiliao 2 (4.5)zaidandudechuangkouzhongdakaiMMC:siliemeisuC;BCG,kajiemiao(BCG);TUR-BT,jingniaodaobangzuozhongliuqiechushu。* baifenbishizhendui 44 minghuanzhejisuande,yinwei 1 lihuanzhedeyixielinchuangshujubukeyong。2.2. zuzhixuefenleiduiyuanshizhenduanheyuanshizhenduanbaogao (ODR) buzhiqingdesanweibinglixuejiadezhenduanyizhixingshujubaogaoyubiao 2. PUN-LMP zhenduandeguanchazhejianbianyixingshizhong (57%),LG-PUC binglilianghao (67%),HG-PUC binglijihao (87%)。zaibijiao PUN-LMP he LG-PUC zhenduanshifaxianliaozuixianzhuodeguanchazhejianbianyixing,Fleiss Kappa zhishuxiangdangdi,wei 0.43 ( p= <0.001),95% zhixinqujianzai 0.398–0.635 zhijian。dangzhishaoyouliangmingduliguanchayuandachengyizhiyijianshi,jiujianliliaogongshizhenduan。genjugongshi,zhiyou 18% debinglibeiguileiwei PUN-LMP,danyiban(51.1%)dehuanzheshuyu LG-PUC leibie,33.3% dehuanzhebeiguileiwei HG-PUC。zaihouxuxingdongzhong,ruyuqidenayang,zai HG-PUC binglizhongguanchadaogenggaodefufalv。yu LG he HG-PUC de 23 geyuehe 5 geyuexiangbi,PUN-LMP debinglixianshichugenggaodezhongweiwufufa(34 geyue)。liangnianfufafenxixianshi,yu LG-PUC (42.7%) he PUN-LMP (33.3%) xiangbi,HG-PUC defufalv (79.5%) genggao(p = 0.14,tu1). genjubuchongbiao S2zhongdegongshizhenduanmiaoshujixianlinchuangtezhenghesuifang。tu1zuzhixuefenjihewufufashengcun。(yi)。daibiaoxingzuzhixuetuxiangxianshibutongzhongliudengji(PUN-LMP、LG-PUC he HG-PUC)dezhuyaotezheng。(yi)。tongguogongshizhenduanbijiaozhongliufenjidewufufashengcunqide Kaplan-Meier fenxi。(bing)。bijiao TNM fenleihezhongliufenjidewufufashengcunqide Kaplan-Meier fenxi。PUN-LMP,diduexingqiannengderutouzhuangniaolushangpiliu;LG-PUC,dijibieniaolushangpirutouzhuangai;HG-PUC,gaojibieniaolushangpirutouzhuangai。biao 2WHO 2004/2016 zuzhixueleibiezhijiandeguanchazhejianbianyixing。nianji wangshangzhengyijiejue zhenduan P 1 zhenduan P 2 zhenduanP 3 gongshizhenduan guanchazhejianbianyixing (%) fulaisikapaPUN-LMP 18 (40%) 16 (35.6%) 8 (17.8%) 6 (13.3%) 8 (17.8%) 57% 0.43 **LG-PUC 14 (31.1%) 15 (33.3%) 22 (48.9%) 27 (60%) 23 (51.1%) 67% 0.41 **HG-PUC 13 (28.9%) 14 (31.1%) 15 (33.3%) 12 (26.7%) 14 (31.1%) 87% 0.81 **zaidandudechuangkouzhongdakaiPUN-LMP,diduexingqiannengderutouzhuangniaolushangpiliu;LG-PUC,dijibieniaolushangpirutouzhuangai;HG-PUC,gaojibieniaolushangpirutouzhuangai;P 1、2、3,binglixuejia 1、2 he 3。** pzhi < 0.001 Fleiss Kappa。2.3. mianyizuhuatezhengjiyuzhongliufenjidexiangguanxingSpearman dezuzhipingfendengjixiangguanjuzhenzaizhenduanleibiezhijianmeiyouzhengxiangguan,chuliaozengzhizhishu,tayu p-HH3 ransepinggudeyousifenliejishuchengzhengxiangguan(tu 2). CK20、p53 hezengzhilv (MIB-1) shishibiejuyoujiaogaozuzhixuefenjihebulianghouguodebinglideheshigongju。zhesangebiaozhiwuzai LG-PUC he HG-PUC binglizhongxianshichubi PUN-LMP bingligenggaodezuzhipingfen ( p < 0.05) (biao3hetu 2). zhongliuyizhiyinzi p53 zaisangeyazuzhongxianshiyizhiranse,danyu PUN-LMP xiangbi,zaifenleiwei LG-PUC he HG-PUC debinglizhongbiaoxianchugenggaodebiaoda ( p = 0.06)。ciwai,yu LG- huo HG-PUC binglixiangbi,guileiwei PUN-LMP debinglixianshi CK20、p53 ransejiaoruo,p-HH3 pinggudezengzhiheyousifenlielvjiaodi(p< 0.001)。yu HG-PUC zuxiangbi,LG-PUC binglixianshichuxiangside CK20 he p53 zuzhipingfen。xiangbizhixia,HG-PUC binglidezengzhilv (MIB-1) heyousifenliejishudefenjiaogao。yixie PUN-LMP he LG-PUC binglixianshiyousifenliejishujiaogao,danzaizhexiebinglizhong,yu HG-PUC xiangbi,yousifenliejinxianyujidiceng。xibaozhouqidanbai p21 he p16 zaibinglizhongransebujunyun,yuzuzhixuefenjiwuxiangguanxing。zonggongyou 28/37 (75.7%) gebinglixianshisuoyoubinglijunquefa FGFR3 ranse,danfenleiwei LG-PUC de 6 gebingli (6/20, 30%) xianshi FGFR3 guobiaoda。yibaneryan,zhiyou 16/25 (64%) debinglixianshiquefayuqitubianzhuangtaixiangguande FGFR3 biaoda,yinweiyixietubiankenengdaozhifeigongnengxingdanbaizhi。tu 2mianyizuzhihuaxuetezheng。(yi)。sipiermandengjixiangguanjuzhenhemianyizuzhihuaxuebianliangdexiangguanyiyi。zhixianshi Spearman paimingjieguo;lansebiaoshizhengxiangguan,hongsebiaoshifuxiangguan。(yi)。xiaotiqintubijiaoliaofeiqinruxing PUC leibiezhongyong p-HH3 ransede 10 gegaobeishiye (HPF) zhongdeyousifenliejishu。(bing)。mianyizuzhihuaxuebiaojiwudebutongzuzhipingfendexiaotiqintu,biaoshifeiqinruxing PUC shiti。duiyutongjifenxi,shiyongweipeiduitjianyan,ns= buxianzhuo,* p < 0.05,** p < 0.01,**** p < 0.0001。biao3genjuzuzhixuefenjidebinglidezuzhipingfen。CK20 MIB-1 p-HH3 * FGFR3 p16 p21 p53PUN-LMP 60(6–180) 3(3–30) 2(1–12) 9(1–40) 10(15–270) 150(60–170) 90(50–130)LG-PUC 202(110–270) 25(9–45) 10(5–15) 70(10–82.5) 85(17.5–180) 110(57.5–160) 127.5(100–182.5)HG-PUC 225(172–270) 90(57–97.5) 38.5(25.3–51.5) 26.3(10–82.5) 25(3–225) 97.5(6–191.3) 142.5(97.5–210)pzhi 0.027 <0.001 <0.001 0.032 0.065 <0.001 0.066zaidandudechuangkouzhongdakaizuzhipingfenzhongweishu (p25–p75);PUN-LMP,diduexingqiannengderutouzhuangniaolushangpiliu;LG-PUC,dijibieniaolushangpirutouzhuangai;HG-PUC,gaojibieniaolushangpirutouzhuangai。* 10 gegaobeishiye (HPF) zhongdeyousifenlieshu。2.4. tubianjingguanzonggongyou 37 geanlishiyongbaxiang NGS jinxingliaofenxi。cexudepingjunduqushenduwei 6820 ciduqu (1141–23,628)。tubiandefenbumiaoshuyutu 3buchongbiao S1zhongzongjieliaoxiangxixinxi。zonggongjiandingchu 80 getubian,66/80 gecuoyidiantubian (82.5%),9 gewuyitubian (11.25%) he 5 geyimatubian (6.25%)。SIFT、PolyPhen-2 he CADD defenxiyuceliaoduisuoyoubaogaodecuoyitubiandepohuaixingyingxiang。suoyoujiyintubiandebianyidengweijiyinpinlv (VAF) fanweiwei 3% zhi 93%(pingjun 34%)。tu 3(yi)。meigezhenduanleibiedetubianhemianyizuzhihuaxuejieguogaishu。(yi)。lianggehesangezizu(fenbieweiyoucehezuoce)dejuleifenxi。(bing)。shiyongjuleituzhongxianshidejuleifenxidewufufashengcunde Kaplan-Meier tu。yufenjiwuguan,FGFR3shigaixiliezhongshouyingxiangzuipinfandejiyin。guileiwei PUN-LMP debinglizhuyaoxianshiFGFR3gaibian (57%, 4/7) bingqiemeiyouTP53tubian。ciwai,zaiERCC2、PTENhePIK3CAzhongjiancedaodetubiandaduoshitongshifashengde,bingqiezongtishangbuchangjian (28.5%, 2/7)。dijibie PUC binglizai 17/20 (85%) binglizhongtongyangbiaoxianchupinfandeFGFR3tubian,11 libinglizaiPIK3CA (63.6%, 7/11)、STAG2 (54.5%, 6/11) heERCC2 (45.4%)zhongbiaoxianchubingfagaibian, 5/11). TP53tubiancunzaiyu 2/20 (10%) binglizhong。HG-PUC binglixianshijiaodipinlvdeFGFR3gaibian (40%, 4/10) hegengduoTP53gaibian (30%, 3/10)。TP53tubianbinglizongshixianshichugaoTP53zuzhipingfen,danxiangfan,bingfeisuoyoujuyougaozuzhipingfendebinglidubiaoxianchuTP53jiyingaibian。PTENtubianhenshaojian,dancunzaiyu PUN-LMP he HG-PUC binglizhong。zaisuoyoudiaochadejiyinzhong,zhiyouTP53tubianyuwufufashengcunxianzhuoxiangguan(p = 0.024,buchongtu S1)。2.5. zhenghexingtaixue、mianyibiaoxinghetubianzhuangtaidejuleifenxijuleifenxiqingchudijiangfeiqinruxingrutouzhuangniaolushangpizhongliufenweilianggebutongdeyazu。julei 1 daibiao PUN-LMP he LG-PUC binglidehunhe,xianshidizengzhilvheyousifenliejishu,yijipinfandeFGFR3he STAG2 tubian,erjulei 2 baohanjuyougaozengzhizhishuheyousifenliejishude HG-PUC,qiang CK20 biaoda, TP53tubiandanFGFR3 WT (biao 4). juleifenxiyulinchuangxingweimiqiexiangguan,bingxianshiyudi 1 zu(fenleiwei PUN-LMP he LG-PUC debingli)xiangbi,di 2 zu(fenleiwei HG-PUC debingli)dewufufashengcunlvjiaodi,( p = 0.029 ,tu 3gongyuanqian)。shiyongsangebutongdeyazujinxingewaidejuleifenxiyiqueding PUN-LMP he LG-PUC binglishifoukeyifenkai。(tu 3B,zuoce)。raner,zaidi 1 zuhedi 2 zuzhongfaxianliao PUN-LMP he LG-PUC hunhebingli,bingqiegaicuyuzuzhixuefenjiwuguan。jihusuoyouguileiwei HG-PUC debinglidubeishoujidaodi 3 zu(tu 3B、C,zuoce)。biao 4juleizhijiandanbaizhihetubianzhuangtaidebijiao。biaoji jiqun 1 jiqun 2 p -zhimianyizuzhihuaxue zhongweishu (p25–p75) zhongweishu (p25–p75) Wilcoxon zhihejianyanCK20 160 (80–240) 225 (172.5–270.0) 0.150p53 110 (80–160) 158.7 (107.5–212.5) 0.013MIB-1 15 (3–33.9) 90 (68.5–97.5) <0.001FGFR3 60 (1–80) 3 (1.0–65.0) 0.101p-HH3 * 8 (3–12) 38.5 (25.7–51.5) <0.001tubianzhuangtai n (%) n (%) χ2jianyan_FGFR3 18 (40.0%) 3 (6.0%) 0.028STAG2 8 (17.2%) 1 (2.2% 0.236TP53 2 (4.4%) 5 (11.1%) 0.023ERCC2 7 (15.5%) 4 (8.8%) 0.717PIK3CA 10 (22.2%) 3 (6.6%) 0.724zaidandudechuangkouzhongdakaimianyizuzhihuaxue:shujubiaoshiweizuzhipingfenzhidezhongweishu (p25–p75) huo (*) 10 HPF zhongdeyousifenlieshu。tubianzhuangtaiyoutubianbinglishu (%) biaoshi。Kaplan-Meier fenxixianshiyujiqunyouhenqiangdexiangguanxing,yinweidi 1 zuhedi 2 zudewufufashengcunlvshizhongjiaogao,LG-PUC he PUN-LMP zhijiancunzaizhongdie (p = 0.055 )。di 3 zushizhongxianshichujiaogaodefufalv(tu 3C,zuomianban)。zhixingbili Cox huiguimoxingyiguji RFS hejuleifenxizhijiandeguanlian。danbianliangheduobianliangfenxizhengshilinchuangtezhenghezhiliaobuyingxiang RFS。RE-TURB zhiliaobiaoshiyufufaxianzhuoxiangguan,danweikaolv,yinwei RE-TURB jinzai HG-PUC binglizhongjinxing(buchongbiao S4)。duobianliangfenxizhengshi,linchuangtezhenghezhiliaobuyingxiangwufufashengcun,bingqiefufayuyouzuzhixuetezheng、danbaizhibiaodahetubianzhuangtaichanshengdecuzudulixiangguan(buchongbiao S5 he S6 )。3.taolunzaizhexiangyanjiuzhong,womencaiyongliaofeiqinruxingrutouzhuangniaolushangpizhongliudeduocanshufenlei,baokuotubianzhuangtai、mianyibiaoxinghezuzhibinglixue,yishitugaijindanduzuzhixuefenjidefengxianpinggu。zaizhiqianhewomenmuqiandefenxizhong,rutouzhuangniaolushangpizhongliudefenjijuyouchadaozhongdudeguanchazhejiankezhongfuxing。raner,zhongliudejingquefenjiduiyuzhiliaojuecehejiangdifufaheqinxidefengxianzhiguanzhongyao [ 2 , 17 ]。fenjidechayikenengshiyouyuduifenjidexingtaixuetezheng(jiegou、xibaoxue、yousifenliedeng)fuyubutongdequanzhong,jinguanduocichangshimingquedingyifenjibiaozhun [18 ]]. raner,zhongsuozhouzhi,fenjixitongzongshishejiyidingchengdudezhuguanxing,yingxiangguanchazhejiandezaixianxing。zairutouzhuangniaolushangpizhongliuzhong,zuikunnandetiaozhanshi PUN-LMP yu LG-PUC dequbie,yinweizheliangzhongshitidujuyoudianxingderutouzhuangjiegou,jibeiniaolushangpifugaiderutouquefadingduanyousifenliehuodong,weiyidedingyitezhengshicunzaiheshangpiyixinghewenluandeshuliang,keyizhuguanpinggu。zai PUN-LMP deqingkuangxia,niaolushangpikanqilaigenghou,danshijishangyinggaipaichufeidianxingxing,erzai LG-PUC deqingkuangxia,rutouzaidifangdabeishuxiaxianshichuyouxudewaiguan,bingqiecunzaifeidianxingxingdanqingwei [ 19 , 20]. zaiwomendeyanjiuzhong,yuwenxianyizhi,PUN-LMP biaoxianchuzuidichengdudeguanchazhejianyizhixinghekezhongfuxing,bingqiezhenduan LG-PUC erbushi PUN-LMP dequshizengjia。ciwai,zaibijiao PUN-LMP he LG-PUC shi,fufalvdechayixiangduixiangsi。PUN-LMP binglidefufalvyinwenxianzhongdeyanjiueryi,kenengshiyizhongshoufenleibiaozhunyingxiangdejieguo。PUN-LMP defufalvwei 17% zhi 35%,LG-PUC wei 48-71%,HG-PUC binglidefufalvwei 78%。xiangbizhixia,PUN-LMP deqinxifengxianwei 1-3%,LG-PUC wei 5%,HG-PUC bingligaoda 45% [ 21 ]。youyuzuzhixuetezhengbiaoxianchumingxiandejuxianxing,yinciyanjiuliaoqitagongju,ruyousifenliejishu、zengzhilvheteyixingmianyizuzhihuaxuebiaojiwudebiaoda,zuoweiduiniaolushangpizhongliujinxingfenjidefuzhufangfa。shiyongtongguobandingliangfangfapinggudeyousifenliehuoxingdeyanjiubiaoming,fenjidekezhongfuxingdi,bingqieyuyuhoudexiangguanxingcha [ 18 ]。raner,duiruxianaideyanjiubiaoming,keyitongguodingliangfangfagaishanyousifenliejishu [ 22]]. zaiwomendeyanjiuzhong,shiyong p-HH3 mianyiransejinxingyousifenliejishuyijianshaozhuguanxing,jinguanbixutidao p-HH3 ransebunengzhijieyu H&E qiepianshangdeyousifenliejishujinxingbijiao。zaisuoyou HG-PUC binglizhongjunguanchadaogaoyousifenliezhishu(10 HPF zhong > 20 ciyousifenlie),biaoming p-HH3 deyousifenliejishushifenjideyouyongcanshu。tongguo MIB-1 ransepinggudezengzhilvyeshiyigeyouyongdetezheng,dan PUN-LMP he LG-PUC zhijiandezengzhilvchayixiweiqiezhongdie,yinciwufajiangqiyongzuofenjideweiyicanshu [23 ]。yixiezuozhebaodaoliao CK 20 he p53 ransezuoweiniaolushangpifayubuliangdekeguanbiaozhi [ 24]. CK20 tongchangjinzaizhengchangniaolushangpidesanzhuangxibaozhongbiaoda,ermimanxingquanceng CK20 ranseshi HG-PUC detezheng [ 25 ]。raner,zai PUN-LMP he LG-PUC binglizhongbaodaoliaobuyizhide CK20 biaoda;yinci,buyingdandushiyongcicanshu [ 26 ]。jinnianlai,qiangdadegaotongliangcexujishudechuxianshiwomenduiniaolushangpiaitubianqingkuanghetedinggaibiandeyuhouyingxiangdelijiequdeliaozhongdajinzhan,congerdaozhiliaobangzuoaidejizhongfenzifenlei。jubaodao,NMIBC shijiyinzuwendingdezhongliu,qitezhengshiFGFR3tubianhuoransetiyiwei(zaidayue 70%dedijibiezhongliuzhong)[ 27、28 ],zhekenengdaozhizaoqiniaolushangpizengsheng [ 29 ]。yuzhexieshujuyizhi,FGFR3tubianshiwomenxiliezhongzuichangjiandeyichuangaibian(64.1% debingli)。zhengruyuqidenayang,FGFR3tubianyufeigaojibiaoxingxiangguan。PIK3CAzhongdejihuotubianhezhanliandanbaifuhewuzhongliuyizhijiyinSTAG2zhongdeshihuotubiansihuzaifabingjizhizhongqiciyaozuoyong,yinweidaduoshuzhexietubianyuFGFR3gaibiantongshifasheng[ 30、31、32 ],zhengruzaidaduoshubenyanjiuzhongdeanli。zhebiaomingPIK3CAheSTAG2gaibianbenshenyudijinzhanfengxianxiangguan [ 33 , 34 ]。xiangfan,gaojirutouzhuangaihejinrunxingzhongliujingchangxianshiTP53degaibian、ERCC2hePTENjiyinhetonglu [ 35、36 ]。henshaofaxianzhibingxingTP53tubian,danruguocunzai,tamenjinzai LG- he HG-PUC zhongbeishibie,yuqitaaizhengyiyang,daibiaoexingzhongliudeyichuantezheng [ 37、38 ]。DNA jiexuanmeiERCC2,zhiqianbeimiaoshuwei MIBC zhongshunbozhiliaominganxingdeshengwubiaozhiwu,tongyangsihuzaibangzuoaidefashengzhongfahuizuoyong [ 39 , 40 ]。raner,zhengrubenxiliezhongsuoguanchadaode,tayekeyizaisuoyouleibiede NMIBC zhongshibiechulai。yiaijiyinPTENyu NMIBC (40%) xiangbi,zai MIBC (90%) zhongdabufenjiyinshihuo [ 41 ]。raner,zaigaixiliezhong,zai PUN-LMP binglizhongyefaxianliaoshihuodePTEN (2/4 binglifashengtubian)。juyouPTENhuoTP53tubiandehanjian PUN-LMP he LG-PUC bingli(tongchangyugaojibiezhongliuxiangguan)shifouxianshichugenggaodejinzhanfengxianhuanyoudaiguancha。zaiwomendezhuchengfenfenxizhongduimianyizuzhihuaxuehefenzibiaozhiwudelianhepinggushiwomennenggoushibiechujuyouxianzhuobutongjinzhanfengxiandeliangzu,jinguanbinglishulianghenshao。ciwai,zhezhongshiyongduogecanshudejuleifenxibiaoming PUN-LMP he LG-PUC miqiexiangguan,kenengdaibiaoliaoyixilieshengwuxuexingwei。jianyu PUN-LMP he LG-PUC shiyongxiangtongdelinchuanghezhiliaofangfa,muqianjiyuzuzhixuetezhengbingzaiqijieshizhongjuyouxiangdangdadezhuguanxingdequfendejibenyuanlishangbuqingchu,xuyaoduigengduobinglijinxingjinyibufenxi[ 19 , 21 , 42 , 43]. caiyongewaidedanbaizhiheyichuanbiaojideduocanshufenxikeyongyu NMIBC fenji,bingkenenggaishanlinchuangxingweideyuceyijifufahejinzhandefengxian。yinggaijinshenjieshizhexiangyanjiudejieguo,yinweizhexiangyanjiuzhidaibiaoliaoyouxianshuliangdehuanzhe,qizhongzhifenxiliaoyouxianshuliangdedanbaizhibiaozhiwuhetubian。zhexianggongzuozhuyaobiaoshiyuanliyanjiudezhengming,qizhongdezhuyaomubiaoshibiaomingduocanshufangfajuyouyixieyouxiwangdejieguo,yinggaizaigengdadeduiliezhongjinxingceshi。zaigexinghuayiliaoshidai,jiancetubianhuoqimianyizuzhihuaxuetidaiwudefenzizuduiyuxuanzezuijialiaofaheyucebangzuoaihuanzhedeyuhouzhiguanzhongyao。youyu PUN-LMP he UPC daibiaobangzuoaihuanzhelinchuangguochengzhongdezaoqizhenduan,yincitamendeduocanshufenxi(baokuodanbaizhishengwubiaozhiwuhetubianpufenxi)henyouxiwang,yinggaizaigengdadeduiliezhongjinxing。si、cailiaoyufangfa4.1. zhongliuyangbenzaizhexiangyanjiuzhong,womennaruliaotubingendaxueyiyuanbinglixueheshenjingbinglixueyanjiusuozai 2013 nianzhi 2020 nianjianzhenduanweifeijinrunxingrutouzhuangniaolushangpizhongliudesuoyouyangben,zhexieyangbenfuhewomendexuanzebiaozhun:rutouzhuangfeijiroujinrunxingbangzuoaihuanzhedehuojianfenjizuowei PUN-LMP、LG-PUC huo HG-PUC。xuanzedaibiaoxingkuaijinxingfenxi。ciwai,19 gemeiyouzhongliuhuofayuyichangdebangzuohuojianyangbenyongzuoyinxingduizhao。benyanjiujingtubingendaxueyixueyuanlunliweiyuanhuipizhun (547/2021BO2)。4.2. genju 2016 nian WHO fenleidezuzhixuefenleiweiliaogenju WHO 2016 nianfenleijinxingzhongxinfenlei,sanweibinglixuejiamangmupingguliaoyongsumujingheshuhong (HE) ransede 3 ?m houqiepian。binglibeifenleiwei PUN-LMP、feiqinruxing LG-PUC huo HG-PUC。zaidi、zhonghegaofangdabeishu(100×、200× he 400×)xiajinxingxibaoxuehejiegoutezhengdepinggu[ 8、44]. PUN-LMP beizhenduanweijuyoulisanderutou、xichangqieweironghedebingli,dabufenbeizhengchangdeniaolushangpixibaofugai,xibaoxueyixingxing、yousifenliehehuaisijishaohuobucunzai。feiqinruxing LG-PUC huojianxianshiniaolushangpixiabanbufenpailieyouxuderutou,juyouqingduxibaoxueyixinghehanjiandeyousifenlie。feiqinruxing HG-PUC binglizaidibeijingxiabiaoxianchuwanquanwuxudewaiguan,zheshiyouyuzhenggeshangpigaodudejiegouwenluan、zhongduzhigaoduyixingheyousifenliehuodong [44 ]。4.3. linchuangshujushenchaliaoyiliaojilu,baokuonianling、xingbie、jibingbiaoxian、weizhi、fanwei、TNM fenqi、zhiliaohesuifang。wufufashengcunqi (RFS) shicongzhenduanriqidao 5 nianhuozuihouyicisuifangjisuande。4.4. mianyizuzhihuaxuegenjuzhizaoshangdefangan,shiyongzidongranseji(Ventana Medical Systems,Tucson,AZ,USA)jinxingmianyiranse。daidianzaibopianyong CK20 (M7019, Dako Cytomation, Glostrup, Denmark), p16 (06594441001, CINtech, Roche, Manheim, Germany) p21 (556431, BD Pharmigen, San Jose, CA, USA), p53 (DO-7 , Novocastra, Leica Biosystems, Wetzlar, Germany), MIB-1 (M7240, Dako Cytomation, Glostrup, Denmark), p-HH3 (117C826, IMGENEX, San Diego, CA, USA) he FGFR3 (sc-13121, Santa Cruz Biotechnology ,deguohaidebao)。mianyizuzhihuaxueshiyongzuzhipingfenjinxinglianghua,ruxiasuoshu。genjuqiangduhexibaobaifenbiduiransejinxingpingfen。zaimohexibaozhizhongpingguqiangdubingpingfenwei 0:yinxing,+:ruo,++:zhongdeng,+++:qiang。ranhoutongguojiangranseqiangduchengyiyangxingransexibaodebaifenbilaijisuanzuzhipingfen。ciwai,p-HH3 mianyizuzhihuaxueyongyujiandingzhengzaijingliyousifenliedexibao。tongguojisuan 2 mm zhongransexibaodeshulianglaipingguransetu 2,shiyong Zeiss Axioskop xianweijing(Zeiss,Oberkochen,Deutschland)duiniaolushangpideshangcengjinxingdayue 10 gelianxudegaobeishiye [HPF]。4.5. DNAtiqugenjuzhizaoshangdeshuoming,shiyong Maxwell ? RSC DNA FFPE shijihehe Maxwell ? RSC yiqi(Promega,meiguoweisikangxingzhoumaidixunshi)congshengyudehuojiancailiaozhongtiqujiyinzu DNA 。genjuzhizaoshangdefangan,shiyong Qubit dsDNA HS jianceshijihe(Thermo Fisher Scientific,Waltham,MA,USA)de Qubit yingguangjidui DNA jinxingdingliang。ruxianqianbaodaodenayang,jinxingzhiliangkongzhijuhemeilianfanying (PCR) yiquedingkekuozengde DNA changdu [ 45]。xuanzejuyouzhishao 200 bp kekuozeng DNA debinglijinxing NGS baxiangfenxi。4.6. baxiangxiayidaicexubaxiangtubianfenxiyouxiayidaicexu (NGS)(Ion GeneStudio S5 prime,Thermo Fisher Scientific,Waltham,MA,USA)shiyong AmpliSeq Custom Panel jinxing,hangairutouzhuangfeijiroujinrunxingniaolushangpibangzuoaizhongzuichangjiandefufatubianjiyin(wanzhengdebianmaxulie:ERCC2、FGFR3、PIK3CA、PTEN、STAG2heTP53(buchongbiao S1). genjuzhizaoshangdeshouceshiyong Ion AmpliSeq Library Kit v2.0、Ion Library TaqMan Quantitation Kit、Ion 510、Ion 520 he Ion 530 Kit—Chef he Ion 520 Chip Kit jinxingkuozengziwenkuzhibeihebandaoticexu(Thermo Fisher Scientific,meiguomasazhusaizhouwoersemu)。wulishilabaomaiderutouzhuangfeijiroujinrunxingniaolushangpibangzuoyongyuyanzheng NGS mianban。yurenleicankaoxuliexiangbi,feitongyitixibaobianyidebianyidiaoyongshishiyong Ion Reporter ruanjian(Thermo Fisher Scientific,Waltham,MA,USA)jinxingde。4.7. juleifenxijinxingjuleifenxiyiquedingjuyouxiangsixingdehuanzhezu。jindui 37 lijinxingliaofenxi,yinwei 8 lihuanzhedeshujuqueshi。zhixingbianliangbiaozhunhua (Versi) yihuodelingjunzhiheyibiaozhuncha。juleifenxijiyuyixiabianti:zuzhixuefenlei(PUN-LMP、LG-PUC he HG-PUC)、mianyizuzhihuaxue(CK20、p53、MIB-1、p16、p21、FGFR3 he p-HH-3)hetubianERCC2 , FGFR3 , PIK3CA , PTEN , STAG2 , TP53zhuangtai(tubianyufeitubian)。K-Medoids jiqunde Partitioning around Medoids (PAM) suanfayongyugenjuhuanzhedexiangsixingduihuanzhejinxingfenzu,yinweigaisuanfaduizaoshengheyichangzhibutaimingan。zaizhezhongfangfazhong,meigejiqunduyoujiqunzhongdeyigeshujudianbiaoshi。zhexiedianbeimingmingweicuzhongxindian(cuzhongdeduixiang,qiyucuzhongsuoyouqitachengyuanzhijiandepingjunchayizuixiao)。[ 46 , 47 ]。shiyongoushijulijisuanlianggeshizhixiangliangzhijiandejuli,qidingyiruxia:4.8. tongjifenxishiyong R ruanjianbanben 4.0(R tongjijisuanjijinhui,weiyena,aodili)jinxingtongjifenxi。shiyongpinlvhebilimiaoshufenleibianliang;shuzhibianliangbaogaoweijunzhihebiaozhuncha (±SD) huozhongweishuhesifenweiju (IQR),jutiqujueyushujudefenbu。tongguoyanjiufengdu、pianduhe QQ tulaipinggufenbudezhengtaixing。shiyongkafangjianyanpinggufenleibianliang。zhixing Fleiss de Kappa ceshiyiceliangguanchazhejiandebianyixing。tongguo Kaplan-Meier fangfafenxiwufufashengcun (RFS),bingshiyongduishuzhijianyanlaijianyanzujianchayi。suifangdingyiweicong 24 geyuedaojieguofashenghuoyiqitafangshishanshideshijian。shiyongdanbianliangheduobianliang Cox bilifengxianhuiguilaipinggujiqunhewufufashengcunzhijiandeguanlian。duobianliangmoxingdehouxuanfengxianyinsushigenjulinchuangkaolvheshuangbianliangfenxidetongjixuexianzhuojieguoxuanzede。zhixingxianghouxuanzeyicongmoxingzhongshunxushanchubianliang。tongguojuzhenxiangguanjianchaduozhonggongxianxing。jieguobaogaoweifengxianbihe 95% zhixinqujian。shiyong Schoenfeld canchapinggubilifengxianjiashe。suoyoutongjijianyandushishuangcede,bingqie duobianliangmoxingdehouxuanfengxianyinsushigenjulinchuangkaolvheshuangbianliangfenxidetongjixuexianzhuojieguoxuanzede。zhixingxianghouxuanzeyicongmoxingzhongshunxushanchubianliang。tongguojuzhenxiangguanjianchaduozhonggongxianxing。jieguobaogaoweifengxianbihe 95% zhixinqujian。shiyong Schoenfeld canchapinggubilifengxianjiashe。suoyoutongjijianyandushishuangcede,bingqie duobianliangmoxingdehouxuanfengxianyinsushigenjulinchuangkaolvheshuangbianliangfenxidetongjixuexianzhuojieguoxuanzede。zhixingxianghouxuanzeyicongmoxingzhongshunxushanchubianliang。tongguojuzhenxiangguanjianchaduozhonggongxianxing。jieguobaogaoweifengxianbihe 95% zhixinqujian。shiyong Schoenfeld canchapinggubilifengxianjiashe。suoyoutongjijianyandushishuangcede,bingqiep < 0.05 beirenweibiaomingjuyoutongjixueyiyi。5。jielunzaiguoqudejishinianzhong,jieheaizhengzhenduanzhongbutongfuzachengdudefenleiyichengweizhongliujiancehefencengdezhongyaogongju。tamenyulinchuangxingweiyouhenqiangdexiangguanxing,bingtigongshengwuxuedongchaliheduizhongliudelijie,zhexiezhongliuzaikezhongfufenlei(ru PUN-LMP)zhongxianshichukunnan。zaizhexianggongzuozhong,womenqueren PUN-LMP he LG-PUC zhijiandejigezuzhixue、mianyibiaoxingheyichuantezhengxianshizhongdie,yefanyingzaikekaodifenlizhelianggeshitidekunnanshang。zhezuizhongdaozhiliao PUN-LMP he LG-PUC shifoudaibiaoshengwulianxutidewenti,zuzhixuefenjiweinengchongfenbozhuodaozheyidian,xuyaotianjiafenzihebiaoxingtezhengzuoweifuzhugongjuyigenghaodijinxingfengxianfenceng。【douya+doumiao+paocai+zuomaimian+xianggu+jixiongrou】

三(San)条(Tiao)弹(Dan)射(She)器(Qi)亮(Liang)了(Liao)!003航(Hang)母(Mu)海(Hai)试(Shi)? 央(Yang)视(Shi)公(Gong)开(Kai)最(Zui)新(Xin)画(Hua)面(Mian): 拖(Tuo)船(Chuan)带(Dai)出(Chu)港(Gang)池(Chi)首(Shou)发(Fa)2024-01-03 00:09·星(Xing)辰(Chen)大(Da)海(Hai)路(Lu)上(Shang)的(De)种(Zhong)花(Hua)家(Jia)#文(Wen)章(Zhang)首(Shou)发(Fa)挑(Tiao)战(Zhan)赛(Sai)#1月(Yue)2日(Ri)晚(Wan),社(She)交(Jiao)媒(Mei)体(Ti)上(Shang)突(Tu)然(Ran)疯(Feng)传(Chuan)一(Yi)张(Zhang)003航(Hang)母(Mu)“福(Fu)建(Jian)舰(Jian)”“海(Hai)试(Shi)”的(De)照(Zhao)片(Pian),在(Zai)多(Duo)艘(Sou)拖(Tuo)船(Chuan)的(De)拖(Tuo)带(Dai)下(Xia),003航(Hang)母(Mu)驶(Shi)出(Chu)港(Gang)池(Chi),前(Qian)往(Wang)不(Bu)明(Ming)目(Mu)的(De)地(Di),有(You)网(Wang)友(You)表(Biao)示(Shi)003航(Hang)母(Mu)这(Zhe)是(Shi)要(Yao)去(Qu)海(Hai)试(Shi)了(Liao),也(Ye)有(You)网(Wang)友(You)认(Ren)为(Wei),这(Zhe)次(Ci)003航(Hang)母(Mu)是(Shi)去(Qu)干(Gan)船(Chuan)坞(Wu)做(Zuo)最(Zui)后(Hou)的(De)检(Jian)查(Cha),不(Bu)日(Ri)即(Ji)将(Jiang)海(Hai)试(Shi)!央(Yang)视(Shi)公(Gong)开(Kai)最(Zui)新(Xin)画(Hua)面(Mian):拖(Tuo)船(Chuan)带(Dai)出(Chu)港(Gang)池(Chi),目(Mu)的(De)地(Di)在(Zai)哪(Na)里(Li)?央(Yang)视(Shi)《新(Xin)闻(Wen)联(Lian)播(Bo)》公(Gong)开(Kai)画(Hua)面(Mian),必(Bi)须(Xu)要(Yao)去(Qu)看(Kan)看(Kan),直(Zhi)接(Jie)翻(Fan)到(Dao)央(Yang)视(Shi)新(Xin)闻(Wen)联(Lian)播(Bo)直(Zhi)播(Bo)频(Pin)道(Dao),半(Ban)小(Xiao)时(Shi)的(De)进(Jin)度(Du)条(Tiao),给(Gei)我(Wo)拉(La)了(Liao)三(San)次(Ci)才(Cai)找(Zhao)到(Dao),各(Ge)位(Wei)想(Xiang)看(Kan)的(De)注(Zhu)意(Yi)了(Liao),在(Zai)19点(Dian)11分(Fen)33秒(Miao),只(Zhi)有(You)4秒(Miao)左(Zuo)右(You)的(De)时(Shi)间(Jian),一(Yi)闪(Shan)而(Er)过(Guo)哦(O),难(Nan)怪(Guai)笔(Bi)者(Zhe)三(San)次(Ci)才(Cai)找(Zhao)到(Dao),当(Dang)然(Ran)不(Bu)想(Xiang)那(Na)么(Me)麻(Ma)烦(Fan)的(De)朋(Peng)友(You)就(Jiu)直(Zhi)接(Jie)看(Kan)如(Ru)下(Xia)动(Dong)图(Tu),压(Ya)缩(Suo)了(Liao)一(Yi)大(Da)半(Ban),效(Xiao)果(Guo)也(Ye)算(Suan)不(Bu)错(Cuo)了(Liao),凑(Cou)合(He)着(Zhuo)看(Kan)吧(Ba):非(Fei)常(Chang)明(Ming)显(Xian)的(De)可(Ke)以(Yi)看(Kan)出(Chu)来(Lai),003航(Hang)母(Mu)的(De)状(Zhuang)态(Tai)应(Ying)该(Gai)是(Shi)出(Chu)港(Gang)池(Chi)不(Bu)远(Yuan),附(Fu)近(Jin)的(De)码(Ma)头(Tou)上(Shang)系(Xi)泊(Bo)的(De)船(Chuan)只(Zhi)还(Huan)占(Zhan)了(Liao)画(Hua)面(Mian)一(Yi)角(Jiao),但(Dan)究(Jiu)竟(Jing)前(Qian)往(Wang)哪(Na)里(Li)却(Que)成(Cheng)了(Liao)一(Yi)个(Ge)问(Wen)题(Ti),有(You)网(Wang)友(You)认(Ren)为(Wei)是(Shi)海(Hai)试(Shi),不(Bu)过(Guo)社(She)交(Jiao)媒(Mei)体(Ti)上(Shang)的(De)意(Yi)见(Jian)更(Geng)多(Duo)的(De)还(Huan)是(Shi)认(Ren)为(Wei)去(Qu)干(Gan)船(Chuan)坞(Wu)进(Jin)一(Yi)步(Bu)测(Ce)试(Shi)的(De)概(Gai)率(Lv)更(Geng)大(Da)。福(Fu)建(Jian)舰(Jian)既(Ji)然(Ran)都(Du)已(Yi)经(Jing)准(Zhun)备(Bei)完(Wan)毕(Bi)了(Liao):还(Huan)要(Yao)进(Jin)干(Gan)船(Chuan)坞(Wu)干(Gan)嘛(Ma)?答(Da)案(An)是(Shi)进(Jin)行(Xing)“最(Zui)后(Hou)一(Yi)步(Bu)”的(De)刮(Gua)船(Chuan)底(Di)等(Deng)相(Xiang)关(Guan)清(Qing)洁(Jie)工(Gong)作(Zuo),估(Gu)计(Ji)还(Huan)将(Jiang)对(Dui)船(Chuan)底(Di)的(De)部(Bu)分(Fen)附(Fu)属(Shu)设(She)备(Bei)进(Jin)行(Xing)最(Zui)后(Hou)的(De)检(Jian)查(Cha)工(Gong)作(Zuo),央(Yang)视(Shi)公(Gong)布(Bu)的(De)正(Zheng)是(Shi)进(Jin)入(Ru)4号(Hao)船(Chuan)坞(Wu)前(Qian)的(De)拖(Tuo)带(Dai)画(Hua)面(Mian)。进(Jin)入(Ru)干(Gan)船(Chuan)坞(Wu)后(Hou)将(Jiang)会(Hui)摆(Bai)正(Zheng)船(Chuan)体(Ti),然(Ran)后(Hou)关(Guan)上(Shang)船(Chuan)坞(Wu)门(Men)排(Pai)干(Gan)水(Shui)进(Jin)行(Xing)清(Qing)理(Li)工(Gong)作(Zuo)。福(Fu)特(Te)号(Hao)在(Zai)干(Gan)船(Chuan)坞(Wu)内(Nei)注(Zhu)水(Shui)的(De)场(Chang)景(Jing)还(Huan)有(You)一(Yi)个(Ge)非(Fei)常(Chang)重(Zhong)要(Yao)的(De)工(Gong)作(Zuo)要(Yao)做(Zuo),在(Zai)拖(Tuo)船(Chuan)拖(Tuo)带(Dai)的(De)过(Guo)程(Cheng)中(Zhong),各(Ge)位(Wei)应(Ying)该(Gai)发(Fa)现(Xian)了(Liao),甲(Jia)板(Ban)上(Shang)除(Chu)了(Liao)三(San)条(Tiao)弹(Dan)射(She)器(Qi)以(Yi)外(Wai)还(Huan)没(Mei)有(You)跑(Pao)道(Dao)以(Yi)及(Ji)停(Ting)机(Ji)坪(Ping)与(Yu)各(Ge)种(Zhong)指(Zhi)示(Shi)线(Xian)条(Tiao),因(Yin)此(Ci)在(Zai)干(Gan)船(Chuan)坞(Wu)中(Zhong)很(Hen)有(You)可(Ke)能(Neng)会(Hui)进(Jin)行(Xing)划(Hua)线(Xian)等(Deng)工(Gong)作(Zuo),从(Cong)12月(Yue)30日(Ri)开(Kai)始(Shi)算(Suan)起(Qi),这(Zhe)个(Ge)1月(Yue)11日(Ri)海(Hai)试(Shi)可(Ke)能(Neng)性(Xing)很(Hen)大(Da)啊(A),2011年(Nian)1月(Yue)11日(Ri),J-20首(Shou)飞(Fei),这(Zhe)个(Ge)让(Rang)大(Da)家(Jia)记(Ji)忆(Yi)非(Fei)常(Chang)深(Shen)刻(Ke),因(Yin)此(Ci)每(Mei)年(Nian)的(De)1月(Yue)11日(Ri),军(Jun)迷(Mi)门(Men)都(Du)会(Hui)期(Qi)盼(Pan)新(Xin)的(De)装(Zhuang)备(Bei)出(Chu)现(Xian)在(Zai)大(Da)家(Jia)面(Mian)前(Qian)。接(Jie)下(Xia)来(Lai)还(Huan)有(You)哪(Na)些(Xie)工(Gong)作(Zuo)?系(Xi)泊(Bo)后(Hou)海(Hai)试(Shi)还(Huan)要(Yao)几(Ji)步(Bu)才(Cai)能(Neng)真(Zhen)正(Zheng)入(Ru)役(Yi)?接(Jie)下(Xia)来(Lai)的(De)第(Di)一(Yi)步(Bu)肯(Ken)定(Ding)是(Shi)系(Xi)泊(Bo)试(Shi)验(Yan)了(Liao),这(Zhe)个(Ge)央(Yang)视(Shi)都(Du)已(Yi)经(Jing)公(Gong)开(Kai)了(Liao),“按(An)计(Ji)划(Hua)稳(Wen)步(Bu)推(Tui)进(Jin)系(Xi)泊(Bo)试(Shi)验(Yan)”,这(Zhe)可(Ke)是(Shi)官(Guan)宣(Xuan)的(De)结(Jie)果(Guo),这(Zhe)步(Bu)可(Ke)不(Bu)是(Shi)所(Suo)谓(Wei)的(De)系(Xi)留(Liu)港(Gang)池(Chi),而(Er)是(Shi)有(You)一(Yi)系(Xi)列(Lie)的(De)工(Gong)作(Zuo)要(Yao)做(Zuo):系(Xi)泊(Bo)试(Shi)验(Yan)一(Yi)般(Ban)包(Bao)括(Kuo)测(Ce)试(Shi)主(Zhu)机(Ji)、辅(Fu)机(Ji)、锚(Mao)机(Ji)、舵(Duo)机(Ji)和(He)锅(Guo)炉(Lu)以(Yi)及(Ji)船(Chuan)舶(Bo)其(Qi)他(Ta)机(Ji)电(Dian)设(She)备(Bei)等(Deng)此(Ci)时(Shi)的(De)航(Hang)母(Mu)虽(Sui)然(Ran)是(Shi)停(Ting)在(Zai)水(Shui)面(Mian)上(Shang),但(Dan)操(Cao)作(Zuo)的(De)设(She)备(Bei)可(Ke)就(Jiu)多(Duo)了(Liao),比(Bi)如(Ru)主(Zhu)机(Ji)与(Yu)辅(Fu)机(Ji)会(Hui)启(Qi)动(Dong),此(Ci)时(Shi)最(Zui)大(Da)的(De)动(Dong)静(Jing)就(Jiu)是(Shi)会(Hui)冒(Mao)烟(Yan),与(Yu)俄(E)罗(Luo)斯(Si)库(Ku)兹(Zi)尼(Ni)佐(Zuo)夫(Fu)的(De)冒(Mao)黑(Hei)烟(Yan)形(Xing)象(Xiang)不(Bu)一(Yi)样(Yang),我(Wo)国(Guo)辽(Liao)宁(Ning)舰(Jian)和(He)山(Shan)东(Dong)舰(Jian)排(Pai)烟(Yan)并(Bing)不(Bu)黑(Hei),而(Er)是(Shi)淡(Dan)淡(Dan)的(De)轻(Qing)烟(Yan)。因(Yin)为(Wei)福(Fu)建(Jian)舰(Jian)是(Shi)一(Yi)艘(Sou)常(Chang)规(Gui)动(Dong)力(Li)航(Hang)母(Mu),一(Yi)般(Ban)就(Jiu)是(Shi)使(Shi)用(Yong)重(Zhong)油(You)燃(Ran)烧(Shao)的(De)锅(Guo)炉(Lu),然(Ran)后(Hou)以(Yi)蒸(Zheng)汽(Qi)推(Tui)动(Dong)蒸(Zheng)汽(Qi)轮(Lun)机(Ji)工(Gong)作(Zuo),所(Suo)以(Yi)各(Ge)位(Wei)会(Hui)看(Kan)到(Dao)锅(Guo)炉(Lu)冒(Mao)出(Chu)的(De)烟(Yan)尘(Chen),福(Fu)建(Jian)舰(Jian)在(Zai)港(Gang)池(Chi)内(Nei)舾(Zuo)装(Zhuang)期(Qi)间(Jian)的(De)今(Jin)年(Nian)5月(Yue)底(Di)就(Jiu)已(Yi)经(Jing)冒(Mao)过(Guo)烟(Yan)了(Liao)。2023年(Nian)5月(Yue)底(Di)主(Zhu)机(Ji)试(Shi)车(Che)另(Ling)一(Yi)个(Ge)则(Ze)是(Shi)辅(Fu)机(Ji)开(Kai)机(Ji),福(Fu)建(Jian)舰(Jian)除(Chu)了(Liao)锅(Guo)炉(Lu)外(Wai)还(Huan)有(You)辅(Fu)机(Ji)动(Dong)力(Li),当(Dang)然(Ran)各(Ge)位(Wei)不(Bu)要(Yao)怀(Huai)疑(Yi)是(Shi)锅(Guo)炉(Lu)动(Dong)力(Li)不(Bu)可(Ke)靠(Kao),而(Er)是(Shi)辅(Fu)机(Ji)是(Shi)航(Hang)母(Mu)必(Bi)备(Bei)的(De)设(She)施(Shi),比(Bi)如(Ru)美(Mei)国(Guo)海(Hai)军(Jun)的(De)福(Fu)特(Te)级(Ji)电(Dian)磁(Ci)弹(Dan)射(She)核(He)动(Dong)力(Li)航(Hang)母(Mu),至(Zhi)少(Shao)有(You)8台(Tai)辅(Fu)助(Zhu)柴(Chai)油(You)机(Ji)作(Zuo)为(Wei)动(Dong)力(Li),并(Bing)且(Qie)在(Zai)后(Hou)续(Xu)建(Jian)造(Zao)的(De)CVN80和(He)CVN81两(Liang)艘(Sou)舰(Jian)上(Shang)又(You)增(Zeng)加(Jia)了(Liao)2台(Tai)柴(Chai)油(You)机(Ji)组(Zu)。这(Zhe)些(Xie)柴(Chai)油(You)机(Ji)作(Zuo)为(Wei)航(Hang)母(Mu)失(Shi)去(Qu)动(Dong)力(Li)后(Hou)的(De)应(Ying)急(Ji)动(Dong)力(Li),也(Ye)可(Ke)能(Neng)作(Zuo)为(Wei)应(Ying)急(Ji)发(Fa)电(Dian)机(Ji)动(Dong)力(Li)电(Dian)源(Yuan)的(De)角(Jiao)色(Se)出(Chu)现(Xian),我(Wo)国(Guo)的(De)003航(Hang)母(Mu)福(Fu)建(Jian)舰(Jian)的(De)辅(Fu)助(Zhu)动(Dong)力(Li)则(Ze)更(Geng)重(Zhong)要(Yao),极(Ji)有(You)可(Ke)能(Neng)作(Zuo)为(Wei)电(Dian)磁(Ci)弹(Dan)射(She)储(Chu)能(Neng)设(She)施(Shi)的(De)发(Fa)电(Dian)机(Ji)动(Dong)力(Li)出(Chu)现(Xian),笔(Bi)者(Zhe)曾(Zeng)计(Ji)算(Suan)过(Guo),要(Yao)完(Wan)成(Cheng)福(Fu)建(Jian)舰(Jian)战(Zhan)斗(Dou)机(Ji)弹(Dan)射(She)起(Qi)飞(Fei)任(Ren)务(Wu),需(Xu)要(Yao)三(San)台(Tai)QC-185燃(Ran)气(Qi)轮(Lun)机(Ji)作(Zuo)为(Wei)动(Dong)力(Li),这(Zhe)种(Zhong)发(Fa)电(Dian)设(She)施(Shi)在(Zai)系(Xi)泊(Bo)试(Shi)验(Yan)时(Shi)肯(Ken)定(Ding)会(Hui)进(Jin)行(Xing)测(Ce)试(Shi)。燃(Ran)气(Qi)轮(Lun)机(Ji)的(De)测(Ce)试(Shi)要(Yao)比(Bi)锅(Guo)炉(Lu)烟(Yan)尘(Chen)要(Yao)小(Xiao)多(Duo)了(Liao),估(Gu)计(Ji)很(Hen)难(Nan)分(Fen)辨(Bian)出(Chu)来(Lai)!锚(Mao)机(Ji)的(De)测(Ce)试(Shi)应(Ying)该(Gai)是(Shi)能(Neng)看(Kan)到(Dao)的(De)、舵(Duo)机(Ji)就(Jiu)看(Kan)不(Bu)到(Dao)了(Liao),正(Zheng)常(Chang)应(Ying)该(Gai)在(Zai)水(Shui)下(Xia)动(Dong)作(Zuo),船(Chuan)舶(Bo)其(Qi)他(Ta)机(Ji)电(Dian)设(She)备(Bei)估(Gu)计(Ji)也(Ye)看(Kan)不(Bu)到(Dao),早(Zao)期(Qi)雷(Lei)达(Da)都(Du)是(Shi)转(Zhuan)动(Dong)的(De),现(Xian)在(Zai)的(De)相(Xiang)控(Kong)阵(Zhen)雷(Lei)达(Da)都(Du)不(Bu)动(Dong)了(Liao),从(Cong)外(Wai)观(Guan)上(Shang)看(Kan)根(Gen)本(Ben)就(Jiu)不(Bu)知(Zhi)道(Dao)它(Ta)是(Shi)不(Bu)是(Shi)在(Zai)工(Gong)作(Zuo),不(Bu)过(Guo)有(You)一(Yi)点(Dian)可(Ke)以(Yi)肯(Ken)定(Ding),系(Xi)泊(Bo)测(Ce)试(Shi)的(De)夜(Ye)间(Jian),舰(Jian)岛(Dao)上(Shang)一(Yi)定(Ding)会(Hui)有(You)灯(Deng)光(Guang),甲(Jia)板(Ban)上(Shang)一(Yi)定(Ding)会(Hui)有(You)指(Zhi)示(Shi)灯(Deng)。除(Chu)了(Liao)常(Chang)规(Gui)的(De)试(Shi)验(Yan)外(Wai),还(Huan)包(Bao)括(Kuo)一(Yi)些(Xie)附(Fu)属(Shu)设(She)施(Shi):救(Jiu)生(Sheng)设(She)备(Bei)、舷(Xian)梯(Ti)试(Shi)验(Yan),门(Men)窗(Chuang)舱(Cang)口(Kou)盖(Gai)试(Shi)验(Yan)、信(Xin)号(Hao)设(She)备(Bei)试(Shi)验(Yan)、灭(Mie)火(Huo)试(Shi)验(Yan)、排(Pai)水(Shui)试(Shi)验(Yan)、通(Tong)风(Feng)试(Shi)验(Yan)以(Yi)及(Ji)配(Pei)电(Dian)系(Xi)统(Tong)试(Shi)验(Yan)等(Deng)等(Deng)。系(Xi)泊(Bo)后(Hou)的(De)航(Hang)母(Mu)还(Huan)要(Yao)进(Jin)行(Xing)哪(Na)些(Xie)操(Cao)作(Zuo)才(Cai)能(Neng)入(Ru)役(Yi)?系(Xi)泊(Bo)测(Ce)试(Shi)是(Shi)“海(Hai)试(Shi)”前(Qian)的(De)“开(Kai)胃(Wei)菜(Cai)”,正(Zheng)餐(Can)的(De)量(Liang)可(Ke)不(Bu)少(Shao),因(Yin)为(Wei)航(Hang)母(Mu)几(Ji)乎(Hu)相(Xiang)当(Dang)于(Yu)一(Yi)个(Ge)移(Yi)动(Dong)的(De)机(Ji)场(Chang),包(Bao)括(Kuo)航(Hang)行(Xing)系(Xi)统(Tong)、航(Hang)空(Kong)系(Xi)统(Tong)、电(Dian)子(Zi)系(Xi)统(Tong)、武(Wu)器(Qi)系(Xi)统(Tong)、动(Dong)力(Li)等(Deng)多(Duo)个(Ge)子(Zi)系(Xi)统(Tong),需(Xu)要(Yao)安(An)排(Pai)多(Duo)次(Ci)海(Hai)试(Shi)测(Ce)试(Shi)不(Bu)同(Tong)的(De)系(Xi)统(Tong),总(Zong)时(Shi)间(Jian)可(Ke)能(Neng)会(Hui)长(Chang)达(Da)1~2年(Nian)甚(Shen)至(Zhi)更(Geng)久(Jiu),比(Bi)如(Ru)法(Fa)国(Guo)的(De)“戴(Dai)高(Gao)乐(Le)”号(Hao)核(He)动(Dong)力(Li)航(Hang)母(Mu)的(De)海(Hai)试(Shi)时(Shi)间(Jian)是(Shi)4年(Nian)。海(Hai)试(Shi)主(Zhu)要(Yao)分(Fen)为(Wei)两(Liang)大(Da)流(Liu)程(Cheng):厂(Chang)家(Jia)海(Hai)上(Shang)测(Ce)试(Shi):验(Yan)证(Zheng)舰(Jian)艇(Ting)的(De)动(Dong)力(Li)、机(Ji)械(Xie)电(Dian)气(Qi)设(She)备(Bei)以(Yi)及(Ji)各(Ge)型(Xing)武(Wu)器(Qi)系(Xi)统(Tong)是(Shi)否(Fou)符(Fu)合(He)设(She)计(Ji)要(Yao)求(Qiu)。海(Hai)军(Jun)海(Hai)上(Shang)验(Yan)收(Shou)测(Ce)试(Shi):包(Bao)括(Kuo)航(Hang)母(Mu)的(De)机(Ji)械(Xie)性(Xing)能(Neng)和(He)指(Zhi)挥(Hui)通(Tong)信(Xin)、侦(Zhen)察(Cha)探(Tan)测(Ce)、火(Huo)力(Li)武(Wu)器(Qi)、航(Hang)空(Kong)系(Xi)统(Tong)、舰(Jian)面(Mian)系(Xi)统(Tong)、航(Hang)行(Xing)设(She)备(Bei)、系(Xi)统(Tong)测(Ce)试(Shi)、动(Dong)力(Li)装(Zhuang)置(Zhi)测(Ce)试(Shi)和(He)满(Man)功(Gong)率(Lv)航(Hang)行(Xing)转(Zhuan)向(Xiang)及(Ji)倒(Dao)车(Che)测(Ce)试(Shi)、航(Hang)行(Xing)设(She)备(Bei)和(He)系(Xi)统(Tong)测(Ce)试(Shi)、动(Dong)力(Li)装(Zhuang)置(Zhi)测(Ce)试(Shi)和(He)满(Man)功(Gong)率(Lv)航(Hang)行(Xing)及(Ji)倒(Dao)车(Che)测(Ce)试(Shi)、损(Sun)管(Guan)和(He)消(Xiao)防(Fang)及(Ji)救(Jiu)生(Sheng)系(Xi)统(Tong)的(De)试(Shi)验(Yan)。各(Ge)位(Wei)关(Guan)注(Zhu)的(De)电(Dian)磁(Ci)弹(Dan)射(She)测(Ce)试(Shi)将(Jiang)会(Hui)在(Zai)海(Hai)军(Jun)海(Hai)上(Shang)验(Yan)收(Shou)测(Ce)试(Shi)里(Li)进(Jin)行(Xing),这(Zhe)个(Ge)将(Jiang)会(Hui)测(Ce)试(Shi)从(Cong)轻(Qing)载(Zai)弹(Dan)射(She)到(Dao)满(Man)弹(Dan)满(Man)油(You)弹(Dan)射(She)试(Shi)验(Yan)等(Deng),当(Dang)然(Ran)也(Ye)会(Hui)测(Ce)试(Shi)电(Dian)磁(Ci)拦(Lan)阻(Zu),航(Hang)母(Mu)必(Bi)须(Xu)做(Zuo)到(Dao)弹(Dan)得(De)出(Chu)去(Qu),也(Ye)要(Yao)能(Neng)收(Shou)得(De)回(Hui)来(Lai),对(Dui)于(Yu)航(Hang)母(Mu)这(Zhe)种(Zhong)总(Zong)长(Chang)度(Du)才(Cai)300多(Duo)米(Mi),着(Zhuo)陆(Lu)区(Qu)长(Chang)度(Du)不(Bu)超(Chao)过(Guo)250米(Mi)的(De)航(Hang)母(Mu)来(Lai)说(Shuo),必(Bi)须(Xu)要(Yao)拦(Lan)阻(Zu)索(Suo)才(Cai)能(Neng)拦(Lan)住(Zhu),并(Bing)且(Qie)战(Zhan)斗(Dou)机(Ji)几(Ji)乎(Hu)是(Shi)开(Kai)着(Zhuo)发(Fa)动(Dong)机(Ji)全(Quan)功(Gong)率(Lv)“拍(Pai)”落(Luo)在(Zai)甲(Jia)板(Ban)上(Shang)的(De),拦(Lan)阻(Zu)的(De)难(Nan)度(Du)是(Shi)比(Bi)较(Jiao)高(Gao)的(De),和(He)弹(Dan)射(She)系(Xi)统(Tong)是(Shi)一(Yi)样(Yang)重(Zhong)要(Yao)。F/A-18尾(Wei)钩(Gou)挂(Gua)住(Zhu)拦(Lan)阻(Zu)索(Suo)这(Zhe)些(Xie)工(Gong)作(Zuo)都(Du)完(Wan)成(Cheng)后(Hou),航(Hang)母(Mu)就(Jiu)基(Ji)本(Ben)通(Tong)过(Guo)了(Liao)“验(Yan)收(Shou)”,接(Jie)下(Xia)来(Lai)就(Jiu)是(Shi)海(Hai)军(Jun)接(Jie)收(Shou)航(Hang)母(Mu)后(Hou)训(Xun)练(Lian)以(Yi)及(Ji)形(Xing)成(Cheng)战(Zhan)斗(Dou)力(Li)的(De)过(Guo)程(Cheng)了(Liao),之(Zhi)后(Hou)会(Hui)选(Xuan)个(Ge)良(Liang)辰(Chen)吉(Ji)日(Ri)正(Zheng)式(Shi)入(Ru)役(Yi)。三(San)条(Tiao)弹(Dan)射(She)器(Qi)亮(Liang)了(Liao)!为(Wei)何(He)白(Bai)晃(Huang)晃(Huang),亮(Liang)瞎(Xia)大(Da)家(Jia)的(De)双(Shuang)眼(Yan)?这(Zhe)次(Ci)“海(Hai)试(Shi)”画(Hua)面(Mian)留(Liu)给(Gei)大(Da)家(Jia)最(Zui)大(Da)印(Yin)象(Xiang)应(Ying)该(Gai)就(Jiu)是(Shi)三(San)条(Tiao)电(Dian)磁(Ci)弹(Dan)射(She)器(Qi)了(Liao),那(Na)个(Ge)亮(Liang)白(Bai)色(Se)的(De)“装(Zhuang)饰(Shi)”真(Zhen)是(Shi)让(Rang)人(Ren)眼(Yan)前(Qian)一(Yi)亮(Liang),不(Bu)过(Guo)各(Ge)位(Wei)别(Bie)误(Wu)会(Hui)了(Liao),这(Zhe)并(Bing)不(Bu)止(Zhi)真(Zhen)正(Zheng)的(De)弹(Dan)射(She)器(Qi),而(Er)是(Shi)处(Chu)在(Zai)“养(Yang)护(Hu)”状(Zhuang)态(Tai)的(De)弹(Dan)射(She)器(Qi),某(Mou)种(Zhong)遮(Zhe)风(Feng)避(Bi)雨(Yu)的(De)装(Zhuang)置(Zhi)将(Jiang)其(Qi)“扣(Kou)”起(Qi)来(Lai)了(Liao),不(Bu)至(Zhi)于(Yu)暴(Bao)露(Lu)在(Zai)外(Wai)被(Bei)风(Feng)吹(Chui)雨(Yu)打(Da)。在(Zai)过(Guo)去(Qu)关(Guan)于(Yu)003航(Hang)母(Mu)的(De)文(Wen)章(Zhang)中(Zhong)笔(Bi)者(Zhe)已(Yi)经(Jing)有(You)过(Guo)很(Hen)多(Duo)次(Ci)对(Dui)电(Dian)磁(Ci)弹(Dan)射(She)器(Qi)的(De)介(Jie)绍(Shao)了(Liao),本(Ben)文(Wen)并(Bing)不(Bu)打(Da)算(Suan)过(Guo)多(Duo)的(De)言(Yan)语(Yu)描(Miao)述(Shu),这(Zhe)种(Zhong)装(Zhuang)置(Zhi)是(Shi)利(Li)用(Yong)重(Zhong)接(Jie)线(Xian)圈(Quan)发(Fa)射(She)原(Yuan)理(Li),在(Zai)储(Chu)能(Neng)设(She)备(Bei)提(Ti)供(Gong)的(De)强(Qiang)大(Da)电(Dian)力(Li)下(Xia)将(Jiang)40吨(Dun)重(Zhong)的(De)重(Zhong)型(Xing)舰(Jian)载(Zai)机(Ji)在(Zai)2-3秒(Miao)加(Jia)速(Su)到(Dao)240千(Qian)米(Mi)/小(Xiao)时(Shi)的(De)起(Qi)飞(Fei)速(Su)度(Du),所(Suo)以(Yi)这(Zhe)种(Zhong)装(Zhuang)置(Zhi)需(Xu)要(Yao)一(Yi)个(Ge)相(Xiang)当(Dang)强(Qiang)大(Da)的(De)储(Chu)能(Neng)设(She)备(Bei)以(Yi)及(Ji)充(Chong)电(Dian)系(Xi)统(Tong)。有(You)兴(Xing)趣(Qu)的(De)各(Ge)位(Wei)可(Ke)以(Yi)翻(Fan)下(Xia)笔(Bi)者(Zhe)过(Guo)去(Qu)的(De)文(Wen)章(Zhang),本(Ben)文(Wen)就(Jiu)不(Bu)啰()嗦(Zuo)了(Liao),下(Xia)面(Mian)简(Jian)单(Dan)介(Jie)绍(Shao)下(Xia)电(Dian)磁(Ci)拦(Lan)阻(Zu)的(De)实(Shi)现(Xian),此(Ci)前(Qian)在(Zai)文(Wen)章(Zhang)中(Zhong)有(You)过(Guo)介(Jie)绍(Shao),但(Dan)并(Bing)不(Bu)是(Shi)特(Te)别(Bie)详(Xiang)细(Xi),下(Xia)文(Wen)将(Jiang)以(Yi)美(Mei)军(Jun)福(Fu)特(Te)号(Hao)航(Hang)母(Mu)电(Dian)磁(Ci)拦(Lan)阻(Zu)为(Wei)例(Li)简(Jian)单(Dan)说(Shuo)说(Shuo)电(Dian)磁(Ci)拦(Lan)阻(Zu)是(Shi)怎(Zen)么(Me)实(Shi)现(Xian)的(De)。液(Ye)压(Ya)拦(Lan)阻(Zu)与(Yu)电(Dian)磁(Ci)拦(Lan)阻(Zu)上(Shang)文(Wen)已(Yi)经(Jing)说(Shuo)了(Liao),拦(Lan)阻(Zu)要(Yao)在(Zai)与(Yu)起(Qi)飞(Fei)差(Cha)不(Bu)多(Duo)的(De)时(Shi)间(Jian)(2.5~3秒(Miao))内(Nei)将(Jiang)一(Yi)架(Jia)战(Zhan)斗(Dou)机(Ji)从(Cong)244千(Qian)米(Mi)/小(Xiao)时(Shi)将(Jiang)到(Dao)零(Ling),这(Zhe)就(Jiu)是(Shi)拦(Lan)阻(Zu)设(She)备(Bei)要(Yao)做(Zuo)的(De)事(Shi)情(Qing),无(Wu)论(Lun)是(Shi)液(Ye)压(Ya)还(Huan)是(Shi)电(Dian)磁(Ci)拦(Lan)阻(Zu)结(Jie)果(Guo)都(Du)一(Yi)样(Yang),但(Dan)过(Guo)程(Cheng)可(Ke)能(Neng)就(Jiu)有(You)很(Hen)大(Da)的(De)差(Cha)别(Bie)了(Liao)。上(Shang)图(Tu)是(Shi)液(Ye)压(Ya)拦(Lan)阻(Zu)系(Xi)统(Tong)的(De)组(Zu)成(Cheng)部(Bu)分(Fen),都(Du)是(Shi)液(Ye)压(Ya)缸(Gang)以(Yi)及(Ji)缓(Huan)冲(Chong)池(Chi),看(Kan)起(Qi)来(Lai)难(Nan)度(Du)应(Ying)该(Gai)也(Ye)不(Bu)高(Gao),如(Ru)果(Guo)是(Shi)慢(Man)慢(Man)减(Jian)速(Su)的(De)话(Hua),但(Dan)战(Zhan)斗(Dou)机(Ji)拦(Lan)阻(Zu)是(Shi)在(Zai)2~3秒(Miao)内(Nei)将(Jiang)244千(Qian)米(Mi)/小(Xiao)时(Shi)的(De)速(Su)度(Du)减(Jian)至(Zhi)零(Ling),大(Da)约(Yue)相(Xiang)当(Dang)于(Yu)8.978e+7焦(Jiao)耳(Er)的(De)能(Neng)量(Liang),相(Xiang)当(Dang)于(Yu)25度(Du)电(Dian),可(Ke)以(Yi)烧(Shao)开(Kai)大(Da)约(Yue)75千(Qian)克(Ke)水(Shui),所(Suo)以(Yi)这(Zhe)些(Xie)液(Ye)压(Ya)油(You)缸(Gang)的(De)油(You)温(Wen)升(Sheng)会(Hui)相(Xiang)当(Dang)高(Gao),因(Yin)此(Ci)需(Xu)要(Yao)一(Yi)个(Ge)散(San)热(Re)器(Qi)将(Jiang)其(Qi)散(San)热(Re),或(Huo)者(Zhe)用(Yong)一(Yi)个(Ge)大(Da)的(De)液(Ye)压(Ya)油(You)缸(Gang)为(Wei)其(Qi)“蓄(Xu)热(Re)”。当(Dang)然(Ran)这(Zhe)只(Zhi)是(Shi)一(Yi)架(Jia)战(Zhan)斗(Dou)机(Ji)的(De)拦(Lan)阻(Zu)散(San)热(Re)能(Neng)量(Liang),如(Ru)果(Guo)是(Shi)多(Duo)架(Jia)战(Zhan)斗(Dou)机(Ji)的(De)话(Hua),需(Xu)要(Yao)一(Yi)个(Ge)相(Xiang)当(Dang)大(Da)的(De)液(Ye)压(Ya)油(You)储(Chu)存(Cun)池(Chi)来(Lai)保(Bao)持(Chi)足(Zu)够(Gou)的(De)热(Re)容(Rong)量(Liang),否(Fou)则(Ze)这(Zhe)液(Ye)压(Ya)油(You)也(Ye)要(Yao)“烧(Shao)开(Kai)”了(Liao)。另(Ling)一(Yi)个(Ge)问(Wen)题(Ti)则(Ze)是(Shi)液(Ye)压(Ya)拦(Lan)阻(Zu)的(De)液(Ye)力(Li)调(Diao)节(Jie)不(Bu)太(Tai)容(Rong)易(Yi),就(Jiu)是(Shi)拦(Lan)阻(Zu)减(Jian)速(Su)过(Guo)载(Zai)比(Bi)较(Jiao)高(Gao)。电(Dian)磁(Ci)拦(Lan)阻(Zu)与(Yu)液(Ye)压(Ya)拦(Lan)阻(Zu)差(Cha)别(Bie)比(Bi)较(Jiao)大(Da),以(Yi)福(Fu)特(Te)号(Hao)电(Dian)磁(Ci)弹(Dan)射(She)航(Hang)母(Mu)的(De)AAG(先(Xian)进(Jin)电(Dian)磁(Ci)拦(Lan)阻(Zu)系(Xi)统(Tong))为(Wei)例(Li),主(Zhu)要(Yao)使(Shi)用(Yong)水(Shui)力(Li)液(Ye)力(Li)阻(Zu)尼(Ni)装(Zhuang)置(Zhi)以(Yi)及(Ji)机(Ji)械(Xie)阻(Zu)尼(Ni)+电(Dian)机(Ji)调(Diao)节(Jie),完(Wan)成(Cheng)拦(Lan)电(Dian)磁(Ci)拦(Lan)阻(Zu)的(De)过(Guo)程(Cheng),简(Jian)单(Dan)结(Jie)构(Gou)图(Tu)如(Ru)下(Xia):上(Shang)图(Tu)中(Zhong)的(De)各(Ge)个(Ge)设(She)备(Bei)笔(Bi)者(Zhe)已(Yi)经(Jing)标(Biao)注(Zhu)了(Liao),应(Ying)该(Gai)比(Bi)较(Jiao)容(Rong)易(Yi)理(Li)解(Jie),甲(Jia)板(Ban)上(Shang)降(Jiang)落(Luo)的(De)战(Zhan)斗(Dou)机(Ji)尾(Wei)钩(Gou)挂(Gua)住(Zhu)拦(Lan)阻(Zu)索(Suo),拉(La)动(Dong)经(Jing)过(Guo)一(Yi)组(Zu)动(Dong)滑(Hua)轮(Lun)(增(Zeng)加(Jia)牵(Qian)引(Yin)力(Li)矩(Ju))后(Hou)带(Dai)动(Dong)水(Shui)力(Li)涡(Wo)轮(Lun),消(Xiao)耗(Hao)更(Geng)大(Da)的(De)能(Neng)量(Liang),再(Zai)带(Dai)动(Dong)一(Yi)组(Zu)锥(Zhui)形(Xing)鼓(Gu)轮(Lun),从(Cong)小(Xiao)到(Dao)大(Da),初(Chu)期(Qi)转(Zhuan)速(Su)高(Gao),过(Guo)载(Zai)小(Xiao),后(Hou)期(Qi)转(Zhuan)速(Su)低(Di)扭(Niu)矩(Ju)大(Da),此(Ci)时(Shi)过(Guo)载(Zai)已(Yi)经(Jing)降(Jiang)到(Dao)一(Yi)定(Ding),整(Zheng)个(Ge)减(Jian)速(Su)比(Bi)较(Jiao)柔(Rou)和(He),这(Zhe)个(Ge)鼓(Gu)轮(Lun)的(De)速(Su)度(Du)调(Diao)节(Jie)由(You)末(Mo)端(Duan)的(De)感(Gan)应(Ying)电(Dian)机(Ji)调(Diao)节(Jie),整(Zheng)个(Ge)减(Jian)速(Su)过(Guo)程(Cheng)与(Yu)液(Ye)压(Ya)拦(Lan)阻(Zu)相(Xiang)比(Bi),不(Bu)仅(Jin)可(Ke)控(Kong)并(Bing)且(Qie)过(Guo)载(Zai)也(Ye)降(Jiang)低(Di)了(Liao),飞(Fei)行(Xing)员(Yuan)着(Zhuo)舰(Jian)体(Ti)验(Yan)要(Yao)更(Geng)高(Gao)。不(Bu)过(Guo)福(Fu)特(Te)号(Hao)的(De)这(Zhe)套(Tao)AAG问(Wen)题(Ti)却(Que)不(Bu)小(Xiao),早(Zao)期(Qi)测(Ce)试(Shi)时(Shi)就(Jiu)发(Fa)现(Xian)水(Shui)力(Li)涡(Wo)轮(Lun)叶(Ye)片(Pian)强(Qiang)度(Du)不(Bu)足(Zu)发(Fa)生(Sheng)了(Liao)断(Duan)裂(Lie),经(Jing)过(Guo)2年(Nian)改(Gai)进(Jin)终(Zhong)于(Yu)解(Jie)决(Jue)了(Liao)问(Wen)题(Ti),但(Dan)整(Zheng)体(Ti)可(Ke)靠(Kao)性(Xing)依(Yi)然(Ran)很(Hen)低(Di),据(Ju)资(Zi)料(Liao),AAG先(Xian)进(Jin)拦(Lan)阻(Zu)系(Xi)统(Tong)的(De)无(Wu)故(Gu)障(Zhang)拦(Lan)阻(Zu)次(Ci)数(Shu)仅(Jin)为(Wei)25次(Ci),而(Er)海(Hai)军(Jun)的(De)设(She)计(Ji)要(Yao)求(Qiu)是(Shi)16500次(Ci),两(Liang)者(Zhe)相(Xiang)差(Cha)660倍(Bei)。目(Mu)前(Qian)还(Huan)不(Bu)知(Zhi)道(Dao)003航(Hang)母(Mu)福(Fu)建(Jian)号(Hao)的(De)电(Dian)磁(Ci)拦(Lan)阻(Zu)是(Shi)什(Shi)么(Me)样(Yang)的(De)结(Jie)构(Gou),据(Ju)公(Gong)开(Kai)资(Zi)料(Liao)称(Cheng),福(Fu)建(Jian)号(Hao)无(Wu)论(Lun)在(Zai)电(Dian)磁(Ci)弹(Dan)射(She)还(Huan)是(Shi)电(Dian)磁(Ci)拦(Lan)阻(Zu)上(Shang)都(Du)要(Yao)比(Bi)福(Fu)特(Te)级(Ji)航(Hang)母(Mu)的(De)同(Tong)类(Lei)装(Zhuang)备(Bei)要(Yao)先(Xian)进(Jin)的(De)多(Duo)!另(Ling)外(Wai)关(Guan)于(Yu)这(Zhe)个(Ge)争(Zheng)论(Lun)应(Ying)该(Gai)很(Hen)快(Kuai)就(Jiu)会(Hui)有(You)结(Jie)果(Guo)了(Liao),随(Sui)着(Zhuo)003航(Hang)母(Mu)的(De)海(Hai)试(Shi),各(Ge)项(Xiang)子(Zi)系(Xi)统(Tong)的(De)可(Ke)靠(Kao)性(Xing)究(Jiu)竟(Jing)几(Ji)何(He)会(Hui)逐(Zhu)步(Bu)被(Bei)外(Wai)界(Jie)了(Liao)解(Jie),请(Qing)大(Da)家(Jia)拭(Shi)目(Mu)以(Yi)待(Dai)吧(Ba)。

谤耻驳耻辞测辞苍驳锄丑别测补苍驳诲别迟补颈诲耻,辩耻尘颈补苍诲耻颈辫辞虫颈驳耻补苍虫颈诲别丑耻补,办别苍诲颈苍驳产耻驳耻补苍锄补颈丑补辞诲别谤别苍,诲耻苍别苍驳迟颈补辞肠丑耻濒补颈尘补辞产颈苍驳,诲补苍产颈苍驳产耻蝉丑颈驳辞苍驳辫辞锄丑别苍诲别锄耻辞诲别产耻丑补辞,别谤蝉丑颈锄颈箩颈诲别虫颈苍迟补颈产耻诲耻颈。迟补苍箩颈蝉丑耻补苍驳蹿补苍驳丑别锄耻辞诲别辩颈蝉丑颈,辩耻箩颈虫颈补辞箩颈补苍驳诲耻颈箩颈锄丑别产颈补辞蝉丑颈,箩颈尘别苍驳础滨虫耻测补辞测颈办耻补苍蝉丑颈辫颈苍锄耻辞辫颈苍锄丑补苍虫颈补苍箩颈蝉丑耻,产辞苍补虫耻测补辞测颈办耻补苍肠丑补苍辫颈苍迟颈驳辞苍驳础滨箩颈蝉丑耻锄丑颈肠丑颈。2023苍颈补苍产辞苍补辩耻别诲颈苍驳迟辞苍驳驳耻辞础滨箩颈蝉丑耻濒补颈锄丑颈锄耻辞驳补颈箩耻箩颈,2024苍颈补苍辩耻别诲颈苍驳濒颈补辞测耻箩颈尘别苍驳础滨诲别丑别锄耻辞。

空(碍辞苍驳)间(闯颈补苍)一(驰颈)隅(驰耻),上(厂丑补苍驳)海(贬补颈)久(闯颈耻)事(厂丑颈)申(厂丑别苍)花(贬耻补)足(窜耻)球(蚕颈耻)俱(闯耻)乐(尝别)部(叠耻)的(顿别)官(骋耻补苍)方(贵补苍驳)周(窜丑辞耻)边(叠颈补苍)吸(齿颈)引(驰颈苍)诸(窜丑耻)多(顿耻辞)球(蚕颈耻)迷(惭颈)前(蚕颈补苍)来(尝补颈)。工(骋辞苍驳)作(窜耻辞)人(搁别苍)员(驰耻补苍)介(闯颈别)绍(厂丑补辞),快(碍耻补颈)闪(厂丑补苍)活(贬耻辞)动(顿辞苍驳)期(蚕颈)间(闯颈补苍),该(骋补颈)区(蚕耻)域(驰耻)将(闯颈补苍驳)限(齿颈补苍)量(尝颈补苍驳)售(厂丑辞耻)卖(惭补颈)官(骋耻补苍)方(贵补苍驳)球(蚕颈耻)衣(驰颈)、文(奥别苍)创(颁丑耻补苍驳)等(顿别苍驳)周(窜丑辞耻)边(叠颈补苍),并(叠颈苍驳)将(闯颈补苍驳)定(顿颈苍驳)期(蚕颈)更(骋别苍驳)新(齿颈苍)周(窜丑辞耻)边(叠颈补苍)品(笔颈苍)类(尝别颈)。

门票标出了上千元的高价。巧真大妈的故事,或许给了我们这样一个启示:幸福不在于外在的条件,而在于内心的满足。朱智勋冲朱智勋介绍冲图片冲作品-猫眼电影韩国美女主播朴妮唛视频全集种子分享

南都讯 记者林敏儿 通讯员陈素红 林晓梅 为丰富社区青少年的暑期生活提供了一个展示自我、发挥创意的平台 7 月9 日下午梧桐山社区党委、社区党群服务中心、社区新时代文明实践站、梧桐小学、梧桐小学家委会联合开展了一场别开生面的画出快乐 畅想未来社校家美育体验活动此次活动共吸引20位社区青少年参与

发布于:景泰县
声明:该文观点仅代表作者本人,搜狐号系信息发布平台,搜狐仅提供信息存储空间服务。
意见反馈 合作

Copyright ? 2023 Sohu All Rights Reserved

搜狐公司 版权所有