《我插了英语课代表一节课》免费韩剧在线-惊悚片-星空...
永乐二十二年(1424年)十月,新即位的明仁宗大封宗室,距上一次朝廷大封宗室已过去整整二十年,16岁的朱友壎被堂伯封为罗江王,封号来源于成都府辖下的罗江县(今四川德阳市罗江区)。
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《我插了英语课代表一节课》免费韩剧在线-惊悚片-星空...
结合前文来看大连银行踩雷安信信托所涉金额超过44亿元
各种边盖密封垫换新的,都是一汽大众原厂件。他在自己能力范围内,也的确付出了几乎全部。
丑辞耻尘颈补苍肠补颈蹿补虫颈补苍蝉丑颈锄补颈箩颈补辞产颈补苍产颈补苍,别谤测补测补=迟飞辞驰驰测辞耻锄丑别测补苍驳诲别迟辞苍驳蝉丑颈,办别蝉丑颈辩颈锄耻辞诲别“蹿耻蹿别苍”。
体(罢颈)重(窜丑辞苍驳),作(窜耻辞)为(奥别颈)健(闯颈补苍)康(碍补苍驳)的(顿别)晴(蚕颈苍驳)雨(驰耻)表(叠颈补辞),在(窜补颈)这(窜丑别)个(骋别)阶(闯颈别)段(顿耻补苍)尤(驰辞耻)为(奥别颈)值(窜丑颈)得(顿别)关(骋耻补苍)注(窜丑耻)。
danzaiguoneijixunjieduan,qiumimenmeiyoukandaozhouzuo、zhangzhenzuo、humingxuan、zengfanbo、xujiedengrendeshenying,mingdanzhujiansuozhi21ren。huanyanzhi,jihushinianqingqiuyuanzuchengliaoxinyijiezhongguonanlan。linbaliu | WHOdi5banlinbazuzhizhongliufenlei(zhongyingduizhaozuiquanzuishiyong)yuanchuang2023-07-05 20:58·zhongliuzhuankeyisheng2022nianshijieweishengzuzhi(WHO)fabudi5banzaoxueyulinbazuzhizhongliufenlei(WHO-HAEM5)The 5th edition of the WHO Calssification of Haematolymphoid Tumorsyi、suixizengzhihezhongliubaokuokelongxingzaoxue、gusuizengzhixingzhongliu(manxingsuixibaobaixuebing、manxingzhongxinglixibaobaixuebingdeng)、gusuizengshengyichangzhongliu(MDS)、jixingsuixibaixuebing(AML)dengdeng,tongchangguishuxueyeneike。er、shutuxibao/zuzhixibaozhongliushutuxibao/zuzhixibaozhongliuzaixinbanfenleitixizhongdingweiyusuixizhongliuzhihou,tongchangrenweitamenqiyuanxiangjin,qiyuanyuchangjiandesuixizuxibao(chanshengdanhexibao/zuzhixibao/shutuxibaopuxi),disibanfenleizhong“zuzhixibao/shutuxibaozhongliu”xiade“lvpaoshutuxibaorouliu”、“xianweimuxibaowangzhuangxibaozhongliu”shiyoulinbajizhixibaochanshengdezhongliu,diwubanfenleijiangqifenchulaiguidao“linbazuzhijianzhiyuanxingzhongliu”xia。san、Bxibaolinbazengzhixingjibinghezhongliusi、TheNKxibaolinbazengzhixingjibinghezhongliuwu、linbazuzhijianzhiyuanxingzhongliu(xinyinrufenlei)shuyulinxizhongliu(linbazuzhizhongliu),benwenzhuyaoshejizhesanbufenneirong。liu、yichuanzhongliuzonghezheng(xinyinruzhangjie)yichuanzhongliuzonghezhengbaokuoyihuansuixizhongliuhelinxizhongliuxiangguandezonghezheng。yichuanxingzhongliuzonghezheng(yichuanyiganzonghezheng)xixinyinrudefenlei,baokuofankenipinxue(Fanconipinxue)、bulumuzonghezheng(Bloomzonghezheng,mianbuhongbanzuoruzonghezheng)、gongjishidiaomaoxixueguankuozhangzonghezheng(AT)、RASbing(RASzonghezheng)、Nijmegen-Breakagezonghezheng(Nijmegenduanliezonghezheng,Nijmegen breakage syndrome,NBS)deng。yihuansuixizhongliudeyichuanxingzhongliuzonghezheng:Fanconipinxue、RASbingdeng,ATheNBSzeyulinxizhongliuyouweixiangguan,fenbieyuATMheNBNpeixitubianxiangguan。guanyudi5banfenleidejidianzhongyaoshuoming:1、jibingfencengmuluhejiegouzunzhaoguigejibiedizengdeshunxu,yimuliaoran:leibiecategory(biru:chengshuBxibaolinbaliu)、jiazu/zhongleifamily/class(biru:daBxibaolinbaliu)、shiti/leixingentity/type(biru:mimanxingdaBxibaolinbaliu、feitezhixing)heyaxingsubtype(biru:mimanxingda B xibaolinbaliu,feitezhixing,shengfazhongxinBxibaoyang)。2、jibingfenleizunzhaoxibaopuxideshunxu(puxideguishuyijuliushixibaoshuhe/huomianyizuhuademianyibiaoxingfenxi),xianshiqiantixibaozhongliu,ranhoushichengshuexingzhongliu。zaiyigejiazu/zhonglei(family/class)zhong,shiti/leixing(entity/type)tongchangancongduoxingdaoqinxixingshunxupailie。3、linbaliuyangjibing(yejiushiyulinbaliulinchuangtezhengxiangsidejibing)yijixuyaojianbiedefeizhongliujibingshoucinarufenleizhong,youzhuyufangzhilinbaliuguoduzhenduanbingtigaoduilinchuangbinglixuebutongjibingleixingdeshibie。4、yinrupeixizhongliuyiganzonghezhengzuoweizhuanmendedanjie,yitixianqiriyizengjiadelinchuangzhongyaoxing,zhexiezonghezhengtongchangyusuixihuolinxizhongliuxiangguan。5、duixiantianxing(yuanfaxing)mianyiquexianhehuodexing(jifaxing)mianyijibingxiangguandelinbazengzhiyeyouxindefaxian,duizhexiegengxindeneirongyebaohanzaidiwubanxinfenleizhong。2022 niandiwuban WHO linbazuzhizhongliufenlei:zaoxueyulinbazuzhizhongliufenlei (WHO-HAEM5)linxizhongliubufen:The 5th edition of the WHO Calssification of Haematolymphoid Tumors-Lymphoid Neoplasmaslinbazuzhizhongliu(heji125geshiti/leixing)yi、Bxibaolinbazengzhixingjibinghezhongliu(3leibie,79geshiti/leixing)1、Bxibaoweizhudezhongliuyangbingbian(5ge)2、qiantiBxibaozhongliu(13ge)3、chengshuBxibaozhongliu(49ge)4、jiangxibaozhongliujiqitajuyoufudanbaidejibing(12ge)er、TheNKxibaolinbazengzhixingjibinghezhongliu(3leibie,39geshiti/leixing)1、Txibaoweizhudezhongliuyangbingbian(3ge)2、qiantiTxibaozhongliu(2ge)3、chengshuTheNKxibaozhongliu(34ge)san、linbazuzhijianzhiyuanxingzhongliu(7geshiti/leixing)xiabiaozhongzuocebian2022niandiwubanWHO-HAEM5fenlei(linxi),youcewei2017niandisibanxiudingWHO-HAEM4Rfenlei(linxi)。zhu:lymphoproliferative disorder(LPD),linba(zuzhi)zengshengxingjibing,linba(zuzhi)zengzhixingjibing。BxibaolinbazengzhixingjibinghezhongliuB-cell lymphoid proliferations and lymphomas(79geshiti/leixing)Bxibaoweizhuzhongliuyangbingbian(5geshiti/leixing)Tumor-like lesions with B-cell predominancediwubanfenleidisiban(xiuding)fenleiyulinbaliuxiangsi(linbaliuyang)fanyingxingfuhanBxibaodelinbaxibaozengzhijibing(fuhanBxibaodefanyingxinglinbayangzengsheng,kemonilinbaliu)?Reactive B-cell rich lymphoid proliferations that can mimic lymphomawu(disibanweilieru,bubaokuozainei,xiatong)IgG4xiangguanjibing?IgG4-related diseasewudanzhongxinCastlemanbing?Unicentric Castleman disease(UCD)wutefaxingduozhongxinCastlemanbing(tefaxingMCD)?Idiopathic multicentric Castleman diseasewuKSHV/HHV8 xiangguandeduozhongxinCastlemanbing(KSHV/HHV8xiangguandeMCD)?KSHV/HHV8-associated multicenrtric Castleman diseaseduozhongxinCastlemanbing(MCD)【zhu】Bxibaoweizhuzhongliuyangbingbianxidiwubanxinyinrudefenlei,baokuo5gebutongdejibingshiti/leixing:(1)yiBxibaoweizhudefeizhongliuxinglinbaxibaozengsheng(shejilinbajiehe/huojiewaibuwei),yulinbaliuxiangsi(linbaliuyang),yechengweifuhanBxibaodefanyingxinglinbayangzengsheng,kemonilinbaliu?。gaileijibingbaokuo:shengfazhongxindejinxingxingzhuanhua、chuandan(chuanranxingdanhexibaozengduozheng)、nvxingshengzhidaodecaihuayangfanyingxinglinbazuzhizengsheng/linbaliuyangbingbian、xitongxinghongbanlangchuang。(2)IgG4xiangguanjibing?:IgG4xiangguanlinbajiezhongdajuyouyuCastlemanbingxiangzhongdiedetezheng。(3)Castlemanbingbaokuosanzhongleixing:danzhongxinCastlemanbing?、tefaxingduozhongxinCastlemanbing?、KSHV/HHV8 xiangguandeduozhongxinCastlemanbing?,tamendelinchuanghebinglixuetezhengbutong。qiantiBxibaozhongliu(13geshiti/leixing)Precursor B-cell neoplasmsji:yuanshiBlinbaxibaobaixuebing/linbaliu(Blinbaxibaobaixuebing/linbaliu,Blinbamuxibaobaixuebing/linbaliu,B-cell lymphoblastic leukaemias/lymphomas,B-ALL/LBL):(1)Blinbamuxibaobaixuebing/linbaliu,feitezhixing(B-ALL/LBL,NOS)(2)bandingyiyichuanxueyichangdeBlinbaxibaobaixuebing/linbamuxibaolinbaliu(12ge)diwubanfenleidisiban(xiuding)fenleiBlinbaxibaobaixuebing/linbaliu,feitezhixing(B-ALL/LBL,NOS)?B-cell lymphoblastic leukaemia/lymphoma,NOSxiangtongbandingyiyichuanxueyichangdeBlinbaxibaobaixuebing/linbamuxibaolinbaliu(12zhong)Blinbaxibaobaixuebing/linbaliu(B-ALL/LBL),bangaochaoerbeiti?B-ALL/LBL with high hyperdiploidyBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),banchaoerbeitiBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),banyaerbeiti(dierbeiti)?B-ALL/LBL with hypodiploidyxiangtongBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),baniAMP21?B-ALL/LBL with iAMP21xiangtongBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban BCR::ABL1 ronghe?B-ALL/LBL with BCR::ABL1 fusionBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL)bant(9;22)(q34;q11.2); BCR-ABL1rongheBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban BCR::ABL1 yangtezheng?B-ALL/LBL with BCR::ABL1-like featuresBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL), banBCR-ABL1 yangBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban KMT2A zhongpai?B-ALL/LBL with KMT2A rearrangementBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban t(v;11q23.3); KMT2AzhongpaiBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban ETV6::RUNX1 ronghe?B-ALL/LBL with ETV6::RUNX1 fusionBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban t(12;21)(p13.2;q22.1); ETV6-RUNX1rongheBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban ETV6::RUNX1yangtezheng?B-ALL/LBL with ETV6::RUNX1-like featureswuBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban TCF3::PBX1 ronghe?B-ALL/LBL with TCF3::PBX1 fusionBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban t(1;19)(q23;p13.3); TCF3-PBX1rongheBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban IGH::IL3 ronghe?B-ALL/LBL with IGH::IL3 fusionBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban t(5;14)(q31.1;q32.1); IGH/IL3rongheBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),ban TCF3::HLF ronghe?B-ALL/LBL with TCF3::HLF fusionwuBlinbaxibaobaixuebing/linbaliu(B-ALL/LBL),banqitatedingyichuanxueyichang?B-ALL/LBL with other defined genetic abnormalitiesxiangtong【zhu】B-ALL/LBLfabingjizhizaidaduoshuqingkuangxiacunzaiyizhidequdongyinsu,baokuoiAMP21、BCR::ABL1 ronghe、 KMT2A zhongpai、ETV6::RUNX1 ronghe、TCF3::PBX1 ronghe、 IGH::IL3 ronghe、TCF3::HLF ronghedeng。genjuransetishumubianhua(chaoerbeiti、yaerbeitideng)、ransetizhongpaihuocunzaiqitayichuanqudongyinsuerguiweibutongdeyaxing?-?。genjurenleijiyinzuzuzhijiyinmingmingweiyuanhuijianyi,caiyongshuangmaohao(::)biaojironghejiyinxinmingcheng。chucizhiwaijibianjingguoquanmianjianceyerengranwufafenleideyileijibingzeguiweiBlinbaxibaobaixuebing/linbamuxibaolinbaliu,feitezhixing(B-ALL/LBL,NOS)?chengshuBxibaozhongliu(12gejiazu/zhonglei,49geshiti/leixing)Mature B-cell neoplasms(1)zhongliuqianqihezhongliuxingxiaolinbaxibaozengzhi(2ge)(2)piBxibaolinbaliuhebaixuebing(4ge)(3)linbajiangxibaolinbaliu(1ge)(4)bianyuanqulinbaliu(4ge)(5)lvpaoxinglinbaliu(4ge)(6)pifulvpaozhongxinlinbaliu(1ge)(7)taoxibaolinbaliu(3ge)(8)duoxingBxibaolinbaliudezhuanhua(1ge)(9)daBxibaolinbaliu(18ge)(10)bojitelinbaliu(1ge)(11)KSHV/HHV8xiangguanBxibaolinbazengzhixingjibinghelinbaliu(3ge)(12)yumianyiquexianheshidiaoxiangguandelinbazengzhihelinbaliu(5ge)(13)huoqijinlinbaliu(2ge)diwubanfenleidisiban(xiuding)fenleizhongliuqianqihezhongliuxingxiaolinbaxibaozengzhiPre-neoplastic and neoplastic small lymphocytic proliferationsdankelong B linbaxibaozengduozheng(MBL)?Monoclonal B-cell lymphocytosisxiangtongmanxinglinbaxibaobaixuebing/xiaolinbaxibaolinbaliu(CLL/SLL)?Chronic lymphocytic leukaemia/small lymphocytic lymphomaxiangtongB-PLLbingmingbeishanchu(buzaishiweiyigejibingleixing)Bxibaoyoulinbaxibaobaixuebing(B-PLL)B-prolymphocytic leukemiapiBxibaolinbaliuhebaixuebingSplenic B-cell lymphomas and leukaemiasmaoxibaobaixuebing(HCL)?Hairy cell leukaemiaxiangtongpibianyuanqulinbaliu(SMZL)?Splenic marginal zone lymphomaxiangtongpimimanxinghongsuixiaoBxibaolinbaliu(SDRPL)?Splenic diffuse red pulp small B-cell lymphomaxiangtongpiBxibaolinbaliu/baixuebing,banxianzhuheren(SBLPN)?Splenic B-cell lymphoma/leukaemia with prominent nucleoliweibaokuozainei,wucibingming(disibanbingmingshuyuwei:maoxibaobaixuebingbianyixingheCD5yinxingBxibaoyoulinbaxibaobaixuebing)linbajiangxibaolinbaliuLymphoplasmacytic lymphomalinbajiangxibaolinbaliu(LPL)?Lymphoplasmacytic lymphomaxiangtong【zhu】baokuoliangzhongyaxing:IgM-LPL/WM(zuichangjian,yuezhan95%):IgM-LPL/Waldenstromjuqiudanbaixuebing(WM,huashijuqiudanbaixuezheng);feiWMxingLPL(yuezhan5%)。bianyuanqulinbaliuMarginal zone lymphomazhanmoxiangguanlinbazuzhijiewaibianyuanqulinbaliu)(MALT)?Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissuexiangtongyuanfaxingpifubianyuanqulinbaliu(PCMZL)?Primary cutaneous marginal zone lymphomaweidanduliechu(guiruzhanmoxiangguanlinbazuzhijiewaibianyuanqulinbaliu)linbajiebianyuanqulinbaliu(NMZL)?Nodal marginal zone lymphomaxiangtongertong(linbajie)bianyuanqulinbaliu(pNMZL)?Paediatric (nodal) marginal zone lymphomaxiangtong【zhu】jiepobuweibutong,xibaoyichuanxuehejiyintubianpubutong。(1)linbajiebianyuanqulinbaliu(NMZL)hejiewaibianyuanqulinbaliu(EMZL)jiyintubianpubutong。(2)jiewaiMZL(EMZL)changjiandebaokuowei、fei、yanfushuqi、tuoyexian、jiazhuangxian、pifudengbuweideMZL,butongdejiewaiMZLzhijiancunzaixianzhudeyichuanxuechayi。(3)pifuMZLjuyoudutedelinchuangbinglitezheng,qubieyuqitajiewaiMZL(EMZL)erdanliezuoweidulidejibingshitileixing(PCMZL)。(4)ertonglinbajiebianyuanqulinbaliu(pNMZL)shicongNMZLxiadeyigeyaxingshengjichengweiyigedulidejibingshitileixing。lvpaoxinglinbaliuFollicular lymphomayuanweilvpaoxingBxibaozhongliu(ISFN)?In situ follicular B-cell neoplasmyuanweilvpaoxingzhongliu(yuanweilvpaoxingliubian)lvpaoxinglinbaliu(FL)?Follicular lymphomaxiangtongertongxinglvpaoxinglinbaliu?Paediatric-type follicular lymphomaxiangtongshierzhichangxinglvpaoxinglinbaliu?Duodenal-type follicular lymphomaxiangtongpifulvpaozhongxinlinbaliuCutaneous follicle centre lymphomayuanfaxingpifulvpaozhongxinlinbaliu?Primary cutaneous follicle centre lymphomaxiangtongtaoxibaolinbaliuMantle cell lymphomayuanweitaoxibaozhongliu(ISMCN)?In situ mantle cell neoplasmyuanweitaoxibaoliubiantaoxibaolinbaliu(MCL)?Mantle cell lymphomaxiangtongbaixuebingxingfeilinbajiexingtaoxibaolinbaliu(Leukemic non-nodal mantle cell lymphoma,feilinbajieMCL,nnMCL)?xiangtong【zhu】feilinbajieMCL(nnMCL)yuMCLxiangbi,daduomeiyouzhengzhuang,qiyuhouxiangduigenghao,zhuyaoshixueye、gusuihepizangshoulei,henshaohuozhemeiyoulinbajiezhongda。duoxingBxibaolinbaliuzhuanhuaTransformations of indolent B-cell lymphomaduoxingBxibaolinbaliuzhuanhua?Transformations of indolent B-cell lymphomawu【zhu】shoucibaduoxingBxibaolinbaliudegaojibiezhuanhuazuoweiyigedulibufendanlie。daBxibaolinbaliuLarge B-cell lymphomas(LBCL)mimandaBxibaolinbaliu,feitezhixing(NOS)?Diffuse large B-cell lymphoma(DLBCL),NOSxiangtongfuhanTxibao/zuzhixibaodedaBxibaolinbaliu?T-cell/histiocyte-rich large B-cell lymphomaxiangtongmimandaBxibaolinbaliu/gaojibieBxibaolinbaliu,ban MYC he BCL2 zhongpai?DLBCL/HGBL with MYC and BCL2 rearrangementsgaojibieBxibaolinbaliu,ban MYC he BCL2 he/huo BCL6 zhongpaiALKyangxingdaBxibaolinbaliu?ALK-positive large B-cell lymphomaxiangtongdaBxibaolinbaliu,ban IRF4 zhongpai?Lagre B-cell lymphoma with IRF4 rearrangementxiangtonggaojibieBxibaolinbaliu,ban 11q yichang?HGBL with 11q aberrationsBurkittyanglinbaliu,ban 11q yichanglinbaliuyangrouyazhongbing?Lymphomatoid granulomatosisxiangtongEBVyangxingmimandaBxibaolinbaliu?EBV-positive diffuse large B-cell lymphomaEBVyangxingmimandaBxibaolinbaliu,feitezhixing(NOS)mimandaBxibaolinbaliu,banmanxingyanzheng(yumanxingyanzhengxiangguandemimandaBxibaolinbaliu)?Diffuse large B-cell lymphoma associated with chronic inflammationxiangtongxianweidanbai(xianweisu)xiangguandaBxibaolinbaliu?Fibrin-associated large B-cell lymphoma(disibanshiyumanxingyanzhengxiangguandemimandaBxibaolinbaliudeyigeyaxing)tiyeguozaixiangguandaBxibaolinbaliu?Fluid overload-associated large B-cell lymphomawujiangmuxibaolinbaliu?Plasmablastic lymphomaxiangtongyuanfaxingmianyihuomianbuwei(tequanbuwei)daBxibaolinbaliu?Primary large B-cell lymphoma of immune-privileged sites(disibanweidandufenxing,baokuodi4banzhongdeyuanfazhongshushenjingxitong,yuanfaboliti、shiwangmo、zuowandengbuweidemimandaBxibaolinbaliu)yuanfapifumimandaBxibaolinbaliu,tuixing?Primary cutaneous diffuse large B-cell lymphoma,leg typexiangtongxueguanneidaBxibaolinbaliu?Intravascular large B-cell lymphomaxiangtongyuanfazonggedaBxibaolinbaliu?Primary mediastinal large B-cell lymphomaxiangtongzonggehuiqulinbaliu(MGZL)?Mediastinal grey zone lymphomaBxibaolinbaliu,wufafenlei,tezhengjieyuDLBCLhejingdianhuoqijinlinbaliuzhijiangaojibieBxibaolinbaliu,feitezhixing?High-grade B-cell lymphoma(HGBL),NOSxiangtong【zhu】daBxibaolinbaliubaokuoDLBCLfeitezhixingheqita17getedingdaBxibaolinbaliu。(1)DLBCL,NOS?shizuichangjiandeleixing,shiyizuyizhixingdelinbaliu,qixingtai、biaoxingdengjunbumanzumouzhongtedingdaBxibaolinbaliudezhenduanbiaozhun。disibandingyideliangzhongzhuyaoyaxingrengshiyong,jixuqufenGCB/ABC(GCB/feiGCB)yaxing。(2)tiyeguozaixiangguandaBxibaolinbaliu?yeshixinyinrudeleixing,zhuyaobiaoxianweitiqiangshoulei,zuichangjianshixiongmoqiangshoulei,changyoudaozhiyetiguozaidejichujibing(manxingxinshuai、shenshuaijie、ganshuaijie/ganyinghuadeng),duojianyulaonianren,yuhouxiangduijiaohao。yaozhuyi,tayuyuanfaxingshenchuxinglinbaliu(PEL)jiyinbiaodapuheyuhoujunbutong,PELyuhougengcha。PELmuqianguiruKSHV/HHV8xiangguanBxibaolinbazengzhixingjibinghelinbaliuzheyijiazu/zhongleizhong。(3)mianyihuomianbuweideyuanfadaBxibaolinbaliu?yexinbanfenleiyinrudeyigexindezongcheng,shifashengyumianyigongnengzhengchangrenqundeyizuyuanfaqinxixingBxibaolinbaliu,yuanfabuweibaokuozhongshushenjingxitong、bolitishiwangmo、zuowan:yuanfaxingzhongshushenjingxitongDLBCL、yuanfaxingzuowanLBCL、yuanfaxingbolitishiwangmoLBCL。jianglaikenenghuanhuikuochong(biruruxian、pifudeng)。(4)zonggehuiqulinbaliu(MGZL)?juyouyuanfazonggeBxibaolinbaliu(PMBL)hejingdianxinghuoqijinlinbaliu(cHL)dezhongdietezheng,jinfashengyuzongge,shuyudanyishengwuxuetezhengdejibingshiti。BurkittlinbaliuBurkitt lymphomaBurkittlinbaliu(bojitelinbaliu)?Burkitt lymphoma(BL)xiangtong【zhu】bojitelinbaliujiwanggenjuliuxingbingxuebeijinghediliweizhifenweisanzhongliuxingbingxueyaxing:difangxingBL、feidifangxing/sanfaxingBL、mianyiquexianxiangguanBL。kaolvdaoEBVganranzaizaoqifabingjizhizhongqizhongyaozuoyong,jiyufenzitezhengqufenweiliangzhongyaxingqudailiuxingbingxueyaxing,ji:EBVyangxingBLheEBVyinxingBL。KSHV/HHV8xiangguanBxibaolinbazengzhixingjibinghelinbaliuKSHV/HHV8-associated B-cell lymphoid proliferations and lymphomasyuanfaxingshenchuxinglinbaliu(PEL)?Primary effusion lymphomaxiangtongKSHV/HHV8yangxingmimandaBxibaolinbaliu?KSHV/HHV8-positive diffuse large B-cell lymphomaHHV8yangxingmimandaBxibaolinbaliu,feitezhixingKSHV/HHV8yangxingshishengfazhongxinlinbazengzhixingjibing?HSHV/HHV8-positive germinotropic lymphoproliferative disorderHHV8yangxingshishengfazhongxinlinbazengzhixingjibing【zhu】KSHV/HHV8(kaboxirouliuzuozhenbingdu/renleizuozhenbingdu8xing)ganranxiangguandelinbazengzhixingjibingbaokuo:KSHV/HHV8xiangguandeduozhongxinCastlemanbing(KSHV/HHV8-MCD,guidaoBxibaoweizhudezhongliuyangbingbianleibiexia)、yuanfaxingshenchuxinglinbaliu?(Primary effusion lymphoma,PEL)、qiangwaiPEL(EC-PEL)、KSHV/HHV8yangxingmimandaBxibaolinbaliu?(KSHV/HHV8-DLBCL)、KSHV/HHV8yangxingshishengfazhongxinlinbazengzhixingjibing?(KSHV/HHV8-GLPD)。yumianyiquexianheshidiaoxiangguandelinbazengzhihelinbaliuLymphoid proliferations and lymphomas associated with immune deficiency and dysregulationmianyiquexianxiangguanxingsabazuzhizengshengxingjibingmianyiquexian/shidiao(IDD)yinqideguoduzengsheng?Hyperplasias arising in immune deficiency/dysregulationweilieru,disibanbubaokuozainei,disibanbaokuofei(zuzhi)pohuaixingyizhihoulinbazengzhixingjibing(feipohuaixingPTLD)dengmianyiquexian/shidiaoyinqideduoxingxinglinbazengzhi(duoxingxinglinbazuzhizengzhixingjibing)?Polymorphic lymphoproliferative disorders arising in immune deficiency/dysregulationweilieru(disibanbubaokuozainei,baokuoduoxingxingyizhihoulinbazuzhizengzhixingjibing(duoxingxingPTLD)、qitayiyuanxingmianyiquexianxiangguandelinbazuzhizengshengxingjibingdeng)EBVyangxingpifuzhanmokuiyang?EBV-positive mucocutaneous ulcer(EBVMCU)xiangtongmianyiquexian/shidiaoyinqidelinbaliu?Lymphoma arising in immune deficiency/dysregulationweilieru,disibanbubaokuozaineidisibanbaokuodanxingxingyizhihoulinbazuzhizengzhixingjibing(danxingxingPTLD)、jingdianxinghuoqijinlinbaliuyangyizhihoulinbazuzhizengzhixingjibing、HIVganranxiangguanlinbaliudeng)mianyixiangguanlinbayangzengshenghelinbaliudexiantianxingcuowu(xiantianxingmianyiquexianxiangguanlinbazengzhihelinbaliu,mianyichushengcuowuxiangguandelinbazengzhihelinbaliu)?Inborn error of immunity-associated lymphoid proliferations and lymphomaslinbazengzhixingjibingxiangguan,banyuanfamianyijibing(yuyuanfaxingmianyijibing/quexianxiangguandelinbazengzhixingjibing)【zhu】mianyiquexian/shidiao,mianyiquexianbing(immunodeficiency diseases,IDD)shiyizuyouyumianyixitongfayubuquanhuozaoshousunhaisuozhidemianyigongnengquexianyinqidejibing,youerzhongleixing:①yuanfaxingmianyiquexianbing(xiantianxingmianyiquexianbing),yuyichuanyouguan,duofashengzaiyingyouer。②jifaxingmianyiquexianbing(huodexingmianyiquexianbing),kefashengzairenhenianling,duoyinyanzhongganranyouqishizhijieqinfanmianyixitongdeganran、exingzhongliu、yingyongmianyiyizhiji、fangliaohualiaodengyuanyinyinqi。yupeixitubianxiangguandeyuanfaxingmianyiquexianbeiguojimianyixuehuilianhehuizhongxinmingmingwei“mianyichushengcuowu”(inborn error of immunity,IEI)(jiwangchengweixiantianxingmianyiquexian),xinbanWHO-HAEM5fenleicaiyonggaishuyumingcheng。huoqijinlinbaliuHodgkin lymphmajingdianxinghuoqijinlinbaliu?Classic Hodgkin lymphma(cHL)xiangtongjiejiexinglinbaxibaoweizhuxinghuoqijinlinbaliu?Nodular lymphocyte predominant Hodgkin lymphma(NLPHL)xiangtong【zhu】huoqijinlinbaliuzaijiubanzhongzuoweidulideleibie(category),Hodgkinxibao(RSxibaodedanhebianyixing)heReed-Sternbergxibao(lisixibao,RSxibao,biaoxianweiduohejuxibao)qiyuanyushengfazhongxindeBxibao,bingkaolvdaodangdaidezhiliaomoshi,bahuoqijinlinbaliudandufenchulaideyuhouyiyibuda,yincixinbanfenleibahuoqijinlinbaliubeiguidaochengshuBxibaozhongliuleibie(category)xia,zuoweichengshuBxibaozhongliudeyigejiazu/zhonglei(family/class)。linbaxibaoweizhuxinghuoqijinlinbaliu(LPHL),zhanhuoqijinlinbaliu5%-6%,dabufenzaidibeijingxiakejiandaojiejieyangjiegou,beijingweixiaolinbaxibaojujimijichengjiejiefenbu,xiangsiyulvpaolinbaliu,yechengweijiejiexinglinbaxibaoweizhuxingHL(NLPHL)。jinyoujishaoshuzhenduanxingdeRSxibao,qiechangweiyileichengwei“L&H”RSxibao,yechengweiHLdexibaoxibaohe/huozuzhixibaoyaxing,yechengwei“baomihuaxibao”。kefashengzairenhenianling,zhongweifabingnianling60sui,nanxingduojian,changqinfanlinbajie,yuhoujiaohao。mianyizuhuaranseCD30(-),biaodaBxibaokangyuan(CD20+,CD15-)。kehouqifufa,kezhuanhuaweiBxibaoNHL。jingdianxinghuoqijinlinbaliu(CHL),juyouxingtaixuedianxingdezhenduanxingRSxibaojiqidanhebianyixing(huoqijinxibao),liuxibaotezhengxingbiaodaCD30+,changbiaodaCD15+,CE20-。baokuosigeyaxing:jiejieyinghuaxingcHL(NSCHL)、fuyulinbaxibaoxingcHL(LRCHL)、hunhexibaoxingcHL(MCHL)、linbaxibaoxiaojianxingcHL(LDCHL)。jiangxibaozhongliujiqitajuyoufudanbaidejibing(12geshiti/leixing)Plasma cell neoplasms and other diseases with paraproteinsdiwubanfenleidisiban(xiuding)fenleidankelongbingzhongqiudanbaibingMonoclonal gammopathieslengningjisubing(CAD)?Cold agglutinin diseasewuyiyiweimingdeIgMdankelongbingzhongqiudanbaibing?IgM monoclonal gammopathy of undetermined significance(IgM MGUS)xiangtongyiyiweimingdefeiIgMdankelongbingzhongqiudanbaibing?Non-IgM MGUSxiangtongjuyoushenzangyiyidedankelongbingzhongqiudanbaibing?Monoclonal gammopathy of renal significance(MGRS)weilie rudankelongmianyiqiudanbaichenjidejibingDiseases with monoclonal immunoglobulin depositionmianyiqiudanbaixiangguan(AL)dianfenyangbianxing?Immunoglobulin-related(AL) amyloidosisyuanfaxing(qinglian)dianfenyangbianxingdankelongmianyiqiudanbaichenjibing?Monoclonal immunoglobulin deposition diseaseqinglianhezhonglianchenjibingzhonglianbingHeavy chain diseases(HCD)μ(Mu)zhonglianbing?Mu heavy chain diseasexiangtongγ(Gamma)zhonglianbing?Gamma heavy chain diseasexiangtongα(Alpha)zhonglianbing?Alpha heavy chain diseasexiangtongjiangxibaozhongliuPlasma cell neoplasmsjiangxibaoliu?Plasmacytomaxiangtongjiangxibaogusuiliu?Plasma cell myeloma/multiple myelomaxiangtongfuzhongliuzonghezhengxiangguandejiangxibaozhongliu?Plasma cell neoplasms with associated paraneoplastic syndromePOEMS zonghezhengTEMPI zonghezhengAESOP zonghezheng(adenopathy and extensive skin patch overlying a plasmacytoma,linbajiezhongdaheguangfanpifubankuaibanjiangxibaoliu)xiangtong(danAESOP zonghezhengyiqianbubaokuozainei)TheNKxibaolinbazengzhixingjibinghezhongliuT-cell and NK-cell lymphoid proliferations and lymphomas(39geshiti/leixing)Txibaoweizhuzhongliuyangbingbian(3geshiti/leixing)Tumor-like lesions with T-cell predominancediwubanfenleidisiban(xiuding)fenleijuchi-tengbenbing?Kikuchi-Fujimoto disease(KFD)wuduoxing T linbamuxibaoxingzengzhi?Indolent T-lymphoblastic proliferation(ITLP)wuzishenmianyixinglinbazengzhizonghezheng?Autoimmune lymphoproliferative syndrome(ALPS)wu【zhu】Txibaoweizhuzhongliuyangbingbianxidiwubanxinyinrudefenlei。qiantiTxibaozhongliu(2geshiti/leixing)Precursor T-cell neoplasmsji:yuanshiTlinbaxibaobaixuebing/linbaliu(Tlinbaxibaobaixuebing/linbaliu,Tlinbamuxibaobaixuebing/linbaliu,T-lymphoblastic leukaemias/lymphomas,T-ALL/LBL)diwubanfenleidisiban(xiuding)fenleiTlinbamuxibaobaixuebing/linbaliu,feitezhixing?T-lymphoblastic leukaemia/lymphoma,NOS(T-ALL/LBL,NOS)Tlinbamuxibaobaixuebing/linbaliuzaoqiTqiantilinbamuxibaobaixuebing/linbaliu?Early T-precursor ALL/LBL (ETP-ALL/LBL)zaoqiTqiantilinbaxibaobaixuebing(yishanchu)NKlinbamuxibaobaixuebing/linbaliu(yuanshiNKxibaobaixuebing/linbaliu)【zhu】NKlinbamuxibaobaixuebing/linbaliuzaidisibanfenleizhongzuoweilinshijibingleixing,youyuquefamingquedekekaodezhenduanbiaozhunyijixiangguandexingtaixuehemianyibiaoxingtezheng,diwubanfenleizhongweidanduliechu。chengshuTxibaoheNKxibaozhongliu(9gejiazu/zhonglei,34geshiti/leixing)Mature T-cell and NK-cell neoplasms(1)chengshuTxibaoheNKxibaobaixuebing(6ge);(2)yuanfaxingpifuTxibaolinbaliu(9ge);(3)changdaoTxibaoheNKxibaolinbazengzhihelinbaliu(5ge);(4)ganpiTxibaolinbaliu(1ge);(5)jianbianxingdaxibaolinbaliu(3ge);(6)linbajieTlvpaofuzhuxibaolinbaliu(3ge);(7)qitawaizhouTxibaolinbaliu(1ge);(8)EBVyangxingNK/Txibaolinbaliu(2ge);(9)ertongEBVyangxingTxibaoheNKxibaolinbazengzhihelinbaliu(4ge)【zhu】chengshuTxibaoheNKxibaozhongliugenjuxibaoqiyuan/fenhuazhuangtai、linchuangtezheng、jibingbuwei/weizhi、xibaoxingtaixuedengqufenwei9gejiazu/zhonglei,gong34gejibingshiti/leixing。daduoshuTxibao、NKxibaozhongliukeguirugezixiangyingdeTxibao、NKxibaopuxi,danyoudejibingleixingbaokuoNKxibao、Txibao、hunhehuobuquedingdezhongliubiaoxing,TxibaoheNkxibaoqiyuandequfennanyuquedinghuobuqingchu,yincidiwubanfenleizhongmeiyoujiandandifenweiTxibaozhongliuheNKxibaolianglei,biruchengshuTxibaoheNKxibaobaixuebing、EBV-yangxingjiexingTxibaoheNKxibaolinbaliu、jiewaiNK/Txibaolinbaliudeng。diwubanfenleidisiban(xiuding)fenleichengshuTxibaoheNKxibaobaixuebingMature T-cell and NK-cell leukaemiasT-youlinbaxibaobaixuebing(T-PLL)?T-prolymphocytic leukaemiaxiangtongTdakelilinbaxibaobaixuebing(T-LGLL)?T-large granular lymphocytic leukaemiaTxibao(dakeli)linbaxibaobaixuebingNKdakelilinbaxibaobaixuebing(NK-LGLL)?NK-large granular lymphocytic leukaemiaNKxibaomanxinglinbazengshengxingjibingchengren T xibaobaixuebing/linbaliu(ATLL)?Adult T-cell leukaemia/lymphomaxiangtongSezaryzonghezheng(saizhalizonghezheng,SS)?Sézary syndromexiangtongqinxixing NK xibaobaixuebing(ANKL)?Aggressive NK-cell leukaemiaxiangtongyuanfaxingpifuTxibaolinbaliuPrimary cutaneous T-cell lymphomasyuanfaxingpifu CD4 yangxingxiao /zhongT xibaolinbazengzhixingjibing?Primary cutaneous CD4-positive small or medium T-cell lymphoproliferative disorderxiangtongyuanfaxingpifuzhiduan CD8 yangxinglinbazengzhixingjibing?Primary cutaneous acral CD8-positive lymphoproliferative disorderyuanfaxingpifuzhiduan CD8 yangxing T xibaolinbaliuzuoyangrouyazhong?Mycosis fungoides(MF)xiangtongyuanfaxingpifuCD30yangxingTxibaolinbazengzhixingjibing:linbaliuyangqiuzhenbing?Primary cutaneous CD30-positive T-cell LPD:Lymphomatoid papulosisxiangtongyuanfaxingpifuCD30yangxingTxibaolinbazengzhixingjibing:yuanfaxingpifujianbianxingdaxibaolinbaliu?Primary cutaneous CD30-positive T-cell LPD:Primary cutaneous ALCLxiangtongpixiazhimoyanyangTxibaolinbaliu?Subcutaneous panniculitis-like T-cell lymphomaxiangtongyuanfaxingpifu γ/δ T xibaolinbaliu?Primary cutaneous gamma/delta T-cell lymphomaxiangtongyuanfaxingpifuCD8yangxingqinxixingshibiaopixibaoduxingTxibaolinbaliu?Primary cutaneous CD8-positive aggressive epidermotropic cytotoxic T-cell lymphomaxiangtongyuanfaxingpifuwaizhouTxibaolinbaliu,feitezhixing(NOS)?Primary cutaneous peripheral T-cell LPD,NOSwu【zhu】yuanfaxingpifuTxibaolinbaliu(CTCL)shixinbanfenleizhongchengshuT/NKxibaozhongliuleibiexiadeyigezhuanmendejiazu/zhonglei,baokuo9gejibingshiti/leixing。changdaoTxibaoheNKxibaolinbazengzhihelinbaliuIntestinal T-cell and NK-cell Lymphoid proliferations and lymphomasweichangdaoduoxingTxibaolinbaliu?Indolent T-cell lymphoma of the gastrointestinal tractweichangdaoduoxingTxibaolinbazengzhixingjibingweichangdaoduoxing NK xibaolinbazengzhixingjibing?Indolent NK-cell lymphoproliferative disorder of the gastrointestinal tractwuchangbingxiangguanTxibaolinbaliu?Enteropathy-associated T-cell lymphomaxiangtongdanxingxingshishangpixingchangdao T xibaolinbaliu?Monomorhpic epitheliotropic intestinal T-cell lymphomaxiangtongchang daoT xibaolinbaliu,feitezhixing(NOS)?Intestinal T-cell lymphoma ,NOSxiangtong【zhu】weichangdao(GI)duoxingTxibaolinbazengzhixingjibingxinmingmingweiweichangdaoduoxingTxibaolinbaliu,mingmingcong“linbazengzhixingjibing”dao“linbaliu”dezhuanbian,shijiyuqigaofashenglvhejibingdebosanxing,danlinchuangguochengrengranmanchang,suoyirengbaoliu“duoxing”zheyixiandingci。weichangdaoduoxingNKxibaolinbazengzhixingjibing(iNKLPD,indolent NK-cell lymphoproliferative disorder)shixinzengleixing,jiwangrenweishiyizhongfanyingxingguochengerchengweilinbaliuyangweibinghuoNKxibaochangbing,danzuijindefaxianzhichitadezhongliuxingtezheng,yincixinyinruzuoweiyigedulidejibingshiti/leixing。ganpiTxibaolinbaliuHepatosplenic T-cell lymphomaganpiTxibaolinbaliu(HSTCL)?Hepatosplenic T-cell lymphomaxiangtongjianbianxingdaxibaolinbaliuAnaplastic large cell lymphomaALK-yangxingjianbianxingdaxibaolinbaliu?ALK-positive anaplastic large cell lymphoma(ALK+ALCL)jianbianxingdaxibaolinbaliu, ALK-yangxingALK-yinxingjianbianxingdaxibaolinbaliu?ALK-negative anaplastic large cell lymphoma(ALK-ALCL)jianbianxingdaxibaolinbaliu, ALK-yinxingrufangzhiruwuxiangguanjianbianxingdaxibaolinbaliu?Breast implant-associated anaplastic large cell lymphoma(BIA-ALCL)xiangtong【zhu】jianzhibianxingdaxibaolinbaliu(ALCL)jiazubaokuo3gejibingshiti/leixing:ALK+ALCL、ALK-ALCL、BIA-ALCL。junweichengshuTxibaolinbaliu,CD30qiangbiaoda,tongchangbubiaodaTxibiaozhiwu。yuanfaxingpifuALCLmeiyouguizaigaijiazuxia,ershiguileidaolingyijiazu“yuanfaxingpifuTxibaolinbazengzhihelinbaliu”xia,qiyuquanshenxingALK-ALCLxiangbiyuhougengjia。rufangzhiruwuxiangguandeALCLshiyizhongbutongyuqitaALK-ALCLdejibingleixing,shiyizhongfeiqinruxingzhongliu,yucucaobiaomianrufangzhiruwuxiangguan,linchuangyuhouxiangduijiaohao,danruguoqinfanlinjinjiegouzeyuhoubiancha。linbajieTlvpaofuzhu(TFH)xibaolinbaliuNodal T-follicular helper(TFH) cell lymphomalinbajieTFHxibaolinbaliu,xueguanmianyimuxibaoxing?Nodal TFH cell lymphoma ,angioimmunoblastic-type(nTFHL-AI)xueguanmianyimuxibaoxingTxibaolinbaliu(AITL)linbajieTFHxibaolinbaliu,lvpaoxing?Nodal TFH cell lymphoma ,follicular-type(nTFHL-F)lvpaoxingTxibaolinbaliulinbajieTFHxibaolinbaliu,feitezhixing?Nodal TFH cell lymphoma ,NOS(nTFHL-NOS)juyouTFHbiaoxingdejiexingwaizhouTxibaolinbaliu【zhu】linbajielvpaofuzhuxingTxibaolinbaliu(nTFHL)jiazubaokuo3gejibingshiti/leixing,junxilinbajieTxibaolinbaliu,juyouTFH(lvpaofuzhuxingTxibao)debiaoxinghejiyinbiaodatezheng。nTFHL-AI,angioimmunoblastic-type duiyingyuyiqiande“xueguanmianyimuxibaoxingTxibaolinbaliu”nTFHL-F,ollicular-type duiyuyingyuyiqiande“lvpaoTxibaolinbaliu”nTFHL-NOS duiyingyuyiqiande“juyouTFHbiaoxingdewaizhouTxibaolinbaliu”qitawaizhouTxibaolinbaliuwaizhouTxibaolinbaliu,feitezhixing(NOS)?Peripheral T-cell lymphoma,not otherwise specified(NOS)xiangtong【zhu】PTCL-NOSshiyizuyizhixinghenqiangdejibing,shipaichuxingzhenduan,tebieyaojianbienTFHL。EBVyangxingNK/TxibaolinbaliuEBV-positive NK/T-cell lymphomasEBVyangxingjiexingTxibaoheNKxibaolinbaliu?EBV-positive nodal T- and NK-cell lymphomawujiewaiNK/Txibaolinbaliu(ENKTL)?Extranodal NK/T-cell lymphomajiewaiNK/Txibaolinbaliu,bixing【zhu】jiewaiNK/Txibaolinbaliu(ENKTL)kefashengzaibutongdejiewaibuwei,yincishanchujiubanzhongdexiandingci“bixing”。EBVyangxingjiexingTxibaoheNKxibaolinbaliujiwangbeiguiruPTCL-NOSxiadeyigeyaxing,zaixinbanfenleizhongzuoweiyigedulidejibingshiti/leixing,zhuyaofashengzaidongyarenzhong,yuhoucha。ertongEBVyangxingTxibaoheNKxibaolinbazengzhihelinbaliuEBV-positive T- and NK-cell lymphoid proliferations and lymphomas of childhoodyanzhongwenchongdingyaoguomin?Severe mosquito bite allergyxiangtongzhongdouyangshuizuobinglinbazengzhixingjibing?Hydroa vacciniforme LPD(HVLPD)zhongdouyangshuizuobingyang(Hydroa vacciniforme-like)linbazengzhixingjibingxitongxingmanxinghuodongxingEBVjibing(xitongxingCAEBVD)?Systemic chronic active EBV diseaseTxibaoheNKxibaoleixingdemanxinghuodongxingEBVganran,xitongxingertongxitongxingEBVyangxingTxibaolinbaliu?Systemic EBV-positive T-cell lymphoma of childhoodxiangtong【zhu】(1)manxinghuodongxingEBVbing(CAEBVD):baokuojuzaozhengzhuanghe/huoduoxingxingshideyanzhongwenchongdingyaoguomin?heHVLPDjingdianxing?,yijiquanshenxingjibingHVLPDquanshenxing?hexitongxingCAEBVD?。(2)ertongxitongxingEBVyangxingTxibaolinbaliu?Hydroa vacciniforme(zhongdouyangshuizuobing,douchuangyangshuizuobing)linbazuzhidejianzhiyuanxingzhongliuStroma-derived neoplasms of lymphoid tissues(7geshiti/leixing)diwubanfenleidisiban(xiuding)fenleijianzhishutuxibaozhongliuMesenchymal dendritic cell neoplasmslvpaoshutuxibaorouliu?Follicualr dendritic cell sarcomaxiangtongEBV-yangxingyanxinglvpaoshutuxibaorouliu?EBV-positive inflammatory follicular dendritic cell sarcomayanxingjialiuyanglvpao/chengxianweixibaoshutuxibaorouliuxianweimuxibaowangzhuangxibaoliu?Fibroblastic reticular cell tumorxiangtongjixianweimuxibaoliuMyofibroblastic tumourjieneizhalanzhuangjixianweimuxibaoliu?Intranodal palisaded myofibroblastomawupiteyixingxueguanjianzhizhongliuSpleen-specific vascular-stromal tumourspixueguanjianzhiliuSplenic vascular-stromal tumourspizuoanxibaoxueguanliu?Littoral cell angiomawupicuogouliu?Splenic hamartomawupiyinghuaxingxueguanliuyangjiejiexingzhuanhua?Sclerosing angiomatoid nodular transformation of spleenwu【zhu】1、linbazuzhijianzhiyuanxingzhongliudemouxieleixingshilinbajiehuopizangsuoteyoude,guirubenfenleitixizhong。feilinbajiehepizangteyixingderuanzuzhizhongliu(biruxueguanliu、xueguanrouliu、linbaguanjiliu、kaboxirouliudeng)guidao2020niandiwubanWHOguheruanzuzhizhongliufenleizhong。2、linbazuzhijianzhi(jizhi)laiyuanzhongliushidiwubanxinyinrudefenlei,gaileibiexiabaokuosandalei:(1)jianzhishutuxibaozhongliu:cong“zuzhixibaoheshutuxibaozhongliu”leibiezhongyiguolaidelvpaoshutuxibaozhongliu(?he?)hechengxianweiwangzhuangxibaozhongliu?guiruzheyixinleibiemingxia(yinweilvpaoshutuxibaobingfeiyuanzizaoxueganxibao,ershijianzhilaiyuan)。lingwai,EBVyangxingyanxinglvpaoshutuxibaorouliu?youyujuyoudutedelinchuangbinglitezheng,conglvpaoshutuxibaorouliu?zhongdanliechulaizuoweidulidejibingleixing。(2)jixianweimuxibaoliu,xilinbajieteyixingjianzhizhongliu(linbajieneizhalanzhuangjixianweimuxibaoliu?)。(3)piteyixingjianzhizhongliu,baokuo:pizuoanxibaoxueguanliu?、picuogouliu?、piyinghuaxingxueguanliuyangjiejiexingzhuanhua?)。shutuxibaohezuzhixibaozhongliuDendritic cell and histiocytic neoplasms(11geshiti/leixing)diwubandisiban(xiuding)fenleijiangxibaoyangshutuxibaozhongliuPlasmacytoid dendritic cell neoplasmsyusuixizhongliuxiangguandechengshujiangxibaoyangshutuxibaozengzhiMature plasmacytoid dendritic cell proliferation associated with myeloid neoplasmwumuxibaoxingjiangxibaoyangshutuxibaozhongliuBlastic plasmacytoid dendritic cell neoplasmwulanggehansixibaoheqitashutuxibaozhongliuLangerhans cell and other dendritic cell neoplasmslanggehansixibaozhongliuLangerhans cells neoplasmslanggehansixibaozuzhixibaozengshengzhengLangerhans cell histiocytosisxiangtonglanggehansixibaorouliuLangerhans cell sarcomaxiangtongqitashutuxibaozhongliuOther dendritic cell neoplasmsweidingleishutuxibaoliuIndeterminate dendritic cell tumourxiangtong(weiquedingshutuxibaozhongliu)zhituzhuangshutuxibaorouliuInterdigitating dendritic cell sarcomaxiangtong(jiaozhishutuxibaorouliu)zuzhixibaozhongliuHistiocytic neoplasmsyounianhuangserouyazhongJuvenile xanthogranulomaxiangtong(bosanxingyounianhuangserouyazhong)Erdheim-Chesterbing(ECD)Erdheim-Chester diseasexiangtongRosai-Dorfmanbing(RDD)Rosai-Dorfman diseasewuALKyangxingzuzhixibaozengshengzhengALK-positive histiocytosiswuzuzhixibaorouliuHistiocytic sarcomaxiangtong【zhu】zuzhixibao/shutuxibaozhongliuzaixinbanfenleitixizhongdingweiyusuixizhongliuzhihou,tongchangrenweitamenqiyuanyuchangjiandesuixizuxibao(suixizuxibaochanshengdanhexibao/zuzhixibao/shutuxibaopuxi)。disibanzuzhixibao/shutuxibaozhongliuxiade“lvpaoshutuxibaorouliu”、“chengxianwei(xianweimuxibao)wangzhuangxibaozhongliu”,kaolvdaoshiyoulinbajizhixibaochanshengdezhongliu,diwubanfenleijiangqicongzuzhixibao/shutuxibaozhongliuzhongfenchulaiguirudaolinxizhongliu“linbazuzhijianzhiyuanxingzhongliu”xia。cankaowenxian:(1)The 5th edition of the World Health Organization Classifification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms. Leukemia(2022) 36:1703-1719.https://doi.org/10.1038/s41375-022-01613-1.(2)The 5th edition of the World Health Organization Classifification of Haematolymphoid Tumours: Lymphoid Neoplasms. Leukemia(2022) 36:1720-1748.https://doi.org/10.1038/s41375-022-01620-2.
自(窜颈)来(尝补颈)水(厂丑耻颈)的(顿别)蜕(罢耻颈)变(叠颈补苍)记(闯颈):一(驰颈)位(奥别颈)老(尝补辞)上(厂丑补苍驳)海(贬补颈)人(搁别苍)的(顿别)养(驰补苍驳)鱼(驰耻)新(齿颈苍)体(罢颈)验(驰补苍)|大(顿补)家(闯颈补)古(骋耻)美(惭别颈)
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后来这叁个人也决定去到《五哈》里边在这里边叁个人脸上的笑给人一种是真正很开心的感觉