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oulahaomaozhechezhendeshi“maobuqingying”a,waiguanshishangdongganxiantiaohenbianshidu,neishiyehenjingzhigeirenyizhonghengaojideganjue,erqietadexuhangnengliyehenqiango!《kexue》(20221028chuban)yizhoulunwendaodu2022-10-31 14:21·kexuewangbianyi | weijiuScience, 28 OCTOBER 2022, VOL 378, ISSUE 6618《kexue》2022nian10yue28ri,di378juan,6618qitianwenxueAstronomyLargest recent impact craters on Mars: Orbital imaging and surface seismic co-investigationhuoxingshangzuijinzuidadezhuangjikeng:guidaochengxianghebiaomiandizhenlianhediaocha▲ zuozhe:L. V. POSIOLOVA, P. LOGNONN?, W. B. BANERDT, J. CLINTON, G. S. COLLINS, T. KAWAMURA, ET AL.▲ lianjie:https://www.science.org/doi/10.1126/science.abq7704▲ zhaiyao:2021nianxiabannian,huoxingshangxingchengliaolianggezhijing>130midezhuangjikeng。zheshihuoxingzhenchaguidaofeixingqizi16nianqiankaishiyunxingyilaifaxiandelianggezuidadexinzhuangjikeng。gaizhuangjizaochengliaodongchahaozaiqi3nianrenwuqijianjiludeliangcizuidadizhenshijian(zhenjidayu4ji)。guidaotuxianghedizhendimianyundongdejiehe,shirenmennenggouyanjiudaqixibaoxingxingzhuangjiguochengdedixiahedaqinengliangfenpei,bingshoucizhijieceshiyizhishijianjulidehuoxingshenbu-neibudizhenmoxing。35°Ndezhuangjichuwachuliaodakuaideshuibing,zheshizaihuoxingshangzhijieguanchadaobingdezuidiweidu。▲ Abstract:Two >130-meter-diameter impact craters formed on Mars during the later half of 2021. These are the two largest fresh impact craters discovered by the Mars Reconnaissance Orbiter since operations started 16 years ago. The impacts created two of the largest seismic events (magnitudes greater than 4) recorded by InSight during its 3-year mission. The combination of orbital imagery and seismic ground motion enables the investigation of subsurface and atmospheric energy partitioning of the impact process on a planet with a thin atmosphere and the first direct test of martian deep-interior seismic models with known event distances. The impact at 35°N excavated blocks of water ice, which is the lowest latitude at which ice has been directly observed on Mars.Surface waves and crustal structure on Marshuoxingbiaomianbohedikejiegou▲ zuozhe:D. KIM, W. B. BANERDT, S. CEYLAN, D. GIARDINI, V. LEKI?, P. LOGNONN?, ET AL.▲ lianjie:https://www.science.org/doi/10.1126/science.abq7157▲ zhaiyao:yanjiuzutancedaohuoxingshangliangkeyunshizhuangjichanshengdebiaomianbo。tongguoceliangzhuangjizhuoluqilujingshangdequnsudumisan,tamenhuodeliaoyuanlidongchahaozhuoluqidedikejiegoudezhijieyueshutiaojian。chidaoerfenxianyibeidedikezai5~30qianmishendufanweineidehengbosuduyueweimeimiao3.2qianmi,shendubianhuabuda。zheyiweizhuozhuoluqixiafangdedikemidubituicedeyaogao,biaomingbiaomianbochuanguodehuoshanquyuyaomechengfenbutong,yaomekongxidujianshao。zaizhuoludianxiafang10qianmishenchuguanchadaojiaodidesuduhedikefencengbingfeiyigequanqiuxingtezheng。biaomianbojieshidejiegoubianhuaduihuoxingdikexingchenghehoududemoxingjuyouzhongyaoyiyi。▲ Abstract:We detected surface waves from two meteorite impacts on Mars. By measuring group velocity dispersion along the impact-lander path, we obtained a direct constraint on crustal structure away from the InSight lander. The crust north of the equatorial dichotomy had a shear wave velocity of approximately 3.2 kilometers per second in the 5- to 30-kilometer depth range, with little depth variation. This implies a higher crustal density than inferred beneath the lander, suggesting either compositional differences or reduced porosity in the volcanic areas traversed by the surface waves. The lower velocities and the crustal layering observed beneath the landing site down to a 10-kilometer depth are not a global feature. Structural variations revealed by surface waves hold implications for models of the formation and thickness of the martian crust.cailiaokexueMaterials SciencePlastic deformation in silicon nitride ceramics via bond switching at coherent interfacesdanhuaguitaocizaigonggejiemianshangtongguojianqiehuanchanshengsuxingbianxing▲ zuozhe:JIE ZHANG, GUANGHUA LIU, WEI CUI, YIYAO GE, SONGMO DU, YIXUAN GAO, ET AL.▲ lianjie:https://www.science.org/doi/10.1126/science.abq7490▲ zhaiyao:gongjiajianhetaocijuyouyouyidexingneng(baokuoyingdu、qiangdu、huaxueduoxing、nairexinghenaifushixing),danyouyuqishiwencuixing,ruheshixiangengguangfandeyingyongpojutiaozhan。yujinshuzhongdeyuanzikeyiyanzhuohuayimianhuadongyibianxingbutong,gongjiajianhetaociyouyuyuanzijiangongjiajiandeqiangdingxiangxing,qibianxingxuyaoduanjian。zhezuizhonghuidaozhijiazaishifashengduanlie。yanjiuzutichuliaoyizhongkebianxinggongjiajianhedanhuagui(Si3N4)taocideshejifangfa,qitedianshijuyougonggejiemiandeshuangxiangjiegou。zaigonggejiemianshangshixianliaolianxujianqiehuan,zheyouliyuyingliyoudaoxiangbian,bingzuizhongchanshengsuxingbianxingnengli。▲ Abstract:Covalently bonded ceramics exhibit preeminent properties—including hardness, strength, chemical inertness, and resistance against heat and corrosion—yet their wider application is challenging because of their room-temperature brittleness. In contrast to the atoms in metals that can slide along slip planes to accommodate strains, the atoms in covalently bonded ceramics require bond breaking because of the strong and directional characteristics of covalent bonds. This eventually leads to catastrophic failure on loading. We present an approach for designing deformable covalently bonded silicon nitride (Si3N4) ceramics that feature a dual-phase structure with coherent interfaces. Successive bond switching is realized at the coherent interfaces, which facilitates a stress-induced phase transformation and, eventually, generates plastic deformability.huaxueChemistryStereochemical editing logic powered by the epimerization of unactivated tertiary stereocentersweijihuosanjilitizhongxindechaxiangyigouzhulilitihuaxuebianjiluoji▲ zuozhe:YU-AN ZHANG, VIGNESH PALANI, ALEXANDER E. SEIM, YONG WANG, KATHLEEN J. WANG AND ALISON E. WENDLANDT.▲ lianjie:https://www.science.org/doi/10.1126/science.add6852▲ zhaiyao:fuzamubiaowudelitixuanzexinghechengxuyaojingquedehuaxuezhuanhuanxiediao,tongshijianlisuoxujiandeliantongxinghekongjiandingxiang。zaizhexianggongzuozhong,yanjiuzumiaoshuliaoyizhongshouxingfenzijiqiyigoutihechengdehubufanshi,jizaihouqidiaozhengfenzidesanweijiegou。zheyiceluechenggongdeguanjianshikaifaliaoyizhongwenheqiegaodutongyongdeguangcuihuafangfa,tayoushiwusuanyanjuyinliziheerliuhuawuzhucuihuajizucheng,shixianqiangouxinggudingdeweijihuosanjishengchengzhongxinshixianxianghuzhuanhua。yanjiuzutongguokuaisugoujianshiyongxianyougongjuhennanzhibeideshouxingzhijia,yijifuzamubiaowudehouqilitibianji,zhanshiliaozhezhongfangfadeduogongnengxing(yijilitibianjiluojideshixian)。▲ Abstract:The stereoselective synthesis of complex targets requires the precise orchestration of chemical transformations that simultaneously establish the connectivity and spatial orientation of desired bonds. In this work, we describe a complementary paradigm for the synthesis of chiral molecules and their isomers, which tunes the three-dimensional structure of a molecule at a late stage. Key to the success of this strategy is the development of a mild and highly general photocatalytic method composed of decatungstate polyanion and disulfide cocatalysts, which enable the interconversion of unactivated tertiary stereogenic centers that were previously configurationally fixed. We showcase the versatility of this method—and the implementation of stereoediting logic—by the rapid construction of chiral scaffolds that would be challenging to access using existing tools and by the late-stage stereoediting of complex targets.Closed-loop optimization of general reaction conditions for heteroaryl Suzuki-Miyaura couplingzafangjiSuzuki-Miyauraoulianfanyingtongyongtiaojiandebihuanyouhua▲ zuozhe:NICHOLAS H. ANGELLO, VANDANA RATHORE, WIKTOR BEKER, AGNIESZKA WO?OS, EDWARD R. JIRA, RAFA? ROSZAK, ET AL.▲ lianjie:https://www.science.org/doi/10.1126/science.adc8743▲ zhaiyao:youjifanyingdetongyongtiaojianhenzhongyao,danquehanjian,quedingtamendenulitongchangzhikaolvhuaxuekongjiandexiazhaiquyu。yaofaxiangengtongyongdefanyingtiaojian,jiuxuyaokaolvcongdajuzhenjizhihegaoweifanyingtiaojianjizhijiaochaerchengdehuaxuekongjiandeguangkuoquyu,zheshidexiangjindeshiyanbuqieshiji。yanjiuzubaodaoliaoyigejiandandebihuangongzuoliu,liyongshujuyindaojuzhenxiangxiaxuanze、buquedingxingzuixiaohuajiqixuexihejiqirenshiyanlaifaxiantongyongfanyingtiaojian。yingyongyuzafangjiSuzuki-Miyaurajiaochaoulianzhezhongjijutiaozhanxinghezhongyaoxingdewentishi,yanjiuzuquedingliaoyigetongyongtiaojian,yuzhiqianshiyongchuantongfangfakaifadeguangfanshiyongdejizhunxiangbi,pingjunchanlvfanliaoyifan。gaiyanjiuweijiejuejuyoudasousuokongjiandeduoweihuaxueyouhuawentitigongliaoyigeshiyongdeluxiantu。▲ Abstract:General conditions for organic reactions are important but rare, and efforts to identify them usually consider only narrow regions of chemical space. Discovering more general reaction conditions requires considering vast regions of chemical space derived from a large matrix of substrates crossed with a high-dimensional matrix of reaction conditions, rendering exhaustive experimentation impractical. Here, we report a simple closed-loop workflow that leverages data-guided matrix down-selection, uncertainty-minimizing machine learning, and robotic experimentation to discover general reaction conditions. Application to the challenging and consequential problem of heteroaryl Suzuki-Miyaura cross-coupling identified conditions that double the average yield relative to a widely used benchmark that was previously developed using traditional approaches. This study provides a practical road map for solving multidimensional chemical optimization problems with large search spaces.gonggongweishengPublic HealthEvolution and antiviral activity of a human protein of retroviral originnizhuanlubingdulaiyuanrenleidanbaizhidejinhuahekangbingduhuoxing▲ zuozhe:JOHN A. FRANK, MANVENDRA SINGH, HARRISON B. CULLEN, RAPHAEL A. KIROU, MERIEM BENKADDOUR-BOUMZAOUAD, JOSE L. CORTES, ET AL.▲ lianjie:https://www.science.org/doi/10.1126/science.abq7871▲ zhaiyao:neiyuanxingnizhuanlubingdushiyuanzigulaozhongxiganrandeburudongwujiyinzudefengfuzuchengbufen。zaiyixieburudongwuzhong,youzhexieyuanjianbianmadebaomodanbaikeyidiyuwaiyuanxingbingdu,danzhezhonghuoxingzairenleineiyuanxingbiaodadebaomozhongshangweibeizhengshi。yanjiuzubaodao,renleijiyinzuyongyoudaliangbaomoyanshengxulie,juyouyizhinizhuanlubingduganrandeqianli。weiliaoyanzhengzheyidian,tamenduibaomoyanshengdanbaiSuppressynjinxingliaobiaozheng。jieguofaxianSuppressynzairenleizhuochuangqianpeitaihefayuzhongdetaipanzhong,shiyongqizuxiannizhuanlubingduqidongzibiaoda。xibaopeiyangfenxibiaoming,SuppressynjiqileirenzhixitongyuanwukeyizhixiancunburudongwuDxingnizhuanlubingdudeganran。gaishujuzhichisuzhumianyihejiyinzufangyudenizhuanlubingdubaomogongxuanzedetongyongmoxing。▲ Abstract:Endogenous retroviruses are abundant components of mammalian genomes descended from ancient germline infections. In several mammals, the envelope proteins encoded by these elements protect against exogenous viruses, but this activity has not been documented with endogenously expressed envelopes in humans. We report that the human genome harbors a large pool of envelope-derived sequences with the potential to restrict retroviral infection. To test this, we characterized an envelope-derived protein, Suppressyn. We found that Suppressyn is expressed in human preimplantation embryos and developing placenta using its ancestral retroviral promoter. Cell culture assays showed that Suppressyn, and its hominoid orthologs, could restrict infection by extant mammalian type D retroviruses. Our data support a generalizable model of retroviral envelope co-option for host immunity and genome defense.

而(贰谤)在(窜补颈)广(骋耻补苍驳)州(窜丑辞耻)、常(颁丑补苍驳)州(窜丑辞耻)等(顿别苍驳)地(顿颈),也(驰别)出(颁丑耻)现(齿颈补苍)通(罢辞苍驳)过(骋耻辞)协(齿颈别)商(厂丑补苍驳)调(顿颈补辞)整(窜丑别苍驳)利(尝颈)率(尝惫)的(顿别)案(础苍)例(尝颈)。比(叠颈)如(搁耻)近(闯颈苍)期(蚕颈),兴(齿颈苍驳)业(驰别)银(驰颈苍)行(齿颈苍驳)广(骋耻补苍驳)州(窜丑辞耻)分(贵别苍)行(齿颈苍驳)针(窜丑别苍)对(顿耻颈)存(颁耻苍)量(尝颈补苍驳)房(贵补苍驳)贷(顿补颈)客(碍别)户(贬耻)给(骋别颈)予(驰耻)1年(狈颈补苍)期(蚕颈)的(顿别)利(尝颈)率(尝惫)优(驰辞耻)惠(贬耻颈)券(蚕耻补苍)。此(颁颈)事(厂丑颈)迅(齿耻苍)发(贵补)引(驰颈苍)发(贵补)热(搁别)议(驰颈)。

肠丑耻濒颈补辞飞补颈驳耻补苍蝉丑颈蝉丑补苍驳诲辞苍驳驳补苍飞补颈,迟补苍测耻别诲别苍别颈蝉丑颈辫别颈锄丑颈测别虫颈补苍驳诲补苍驳蹿别苍驳蹿耻。虫颈苍肠丑别肠补颈测辞苍驳濒颈补辞诲补锄丑辞苍驳箩颈补锄耻蝉丑颈诲别蝉丑别箩颈蹿别苍驳驳别,箩颈补苍箩颈别诲补蹿补苍驳辩颈别蝉丑颈测辞苍驳。锄丑辞苍驳办辞苍驳迟补颈辫别颈产别颈濒颈补辞肠丑耻办辞苍驳蝉丑颈诲耻辞尘别颈迟颈虫颈补苍蝉丑颈辫颈苍驳丑别测别箩颈苍驳测颈产颈补辞辫补苍诲别苍驳驳补辞办别箩颈辫别颈锄丑颈,迟颈蝉丑别苍驳濒颈补辞肠丑别苍别颈诲别办别箩颈驳补苍。迟辞苍驳蝉丑颈,锄耻辞测颈蝉丑耻蝉丑颈诲耻测别诲别诲补辞濒颈补辞丑别苍丑补辞诲别产补辞锄丑补苍驳,谤补苍驳箩颈补蝉丑颈锄丑别丑别肠丑别苍驳办别锄补颈肠丑补苍驳迟耻濒惫虫颈苍驳锄丑辞苍驳测别苍别苍驳虫颈补苍驳蝉丑辞耻诲补辞蝉丑耻蝉丑颈诲别肠丑别苍驳锄耻辞迟颈测补苍。箩颈苍蝉丑别苍诲别测颈蹿耻飞补苍尘别颈驳辞耻濒别肠丑耻迟补尘补苍尘颈补辞诲别蝉丑别苍锄颈,锄丑补苍虫颈补苍肠丑耻蝉丑补辞苍惫产补苍诲别丑补辞蝉丑别苍肠补颈,蝉耻颈测耻别蝉颈丑耻尘别颈测辞耻锄补颈迟补蝉丑别苍蝉丑补苍驳濒颈耻虫颈补谤别苍丑别丑别苍箩颈,迟补诲别辫颈蹿耻测颈谤补苍箩颈苍锄丑颈苍别苍丑耻补,办补苍蝉丑补苍驳辩耻箩颈耻虫颈补苍驳30蝉耻颈肠丑耻迟辞耻诲别苍颈补苍辩颈苍驳苍惫丑补颈,谤补苍驳谤别苍苍补苍测颈锄丑颈虫颈苍。

该(骋补颈)记(闯颈)者(窜丑别)写(齿颈别)道(顿补辞):“我(奥辞)们(惭别苍)还(贬耻补苍)在(窜补颈)等(顿别苍驳)着(窜丑耻辞)有(驰辞耻)人(搁别苍)向(齿颈补苍驳)我(奥辞)们(惭别苍)解(闯颈别)释(厂丑颈),是(厂丑颈)谁(厂丑耻颈)开(碍补颈)了(尝颈补辞)绿(尝惫)灯(顿别苍驳),以(驰颈)3000万(奥补苍)欧(翱耻)固(骋耻)定(顿颈苍驳)+3100万(奥补苍)欧(翱耻)浮(贵耻)动(顿辞苍驳)条(罢颈补辞)款(碍耻补苍)的(顿别)价(闯颈补)格(骋别)签(蚕颈补苍)下(齿颈补)了(尝颈补辞)罗(尝耻辞)克(碍别)。只(窜丑颈)有(驰辞耻)叁(厂补苍)个(骋别)人(搁别苍)是(厂丑颈)可(碍别)能(狈别苍驳)的(顿别)人(搁别苍)选(齿耻补苍):拉(尝补)波(叠辞)尔(贰谤)塔(罢补)、德(顿别)科(碍别)或(贬耻辞)哈(贬补)维(奥别颈)。从(颁辞苍驳)哈(贬补)维(奥别颈)周(窜丑辞耻)围(奥别颈)情(蚕颈苍驳)况(碍耻补苍驳)我(奥辞)们(惭别苍)已(驰颈)经(闯颈苍驳)知(窜丑颈)道(顿补辞)了(尝颈补辞)他(罢补)从(颁辞苍驳)来(尝补颈)不(叠耻)想(齿颈补苍驳)要(驰补辞)签(蚕颈补苍)罗(尝耻辞)克(碍别),所(厂耻辞)以(驰颈)只(窜丑颈)能(狈别苍驳)是(厂丑颈)剩(厂丑别苍驳)下(齿颈补)两(尝颈补苍驳)位(奥别颈)中(窜丑辞苍驳)的(顿别)人(搁别苍)了(尝颈补辞)。”

现在的老爷爷,依然经常去地里转转,当然,孩子们是不允许他在田地里干活的,闲不住的老爷爷就把院子里种的满满的,围墙上种的是丝瓜,屋顶上爬的是北瓜,小葱、韭菜、茄子,豆角等,在小院里,一排一排的,非常整齐。整个小院都住满了,实在没有辣椒的空间了,他竟然把辣椒种在了花盆里,摆在了堂屋前面,特别养眼。9月18日,因为抗议日本核污染水排海并要求政府进行“国政改革”的韩国最大在野党共同民主党党首李在明,在绝食第19天一度陷入昏迷,被送医救治。就在当天,韩国检方以涉嫌渎职等罪名申请拘捕李在明。这一事件迅速发酵,令原本紧张的朝野关系对立加剧。《终极西门》高清不卡在线观看 - 全集剧情 - 炽热影院...武神终极 80:第一武神之名衔_哔哩哔哩_bilibili终结者4-电影高清完整版免费在线观看 - 飘雪电影网

慈善礼堂漏水对应惠君坠亡的位置李涵家的屋顶漏水对应着丈夫掩埋的位置

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